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PARP inhibitors as therapy for small cell lung carcinoma: A systematic review and meta-analysis of clinical trials
Published 2024-01-01“…The analysis showed increased Progression-Free Survival (PFS) (RR 0.92 (95 %CI 0.84–1.00; p=0.05)) and Objective Response Rate (ORR) (RR 1.27 (95 %CI 1.07–1.50; p=0.007)), no significant difference in Overall Survival (OS) (RR 1.03 (95 %CI 0.92–1.15; p=0.60)), and an increased risk for serious Treatment Emergent Adverse Events (TEAEs) (RR 1.13 (95 %CI 0.95–1.35; p=0.16)) in PARPi-receiving SCLC patients. …”
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A Unique Case of Mantle Cell Lymphoma Masquerading as a Cecal Mass
Published 2021-01-01“…Treatment involves conventional chemo-immunotherapy consisting of R CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) or RB (rituximab and bendamustine), with the latter being better tolerated and associated with longer progression-free survival. Surgical resection is usually limited to patients in which complications are seen such as bleeding, perforation, or bowel obstruction. …”
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Authors' Reply: Commentary on “Protecting User Privacy and Rights in Academic Data-Sharing Partnerships: Principles From a Pilot Program at Crisis Text Line”
Published 2025-01-01“…We recognize the complexity and evolving nature of the challenges surrounding data-sharing partnerships in digital health research. As the field progresses, we remain committed to ongoing, transparent engagement and to refining best practices in collaboration with colleagues, stakeholders, and the public. …”
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Network Meta-Analysis of Once Weekly Selinexor-Bortezomib-Dexamethasone in Previously Treated Multiple Myeloma
Published 2021-08-01“…**Methods**: Ovid was systematically searched for phase 2-3 randomized clinical trials (RCTs) in MM that assessed progression-free survival (PFS), overall survival (OS) and overall response rates (ORR). …”
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VICTIM OF AN OFFENCE: LEGAL AND ECONOMIC ANALYSIS IN AN INTERJURISDICTIONAL CONTEXT
Published 2024-12-01“…It includes both legal mechanisms to protect victims within the EU and to monitor the progress of such protection at the international level. …”
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15790
Pimavanserin Treatment for Parkinson’s Disease Psychosis in Clinical Practice
Published 2021-01-01“…PDP symptoms typically progress over its course from being mild, infrequent, and often untroubling to complex, sometimes constant, and potentially highly disturbing. …”
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Development of a compact near-infrared lamp furnace for synchrotron powder diffraction and its application for in situ high-temperature observation of ferrite magnets
Published 2025-12-01“…The other involves a capillary rotation system, allowing for sufficient particle statistical measurements even as crystal grain growth progresses. To demonstrate the applicability of the developed system for in situ experiments under various heating conditions, we evaluated the heating process of standard samples and in situ crystalline phase changes of Sr ferrite permanent magnet materials. …”
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Biodegradable Polymer DES (Ultimaster) vs. Magnesium Bioresorbable Scaffold (BRS Magmaris) in Diabetic Population with NSTE-ACS: A One-Year Clinical Outcome of Two Sirolimus-Elutin...
Published 2021-01-01“…Although percutaneous coronary intervention (PCI) continues to evolve, type 2 diabetes mellitus (T2DM) is a well-established marker of poor clinical prognosis after PCI, which is mainly attributed to the rapid progression of atherosclerosis requiring recurrent revascularizations. …”
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HSPB1 Regulates Autophagy and Apoptosis in Vascular Smooth Muscle Cells in Arteriosclerosis Obliterans
Published 2022-01-01“…In vivo and in vitro studies were used to determine whether HSPB1 is associated with ASO progression. The expression of HSPB1 was measured in normal and sclerotic blood vessels. …”
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Combustion Characteristics of Mui and Taru Basin Coal in a Fluidized Bed Combustor
Published 2021-01-01“…Flue gas analysis for Taru and Mui coal gave hydrogen sulfide as 20 ppm and 6 ppm, maximum carbon monoxide of 2000 ppm at 600°C, and a decrease in oxygen as combustion progressed to a minimum of 15%, followed by an increase to 20.3%, suggesting depletion of coal. …”
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Rapid Destructive Arthropathy of the Knee in Parkinson’s Disease with Pisa Syndrome: A Case of Knee-Spine Syndrome
Published 2021-01-01“…The radiographic findings progressed to Kellgren-Lawrence grade IV within a month. …”
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Onset of age, site and respiratory symptoms are strongly associated with respiratory decline in sporadic amyotrophic lateral sclerosis: a long-term longitudinal study
Published 2024-12-01“…Objective The objective of this study is to identify factors influencing progression of respiratory decline from the onset of neurological symptoms to respiratory failure in patients with amyotrophic lateral sclerosis (ALS).Methods In 100 patients with sporadic ALS, %vital capacity (%VC) was continuously measured from the first visit to the respiratory endpoint (REP). …”
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Debates on the Role of the US Theatre Missile Defense in Regional Deterrence of Russia and China
Published 2021-04-01“…At the same time, US policymakers express in that regard serious concerns about Russia’s and China’s progress in the development of hypersonic missile systems. …”
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Screening fungi for use as biocatalysts in self-healing concrete with protocol simulating concrete environment
Published 2024-09-01“…This problem critically impedes the progress of MESHC development, which has tremendous significance because concrete cracking reduces service life while making new concrete consumes substantial energy and emits a large amount of CO2. …”
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