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15501
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15502
Drought tolerance gene pool in developing adaptive varieties of durum wheat identified in study nurseries under the Kazakhstan-Siberian program
Published 2017-11-01“…In 2000–2015, durum wheat entries in the Kazakhstan-Siberian program were studied. Progress in durum wheat breeding was tested in Russian and Kazakhstan institutes. …”
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15503
Genes underlying cold acclimation in the tea plant (<i>Camellia sinensis</i> (L.) Kuntze)
Published 2020-01-01“…It has been shown that cell responses to chilling (0…+15°C) and freezing (< 0°C) are not the same and gene expression under cold stress is genotype-specific. In recent decades, progress has been made in understanding the genetic mechanisms underlying the cold response of plants – ICE1 (inducer of CBF expression 1), CBF (C-repeat-binding factor), COR (cold-regulated genes) pathways and signaling have been discovered. …”
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15504
Pregnancy-Associated Plasma Protein A Induces Inflammatory Cytokine Expression by Activating IGF-I/PI3K/Akt Pathways
Published 2019-01-01“…Together, this study demonstrates that PAPP-A activates the macrophage signaling pathway (IGF-I/PI3K/Akt), which drives the expression and production of inflammatory cytokines known to contribute to the initiation and progression of ACS. These findings indicate that PAPP-A may play a proinflammatory role in the pathophysiology of ACS and serve as a potential therapeutic target.…”
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Integrative single-cell and multi-omics analyses reveal ferroptosis-associated gene expression and immune microenvironment heterogeneity in gastric cancer
Published 2025-01-01“…Abstract Gastric cancer (GC), a prevalent malignancy worldwide, encompasses a multitude of biological processes in its progression. Recently, ferroptosis, a novel mode of cell demise, has become a focal point in cancer research. …”
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15507
Transthyretin-Related Familial Amyloidosis Polyneuropathy with Spinal Cord Damage: A Case Report
Published 2025-01-01“…The disease is characterized primarily by peripheral and autonomic nerve damage. Disease progression is associated with frequent involvement of the heart, lungs, kidneys, eyes, and other organs. …”
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15510
KLEBSIELLA PNEUMONIAE NECROTIZING FASCIITIS OF THE LOWER EXTREMITY IN A 7-MONTH-OLD MALE: A CASE REPORT
Published 2019-12-01“…Abstract: Introduction: Klebsiella pneumoniae necrotizing fasciitis is an uncommon soft tissue infection characterized by rapidly progressing necrosis involving the skin, subcutaneous tissue, and fascia. …”
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15511
Long noncoding RNAs predict the survival of patients with colorectal cancer as revealed by constructing an endogenous RNA network using bioinformation analysis
Published 2019-03-01“…Abstract Long noncoding RNAs (lncRNAs) are aberrantly expressed in various cancers types and can function as competing endogenous RNAs (ceRNAs), which promote and maintain tumor initiation and progression. In this study, we explored the functional roles and regulatory mechanisms of lncRNAs as ceRNAs in colorectal cancer and their clinical potential as biomarkers. …”
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The role of SASP in ischemic stroke: a deep dive into cellular mechanisms
Published 2025-01-01“…Ccl3 and Lcp1 might potentially modulate IS progression by influencing SASP, proffering novel prospects for IS clinical diagnosis and treatment.…”
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15516
Impact of corticosteroids on the efficacy of first-line pembrolizumab plus chemotherapy in patients with advanced non-small-cell lung cancer
Published 2025-02-01“…Methods: The primary endpoint was progression-free survival (PFS) according to SC exposure status (⩾10 mg/day), adjusted in a multivariate Cox model for the following confounders: age, performance status, hospital admission prior to treatment, number of metastatic sites, brain metastases, bone metastases, PD-L1 status, and histological subtype. …”
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15517
Analysis of vulnerability, its drivers, and strategies applied towards reducing the pastoral and agro-pastoral livelihood vulnerability to climatic shocks
Published 2025-01-01“…Furthermore, despite the government’s numerous efforts to lesson enduring vulnerabilities and their effects, progress has not been encouraging because of lack of proactive action when faced with emergences. …”
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15518
Systemic inflammation response index association with gout in hyperuricemic adults: NHANES 2007–2018
Published 2025-01-01“…Previous studies have indicated that specific strategies may be effective in preventing the progression of hyperuricemia to gout. However, there is a lack of widely applicable methods for identifying high-risk populations for gout. …”
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Network analysis of meaning in life, perceived social support, and depressive symptoms among vocational undergraduate students
Published 2025-02-01“…The present study aimed to investigate the association between meaning in life (MIL) and perceived social support (PSS) with depressive symptoms among vocational undergraduate students, employing a network analysis approach to gain a deeper understanding of the underlying pathways and to prevent the progression of depressive symptoms into disorders.MethodsA total of 1367 Chinese vocational undergraduates (Mage = 20.1, SD = 1.6; 44.7% female) were recruited and were asked to complete a series of questionnaires, including the meaning in life questionnaire, perceived social support scale, and patient health questionnaire. …”
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15520
ANTHROPOCENTRIC DIMENSIONS OF UKRAINIAN CULTURE (IN THE CONTEXT OF THE ARCHETYPE OF THE WISE OLD MAN)
Published 2020-12-01“…In particular, we can talk about the role of man (personality) in cultural progress in a particular period of development of the society. …”
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