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15001
Efficacy and safety of immunotherapy in locally advanced or metastatic pulmonary lymphoepithelioma-like carcinoma: a multicenter retrospective study
Published 2025-01-01“…Objectives: This study aimed to evaluate the efficacy of immunotherapy, either alone or in combination with chemotherapy, in improving progression-free survival (PFS) and overall survival (OS) in patients with advanced pLELC. …”
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15002
Extracranial carotid plaque calcification and its association with risk factors for cerebrovascular events: insights from the ANTIQUE study
Published 2025-01-01“…We aimed to investigate extracranial carotid calcification and its association with risk factors for ischemic cerebrovascular diseases.Materials and methodsAmong 1,863 consecutive patients in the Atherosclerotic Plaque Characteristics Associated with a Progression Rate of the Plaque and a Risk of Stroke in Patients with the Carotid Bifurcation Plaque Study (ANTIQUE), 132 symptomatic or asymptomatic patients (177 carotid plaques) with >30% carotid stenosis examined through computed tomography (CT) and magnetic resonance imaging (MRI) were included. …”
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15007
The Mediation of Circulating Inflammatory Proteins in the Causal Pathway from Immune Cells to COPD
Published 2025-02-01“…Kunrong Yan, Yingjian Wang, Peng Xin Department of Anaesthesia, Chaoyang Second Hospital, Chaoyang, Liaoning, People’s Republic of ChinaCorrespondence: Peng Xin, Email cy08xp@163.comObjective: Observational studies have indicated that immune cells and circulating inflammatory proteins may play a dual role in the progression of COPD; however, the precise mechanisms remain uncertain. …”
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15008
Quid du port romain estuarien de Barzan (Charente-Maritime) ?
Published 2020-12-01“…The banks of the estuary were deeply eroded during the last glaciation and formed valleys that were subsequently flooded during the Holocene transgression. Later, the progressive inflow of fluvio-marine sediments became increasingly important in filling up the valleys that had become marshes. …”
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15009
Economic Evaluation of Boceprevir for the Treatment of Patients with Genotype 1 Chronic Hepatitis C Virus Infection in Hungary
Published 2013-06-01“…Efficacy was estimated from SPRINT-2 and RESPOND-2 studies. Disease progression rates and health state utilities used in the model were obtained from published studies. …”
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15010
Fatal disseminated infection in a cat from Madrid, Spain
Published 2025-01-01“…Parenteral clindamycin administration (25 mg/kg IV q12h) and supportive treatment could not prevent progression to death. Cytology from the liver and lungs revealed organisms morphologically consistent with T gondii . …”
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15011
Carbon Nanomaterials in the Treatment of Infectious Bone Defects and Wound Scars after Wushu Fractures
Published 2020-01-01“…Although modern antibiotics and surgical technology have made great progress, when using carbon nanomaterials to treat bone marrow-induced inflammation after martial arts fractures, how to simultaneously repair bone defects and control wound infections is the current focus of orthopedics research. …”
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15012
In vitro sperm generation from immature mouse testicular tissue using plasma rich in growth factors
Published 2025-01-01“…Immunofluorescence and quantitative analysis confirmed enhanced spermatogenesis progression in 5% PRGF media, with significantly increased numbers of PLZF + spermatogonia, SYCP3 + spermatocytes, ACRBP + spermatids, and Ki67 + proliferating cells per tubule compared to 10% KSR. …”
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15013
Use of Sildenafil in Pulmonary Arterial Hypertension: Findings from a U.S. Healthcare Claims Database
Published 2014-02-01“…As there is no known cure for PAH, the goal of treatment is to control symptoms and slow disease progression. Sildenafil, a phosphodiesterase-5 inhibitor, has been indicated to improve exercise capacity in PAH in both the United States and the European Union since 2005; since 2009, it also has been indicated in the United States to delay clinical worsening. …”
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Acute Invasive Fungal Rhinosinusitis-Related Orbital Infection: A Single Medical Center Experience
Published 2021-01-01“…Acute invasive fungal rhinosinusitis (AIFRS) is a hazardous infectious disease with rapid progression and high mortality and morbidities. Further orbital involvement is commonly seen. …”
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15016
The Effect of Detethering Surgery on the Bladder Function and Psychology of Children with Primary Tethered Cord Syndrome
Published 2025-01-01“…Conclusions: DS could not considerably ameliorate pre-existing bladder dysfunction and patients exhibiting non-progressive bladder dysfunction could be treated conservatively with close observation. …”
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ANALYSIS OF THE APPLICATIONS OF THE DATA-DRIVEN APPROACH IN EVALUATING THE THERMAL-PHYSICAL PROPERTIES OF COMPOSITES
Published 2024-12-01“…The results have significant implications for enhancing production processes, fostering innovation, and progressing the research of composite materials across diverse industries.…”
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Thymosin β4 Protects against Cardiac Damage and Subsequent Cardiac Fibrosis in Mice with Myocardial Infarction
Published 2022-01-01“…Inflammation is a critical factor in the development and progression of myocardial infarction and cardiac fibrosis. …”
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15020
T cell receptor signaling pathway subgroups and construction of a novel prognostic model in osteosarcoma
Published 2025-01-01“…Background: T cell receptor (TCR) signaling pathway is closely related to tumor progress and immunotherapy. This study aimed to explore the clinical significance, prognosis, immune infiltration and chemotherapy sensitivity of TCR in osteosarcoma (OS). …”
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