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14481
Numerical Simulation and Optimization of Outdoor Wind Environment in High-Rise Buildings Zone of Xuzhou City
Published 2025-01-01“…The study comprehensively examines the effects of building height, width, orientation, spacing, and layout on the outdoor wind field, progressing from individual building units to clusters. …”
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14482
Perspectives on Structural, Physiological, Cellular, and Molecular Responses to Desiccation in Resurrection Plants
Published 2018-01-01“…Similarly, recent data show a major role of ABA, LEA proteins, and small regulatory RNA in regulating DT responses. Current progress in “-omic” technologies has enabled quantitative monitoring of the plethora of biological molecules in a high throughput routine, making it possible to compare their levels between desiccation-sensitive and DT species. …”
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14483
Inhibiting METTLl3-ATG5 axis-mediated harmful autophagy in macrophages could help reduce airway epithelial inflammation and remodeling in COPD
Published 2024-01-01“…We investigated the role and underlying mechanisms of methyltransferase-like 3 (METTL3) and autophagy-related protein 5 (ATG5) in the progression of COPD. In a COPD mouse model exposed to cigarette smoke, lung tissues showed increased levels of METTL3, p-p65/ p65, autophagy markers (LC3 and ATG5), inflammatory factors (interleukin-6, IL-8, and TNF-α), and airway remodeling markers (N-cadherin, α-SMA, and Tn-C), while p62 and E-cadherin levels were decreased. …”
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14484
Determining the cultural safety of chronic disease interventions for Aboriginal and Torres Strait Islander Australians: a scoping review
Published 2025-01-01“…Searches included Scopus, Informit, OVID Medline, Emcare and CINAHL including all articles published until September 2023.ResultsSearches identified 2,225 articles. 1,854 articles underwent title and abstract screening, with 97 progressing to full text review. Twenty articles met the inclusion criteria. 75% (n = 15) of articles determined cultural safety based solely on Aboriginal and Torres Strait Islander peoples’ perspectives, with community acceptance as the most common means of determining cultural safety. …”
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14485
Fibrous Dysplasia of the Ethmoid Bone Diagnosed in a 10-Year-Old Patient
Published 2024-12-01“…Surgical intervention is recommended only for patients with severe functional impairment, progressive deformities, or malignant transformation.…”
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14486
The relationship between factors affecting the development of industrial startups using methodology Fuzzy cognitive mapping
Published 2025-02-01“…Extended Abstract Introduction Knowledge and innovation are the most fundamental factors of progress in the economic and industrial fields. Transitioning from an economy dependent on primary industries and relying on the sale of raw and low-processed materials is possible only through the path of innovative economy and the production of innovative ideas (Abdollhi et al, 2020). …”
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14487
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14488
Expression of MMP1, MMP3, and TIMP1 in intervertebral discs under simulated overload and microgravity conditions
Published 2025-01-01“…MMP1 and MMP3 levels progressively increased with longer exposure durations, showing statistically significant differences (P < 0.01). …”
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14489
High-Dose Toremifene as a Promising Candidate Therapy for Hormone Receptor-Positive Metastatic Breast Cancer with Secondary Resistance to Aromatase Inhibitors
Published 2020-01-01“…The overall response rate (ORR) and clinical benefit rate (CBR) were compared between various clinical subgroups, including patients exhibiting primary or secondary AI resistance as defined by the timing of recurrence or progression. Time to treatment failure (TTF) was estimated by the Kaplan–Meier method and compared between subgroups by the log-rank test. …”
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14490
Integrated Bioinformatic Analysis Identifies Networks and Promising Biomarkers for Hepatitis B Virus-Related Hepatocellular Carcinoma
Published 2020-01-01“…., extracellular exosome) and signaling pathways that participate in the progression of HCC induced by HBV, serving comprehensive knowledge of the mechanisms regarding HBV-related HCC.…”
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14491
The Impact of Care Upon Alzheimer Patient’s Family Caregiver in Sulaimani City
Published 2019-06-01“…Family Care giving for relatives with Alzheimer, often includes assisting them with one or more activities of daily living, as Alzheimer is one of the progressive impairment diseases in patient’s physical and cognitive ability. …”
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14492
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14493
Transformation of the Human Image in the Paradigm of Knowledge Evolution
Published 2021-06-01“…A condition for the formation of a new anthropological type of man in the perspective of scientific and technological progress is the affirmation of ethical wisdom. Conclusions. …”
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14494
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14495
Influence of mode of delivery on infant gut microbiota composition: a pilot study
Published 2024-12-01“…Further comprehensive studies that consider geographical locations are necessary to elucidate the progression of microbiota in infants born via different delivery modes.…”
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14496
KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis
Published 2025-01-01“…BackgroundAcute lung injury (ALI) is a severe condition characterized by inflammation, tissue damage, and persistent activation of the cyclic GMP-AMP (cGAS)-stimulator of interferon genes (STING) pathway, which exacerbates the production of pro-inflammatory mediators and promotes the progression of ALI. Specific inhibition of this pathway has been shown to alleviate ALI symptoms. …”
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14497
Climate variability can outweigh the influence of climate mean changes for extreme precipitation under global warming
Published 2025-02-01“…<p>As global warming progresses, weather conditions like daily temperature and precipitation are changing due to changes in their means and distributions of day-to-day variability. …”
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14498
Assessment of greenness, blueness, and whiteness profiles of a validated HPLC-DAD method for quantitation of Donepezil HCl and Curcumin in their laboratory prepared co-formulated n...
Published 2025-01-01“…This integration of environmental consciousness into analytical practices represents a significant step forward in achieving sustainable scientific progress. In the present study, a sensitive eco-friendly HPLC-DAD method was carried out and validated to allow concurrent determination of Donepezil HCl (DPZ) and Curcumin (CUR) in their pure form and laboratory made nano-liposome formulation. …”
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14499
Management of female para-urethral cyst with dyspareunia: a case report
Published 2025-01-01“…Case presentation We present the case of a 36-year-old, sexually active, Indian (Asian) woman with a 6-month history of progressively worsening lower urinary tract symptoms, consisting of dysuria, post-micturition dribble, increased urination frequency, and significant dyspareunia. …”
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14500
Feasibility and Effectiveness of Telephone-Based Telephysiotherapy for Treatment of Pain in Low-Resource Setting: A Retrospective Pre-Post Design
Published 2020-01-01“…The treating physiotherapist made telephone calls to every patient each week to give necessary information, correction, modification, and progression of the exercise whatever required. At the end of the second and fourth weeks, pain was assessed using the Numeric Pain Rating Scale (NPRS) through telephone calls. …”
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