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14221
Effect of Double Masking with Silk or Cotton Over-masks on the Source Control Capabilities of a Surgical Mask
Published 2022-04-01“…Abstract In spite of the remarkable progress made in the development of safe and effective vaccines against COVID-19, deployment of respiratory protective devices remains vital for mitigating the transmission of SARS-CoV-2 during the ongoing pandemic. …”
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14222
Sulfatase modifying factor 2 as a predictive biomarker for urothelial carcinoma
Published 2025-02-01“…Abstract Sulfatases mediate the sulfation level of cell-surface heparan sulfates to regulate signal transduction, thereby promoting cancer progression. Sulfatase activation requires a sulfatase modifying factor (SUMF) for the modification of its catalytic domain. …”
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14223
Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases
Published 2025-01-01“…The future of nanocomposites in dermatology looks promising, with innovations in personalized medicine, smart drug delivery, and multifunctional materials driving progress. Continued research and development will be essential to unlock the full potential of nanocomposites in enhancing clinical dermatology. …”
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14224
Evaluation of the association between bevacizumab concentration and clinical outcomes in patients with breast cancer brain metastasis
Published 2025-01-01“…Although bevacizumab concentrations did not associate with therapeutic response and progression-free survival, patients with higher bevacizumab concentrations exhibited longer overall survival (adjusted HR 0.78; p = 0.039). …”
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14225
miR-134-3p Regulates Cell Proliferation and Apoptosis by Targeting INHBA via Inhibiting the TGF-β/PI3K/AKT Pathway in Sheep Granulosa Cells
Published 2024-12-01“…Moreover, cell cycle progression was enhanced by miR-134-3p overexpression. …”
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14226
Platycodin D inhibits tumor proliferation by modulating macrophage polarization through promoting JAK2 ubiquitination
Published 2025-02-01“…A growing body of evidence indicates that tumor-associated macrophages (TAMs) are crucial contributors to cancer progression, positioning them as an attractive target for therapeutic intervention. …”
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14227
The pro-inflammatory cytokine Tumor Necrosis Factor alpha (TNF-α) in Diabetic Nephropathy
Published 2024-07-01“…Regretfully, we still don't fully understand the mechanisms underlying the onset and progression of renal injury in diabetes. There is now proof that inflammation and activated innate immunity play important roles in the etiology of problems with diabetes. …”
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14228
Nephrotic Syndrome and Idiopathic Membranous Nephropathy Associated with Autosomal-Dominant Polycystic Kidney Disease
Published 2011-01-01“…Findings in this patient also suggest that MFM might reduce cystic cell proliferation and fibrosis, preventing progressive renal scarring with preservation of renal function.…”
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14229
CD4+CD25highCD127low/−FoxP3+ Regulatory T Cell Subpopulations in the Bone Marrow and Peripheral Blood of Children with ALL: Brief Report
Published 2018-01-01“…This small subset of T cells has been, in fact, considered to be involved in the pathogenesis of autoimmune diseases and progression of acute and chronic leukemias. However, whether Treg dysregulation in CLL and ALL plays a key role or it rather represents a simple epiphenomenon is still a matter of debate. …”
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14230
Spermatozoa motility and viability of turkey (Meleagris gallopavo) semen in egg yolk nanoparticles-phosphate buffered saline extender at 3-5°C storage
Published 2024-11-01“…Extended semen was stored in a refrigerator (3-5°C), and progressive spermatozoa motility and viability were evaluated every two hours until spermatozoa motility decreased to 40%. …”
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14231
CASE REPORT ON TWO CONSECUTIVE PATIENTS WITH NEUROINVASIVE WEST NILE VIRUS INFECTION IN AN INTENSIVE CARE UNIT
Published 2025-01-01“…The first case was a 60-year-old man who have had mental status changes, fever, and progression of existing Parkinson's disease. Antibodies to WNV were present in cerebrospinal fluid (CSF). …”
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14232
Quantitative Analysis of Postural Instability in Patients with Parkinson’s Disease
Published 2021-01-01“…Postural instability is commonly observed in Parkinson’s disease, leading to an increasing risk of falling and worsening as the disease progresses. We found that limit of stability can be applied to reflect the dynamic evolution of postural instability in patients with Parkinson's disease. …”
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14233
The small modular molten salt reactor potential and opportunity in Saudi Arabia
Published 2025-02-01“…The adoption of MSRs presents an opportunity for groundbreaking research, economic diversification, and progression towards a sustainable energy future. With rising energy demands and the need to transition towards cleaner sources, nuclear energy is poised to play a vital role globally and in Saudi Arabia’s future energy mix. …”
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14234
Health-related quality of life outcomes reporting associated with FDA approvals in haematology and oncology
Published 2024-07-01“…Proportion of included trials that reported HRQoL, latency between FDA approval and first report of HRQoL data, HRQoL outcomes, and their correlation with OS (overall survival) and PFS (progression-free survival) were analysed.Results Of the 233 trials associated with 207 FDA approvals, HRQoL was reported in 50% of trials, of which only 42% had the data reported by the time of FDA approval. …”
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14235
Did selective kinase inhibitors change the management of patients with radioiodine-refractory thyroid cancer?
Published 2025-02-01“…Grade ≥3 adverse events occurred in 13 (42%) patients treated with lenvatinib and only in 1 (9%) patient treated with DT. Progression-free survival (PFS) and overall survival rates at 1 year were 72% and 83% in lenvatinib-treated patients and 69% and 83% in DT-treated patients, respectively. …”
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14236
Implementation of a value-based approach for older people who have suffered an acute myocardial infarction: study protocol
Published 2025-01-01“…Together with smartwatches, which will track important health aspects, and applications, this approach would enable older people to improve their health through correct lifestyle choices and their professional and informal caregivers to track their progress. With the use of the described technology and the multidisciplinary approach, the unmet needs and values of participants could be achieved. …”
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14237
Blood levels of cytokines highlight the role of inflammation in Alzheimer's disease
Published 2025-01-01“…Inflammation and angiogenesis have been defined as potential mechanisms associated with clinical progression from a cognitively normal state to Alzheimer's disease (AD). …”
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14238
Beyond buzzwords: fostering interdisciplinary and collaborative global health research in Germany and beyond
Published 2024-12-01“…Sustained, longer-term federal funding mechanisms will also be essential for ongoing progress.…”
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14239
Does Clostridium Perfringens Epsilon Toxin Mimic an Auto-Antigen Involved in Multiple Sclerosis?
Published 2025-01-01“…Multiple sclerosis (MS) is a chronic immune-mediated neurological disorder, characterized by progressive demyelination and neuronal cell loss in the central nervous system. …”
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14240
Organizational factors impacting the implementation of a digital mental health tool in Alberta's mental health care of youth and young adults
Published 2025-01-01“…This qualitative study explores organizational barriers and facilitators surrounding the implementation of a digital platform (Innowell), which uses measurement-based care (MBC) to track youth progress and outcomes. Data was collected from 154 mental health care providers participating in 23 focus groups across Alberta, drawing on school and community settings, specialized mental health services, and primary care networks. …”
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