Robotic Systems for Hand Rehabilitation—Past, Present and Future by Bogdan Gherman, Ionut Zima, Calin Vaida, Paul Tucan, Adrian Pisla, Iosif Birlescu, Jose Machado, Doina Pisla

“…<b>Conclusions:</b> While substantial progress has been made in recent years, several challenges persist, including missing information or incomplete data from source papers and a limited number of clinical studies to evaluate device effectiveness. …”
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SELP+ TEC:CD8+ T cell crosstalk associates with improved radiotherapy efficacy in cervical cancer by Qingyu Huang, Wenhui Yang, Fuhao Wang, Rui Huang, Qian Wang, Xiaohui Li, Tianyu Lei, Shengqin Yue, Wenxue Zou, Qi An, Jinbo Yue, Qinyong Hu, Chao Liu

“…Abstract P-selectin (SELP) expression in tumor cells has been implicated in promoting tumor progression and treatment resistance across various cancers. …”
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Therapeutic Effects of BCG Vaccination on Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Yu-Chen Chang, Chien-Ju Lin, Yu-Hsuan Hsiao, Yu-Han Chang, Shu-Jung Liu, Hsin-Yin Hsu

“…The Bacillus Calmette–Guerin (BCG) vaccine can modulate the immune response and decelerate disease progression. The aim of this study is to investigate the efficacy of the BCG vaccine for the treatment of T1DM. …”
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Cis‐Regulation of an m6A Eraser by an Insertion Variant Associated with Survival of Patients With Non‐Small Cell Lung Carcinoma by Lei Cheng, Qiangsheng Hu, Yanan Wang, Wei Nie, Haijiao Lu, Bo Zhang, Genming Zhao, Shiyun Ding, Feng Pan, Yinchen Shen, Runbo Zhong, Ruoxin Zhang

“…Abstract N6‐methyladenosine (m6A) serves as one of the crucial RNA modifications for genes involved in cancer progression. Here, 7273 expression quantitative trait loci potentially regulating 30 m6A pathway genes are identified from the GTEx database, with 69 single nucleotide polymorphisms significantly associated with survival of non‐small cell lung carcinoma (NSCLC) patients (n = 1523) from the ongoing genome‐wide association study after false positive probability tests. …”
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Evaluating translational science knowledge gains following an online short course for a general scientific audience by Amanda L. Vogel, Shadab F. Hussain, Jessica M. Faupel-Badger

“… Abstract Purpose: The translational science workforce requires preparation in both core skills for biomedical research and competencies for advancing progress along the translational pipeline. Delivering this content in a highly accessible manner will help expand and diversify the workforce. …”
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Parkinson’s Disease Prediction: An Attention-Based Multimodal Fusion Framework Using Handwriting and Clinical Data by Sabrina Benredjem, Tahar Mekhaznia, Abdulghafor Rawad, Sherzod Turaev, Akram Bennour, Bourmatte Sofiane, Abdulaziz Aborujilah, Mohamed Al Sarem

“…Background: Neurodegenerative diseases (NGD) encompass a range of progressive neurological conditions, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), characterised by the gradual deterioration of neuronal structure and function. …”
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Oscillometry reference values for children and adolescents by Christoph Valach, Emiel F. M. Wouters, Alina Ofenheimer, Pasquale Pio Pompilio, Alessandro Gobbi, Marie-Kathrin Breyer, Sylvia Hartl, Chiara Veneroni, Tobias Mraz, Caspar Schiffers, Otto Chris Burghuber, Ahmad Karimi, Christoph Gross, Charles Irvin, Robab Breyer-Kohansal

“…Results Reference equations for all oscillometry parameters were created for Caucasian children aged 6 to 17 years with a height span from 101 to 183 cm and a lung volume span from 1.7 to 8.8 L TLC. R and Z values progressively decrease and X values increase with increasing height. …”
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AdipoR1 enhances the radiation resistance via ESR1/CCNB1IP1/cyclin B1 pathway in hepatocellular carcinoma cells by Yuhan Gan, Linhui Zhu, Yimo Li, Ruoting Ge, Jiahe Tian, Yuxin Chen, Xiang He, Shumei Ma, Xiaodong Liu

“…We found that AdipoR1 promoted the translocation of ESR1 from the cytoplasm to the nucleus, and ESR1 inhibited the transcription of CCNB1IP1.Therefore, we propose that AdipoR1 regulates the ubiquitination level, cell cycle progression, and radiation resistance of HCC cells through the “AdipoR1 /ESR1/CCNB1IP1/cyclin B1” axis. …”
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DeepGlioSeg: advanced glioma MRI data segmentation with integrated local-global representation architecture by Ruipeng Li, Yuehui Liao, Yueqi Huang, Xiaofei Ma, Guohua Zhao, Yanbin Wang, Chen Song

“…IntroductionGlioma segmentation is vital for diagnostic decision-making, monitoring disease progression, and surgical planning. However, this task is hindered by substantial heterogeneity within gliomas and imbalanced region distributions, posing challenges to existing segmentation methods.MethodsTo address these challenges, we propose the DeepGlioSeg network, a U-shaped architecture with skip connections for continuous contextual feature integration. …”
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Bioelectronic osteosynthesis plate to monitor the fracture bone healing using electric capacitive variations by Diogo G. Pires, Nuno M. Silva, A. Completo, Marco P. Soares dos Santos

“…Methods An innovative bioelectronic osteosynthesis plate, minimally customized from a fixation device used in clinical practice, was developed to monitor the bone-implant interface to effectively detect the progression of bone fractures stages. Our technology includes a network-architectured capacitive interdigitated system, a Bluetooth module, an analog-to-digital converter, a multiplexer, a microcontroller, and a miniaturized battery. …”
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Global burden of colorectal cancer: epidemiology, risk factors by E. A. Medvedeva, G. G. Maryin, A. A. Leshchenko, M. V. Chernogorova, M. B. Dolgova, D. A. Nazarov, S. A. Ivanov

“…The practitioner needs to be aware of the risk factors leading to CRC and the various stages of disease progression in order to recommend appropriate screening strategies. …”
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Scapholunate advanced collapse of the wrist: a review by Nathalia A. Shchudlo, Shyngys K. Kuttygul, Artem R. Mironov

“…It is characterized by progressive deformity, instability and arthritis due to chronic dissociation of the scaphoid and lunate bones with chronic scapholunate interosseous ligament (SLIL) injuries. …”
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Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes in Advanced Melanoma Patients by Mélanie Saint-Jean, Anne-Chantal Knol, Christelle Volteau, Gaëlle Quéreux, Lucie Peuvrel, Anabelle Brocard, Marie-Christine Pandolfino, Soraya Saiagh, Jean-Michel Nguyen, Christophe Bedane, Nicole Basset-Seguin, Amir Khammari, Brigitte Dréno

“…Therapeutic responses included a complete remission, a partial remission, 2 stabilizations, and 6 progressions. Among these 4 patients with clinical benefit, 1 is still alive with 9 years of follow-up and 1 died from another cause after 8 years of follow-up. …”
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Using machine learning models to plan HIV services: Emerging opportunities in design, implementation and evaluation by T Dzinamarira, E Mbunge, I Chingombe, D F Cuadros, E Moyo, I Chitungo, G Murewanhema, B Muchemwa, G Rwibasira, O Mugurungi, G Musuka, H Herrera

“… HIV/AIDS remains one of the world’s most significant public health and economic challenges, with approximately 36 million people currently living with the disease. Considerable progress has been made to reduce the impact of HIV/AIDS in the past years through successful multiple HIV/AIDS prevention and treatment interventions. …”
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An Intriguing Case of Multisystem Inflammatory Syndrome in an Adult Patient with Remote Infection with COVID-19 and Acute Chlamydia by Madhuri Chandnani, William A. Charini, Anil Jha, Chetan Dodhia, Eduardo Haddad

“…A 27-year-old male patient presented with acute epididymitis secondary to acute Chlamydia infection that progressed to multisystem inflammatory failure with respiratory failure requiring endotracheal intubation and mechanical ventilation, cardiogenic shock with heart failure, and gastrointestinal and renal dysfunction. …”
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Ichthyoarchaeological perspectives on roles of fish and red meat during Indus Civilization in Gujarat, India by G. S. Abhayan, Pramod P. Joglekar, Pramod P. Joglekar, P. Ajithprasad, S. V. Rajesh, Pankaj Goyal, Brad Chase, Jeevan Kharakwal, Prabodh Shirvalkar

“…The roles of animals during the Indus Civilization (circa 4000 BCE to 1300 BCE), which thrived in South Asia, have been extensively studied by zooarchaeologists. While significant progress has been made in understanding the domestication and hunting of mammals, information on the use of aquatic organisms such as fish, mollusks, and crustaceans has been relatively sparse. …”
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Economic consequences of the phenomenon of uberization on the example of the services of selected carriers in the transport industry by Nina Stępnicka, Grygorii Monastyrskyi, Beata Sadowska, Robert Walasek, Paulina Wiączek, Grzegorz Zimon

“…The purpose of the study was to determine the impact of the progressive phenomenon of uberization on the competitiveness of the transportation industry in the pre-pandemic period and in the post-pandemic period. …”
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The immune-related gene CD5 is a prognostic biomarker associated with the tumor microenvironment of breast cancer by Yi Zhao, Hengheng Zhang, Wenwen Wang, Guoshuang Shen, Miaozhou Wang, Zhen Liu, Jiuda Zhao, Jinming Li

“…Abstract The occurrence and progression of breast cancer (BCa) are complex processes involving multiple factors and multiple steps. …”
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Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington’s Disease by Cristine de Paula Nascimento-Castro, Ana Claudia Wink, Victor Silva da Fônseca, Claudia Daniele Bianco, Elisa C. Winkelmann-Duarte, Marcelo Farina, Ana Lúcia S. Rodrigues, Joana Gil-Mohapel, Andreza Fabro de Bem, Patricia S. Brocardo

“…This study investigated whether chronic administration of the antioxidant probucol improved motor and affective symptoms as well as hippocampal neurogenic function in the YAC128 transgenic mouse model of HD during the early- to mild-symptomatic stages of disease progression. The motor performance and affective symptoms were monitored using well-validated behavioral tests in YAC128 mice and age-matched wild-type littermates at 2, 4, and 6 months of age, after 1, 3, or 5 months of treatment with probucol (30 mg/kg/day via water supplementation, starting on postnatal day 30). …”
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Coculture with Eastern oysters is unlikely to reduce OsHV-1 impacts to farmed Pacific oysters: A modelling approach by Familusi Oluwatosin Adekunle, Gorka Bidegain, Tal Ben-Horin

“…Simulation results indicated that introducing C. virginica did not impede OsHV-1 progression; even in the M. gigas/C. virginica 10/90 system, M. gigas mortality reached its maximum, albeit delayed by approximately 10 days. …”
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