Governance and poverty eradication policy performance during the NRM1 Administration in Uganda 1986 – 2020 by Mucunguzi, Abel, Bwengye, Katabaazi Anny

“…The idea behind this research is that if the causes of the slow progress in poverty reduction are not identified and targeted holistically through policy and inculcation of good governance at all levels of government administration, it will be difficult for Uganda to achieve significant poverty reduction and eradication in the long run. …”
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Assessing the Hydraulic Performance of Ntungamo Town Piped Water Distribution System. by Ahimbisibwe, James

“…Water distribution networks are crucial for regional development, as they serve multiple purposes beyond providing water for human consumption, directly influencing a nation's progress. Reliable water supply, a key component of these networks, plays a vital role in sustaining and improving public quality of life. …”
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Urbanisation and Education Development: A Case Study of Rock High School. by Abaho, Derick

“…Additionally, upgrading infrastructure and monitoring progress through data-driven evaluations are crucial for adapting to ongoing changes.…”
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University Governing Council Report 2019/20 - 2023/24 by Kabale University

“…The University’s growing staff and student numbers are presented as indicators of its progress. It is evident from the report that the number of publications and research is increasing. …”
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Influence of Parents’ Socio-Economic Status on Pupils’ Academic Performance in Primary Schools of Kabale Municipality by Wilberforce, Nabaasa

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Trifluridine-tipiracil in previously treated patients with oestrogen receptor-positive, HER2-negative metastatic breast cancer (BOOG 2019-01 TIBET trial): a single-arm, multicentre... by Niels A.D. Guchelaar, Ron H.J. Mathijssen, Maaike de Boer, Marlies L. van Bekkum, Joan B. Heijns, Birgit E.P.J. Vriens, Mandy M. van Rosmalen, Lonneke W. Kessels, Lisanne Hamming, Karin J. Beelen, Peter Nieboer, Susan M. van den Berg, Esther Oomen-de Hoop, Rhodé M. Bijlsma, Monique E.M.M. Bos

“…The participants received trifluridine-tipiracil 35 mg/m2 orally twice a day on days 1–5 and days 8–12 during a 28-day cycle until disease progression, unacceptable toxicity, or withdrawal of consent. …”
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First-line chemotherapy with selective internal radiation therapy for intrahepatic cholangiocarcinoma: The French ACABi GERCOR PRONOBIL cohort by Nicolas Adamus, Julien Edeline, Julie Henriques, Nadim Fares, Thierry Lecomte, Anthony Turpin, Dewi Vernerey, Mathilde Vincens, Brice Chanez, David Tougeron, Christophe Tournigand, Eric Assenat, Matthieu Delaye, Sylvain Manfredi, Olivier Bouché, Nicolas Williet, Angelique Vienot, Lorraine Blaise, Léo Mas, Cindy Neuzillet, Alice Boilève, Gaël S. Roth

“…The primary outcome was progression-free survival (PFS). Secondary outcomes were overall survival (OS), objective response rate (ORR) and tumor resection rate. …”
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A phase 2, double-blind, placebo-controlled trial of a valproate/lithium combination in ALS patients by M.-C. Boll, M. Alcaraz-Zubeldia, C. Rios, D. González-Esquivel, S. Montes

“…Conclusions: Combined VPA-Li treatment associated with slower ALS progression and better secondary outcomes. This dual treatment overcame the futility threshold and merits further investigation in ALS. …”
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A phase 2, double-blind, placebo-controlled trial of a valproate/lithium combination in ALS patients by M.-C. Boll, M. Alcaraz-Zubeldia, C. Rios, D. González-Esquivel, S. Montes

“…Conclusions: Combined VPA-Li treatment associated with slower ALS progression and better secondary outcomes. This dual treatment overcame the futility threshold and merits further investigation in ALS. …”
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Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma by Zihao Deng, Lixia Liu, Guantai Xie, Zhenming Zheng, Jieyou Li, Wenchong Tan, Yaotang Deng, Jinxin Zhang, Manfeng Liang, Yingxia Wu, Zhifeng Zhou, Yan Li, Yukui Chen, Yaling Huang, Hairou Su, Guibing Wu, Xiongjie Shi, Shengpei Cen, Yandan Liao, Yilin Liu, Fei Zou, Xuemei Chen

“…Excessive lipid accumulation promotes the occurrence and progression of hepatocellular carcinoma (HCC), accompanied by high levels of fatty acid synthetase (FASN) and more active lipogenesis. …”
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Epidemiological characteristics of elderly osteoporosis fractures and their association with air pollutants: a multi-center study in Hebei Province by Guangzhao Hou, Qian Xiao, Zhipeng Ye, Shihang Liu, Shuai Zhou, Yan Wang, Wenjing Li, Yingze Zhang, Hongzhi Lv

“…The number of hospitalized patients increased progressively from 2019 to 2022. The Distribution Lag Nonlinear Model (DLNM) showed that the cumulative lagged effects of PM2.5 and PM10 on the number of hospitalized elderly osteoporosis fracture patients exhibited a bimodal distribution, with the Relative Risk (RR) reaching its peak at a 1-day lag (PM2.5: RR = 1.032, 95% CI: 1.019, 1.045; PM10: RR = 1.022, 95% CI: 1.014, 1.029). …”
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From skyscrapers to sky savers: how New York City’s Local Law 97 advances climate resilience and public health by Ethan Chervonski, Ethan Chervonski, Marisa A. Guerrero, William N. Rom, William N. Rom

“…Local Law 97 (LL97) is the latest in NYC’s long trajectory of climate action initiatives, setting progressively stringent caps on greenhouse gas (GHG) emissions from large buildings greater than 25,000 square feet. …”
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Environmental Disinfection Based on Mobile Intelligent Networking Highly Efficient Ultraviolet Light Machines by Chun-Yen Chung, Wen-Tsai Sung, Lin-Chi Wang, Lailatus Siami, John Paul Santos

“…In this way, the disinfection progress could be updated at anytime, anywhere and the current disinfection status in the classroom could be displayed in real-time, allowing teachers and students on campus to carry out teaching and learning in a safe and secure environment.…”
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Do indigenous people get left behind? An innovative methodology for measuring the unmeasurable economic conditions and poverty from the poorest region of Luzon, Philippines by Emmanuel A. Onsay, Jomar F. Rabajante

“…The study underscores the urgency of targeted policies and programs to address multidimensional deprivations faced by Indigenous communities, emphasizing the importance of data-driven approaches in improving welfare and promoting equitable socio-economic progress. Other researchers worldwide could replicate, reproduce, or reuse the suggested methods to assist indigenous peoples in reducing poverty and enhancing their well-being. …”
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Engineered CAF-cancer cell hybrid membrane biomimetic dual-targeted integrated platform for multi-dimensional treatment of ovarian cancer by Yuwei Yao, Jiarui Zhang, Kexin Huang, Yingying Peng, Shuangshuang Cheng, Shuangge Liu, Ting Zhou, Jinhua Chen, Haojia Li, Yingchao Zhao, Hongbo Wang

“…Abstract Background The efficacy of current therapies for ovarian cancer is limited due to the multilevel and complex tumor microenvironment (TME), which induces drug resistance and tumor progression in a single treatment regimen. Additionally, poor targeting and insufficient tissue penetration are important constraints in ovarian cancer treatment. …”
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Injectable Tumoricidal Neural Stem Cell-Laden Hydrogel for Treatment of Glioblastoma Multiforme—An In Vivo Safety, Persistence, and Efficacy Study by Jasmine L. King, Alain Valdivia, Shawn D. Hingtgen, S. Rahima Benhabbour

“…Despite efforts to advance treatment, GBM remains treatment resistant and inevitably progresses after first-line therapy. Induced neural stem cell (iNSC) therapy is a promising, personalized cell therapy approach that has been explored to circumvent challenges associated with the current GBM treatment. …”
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Understanding how older people with mild frailty engage with behaviour change to support their independence: a qualitative study by Benjamin Gardner, Louise Marston, Kate R Walters, Vari M Drennan, Rachael Frost, Paul Chadwick, Rebecca L Gould, Yolanda Barrado-Martin, Sarah Gibson, Rekha Elaswarapu, Rashmi Kumar, Kalpa Kharicha, Tasmin Alanna Rookes, Christina Avgerinou, Jane Hopkins, Jessica Catchpole, Claire Jowett

“…Interviews explored participation experiences, including engagement, perceived progress and impact. Transcripts were analysed using thematic analysis.Results Key themes included frailty symptoms and adapting/compensating for these, self-efficacy and beliefs about capacity or need for change, familiarity with goal-setting processes and health-related knowledge, accessibility of services and outdoor environments, and enabling social support. …”
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Understanding the properties and functional role of neutrophils in oral squamous cell carcinoma – A systematic review by Thayalan Dineshkumar, Nirmala Anandan, Krishnan Rajkumar, Indumathi N

“…All the included studies showed that neutrophils play a crucial role in cancer progression and the prognosis of the patient. The analyses showed that neutrophils play a significant role in adverse OS, DFS, and DSS in HNSCC, which can serve as a cost-effective prognostic biomarker to help stratify patients and individualize treatments. …”
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Epigenetic modifications in bladder cancer: crosstalk between DNA methylation and miRNAs by Wei Li, Wei Li, Wei Li, Peiyue Luo, Peiyue Luo, Peiyue Luo, Qi Chen, Qi Chen, Qi Chen, Le Cheng, Le Cheng, Le Cheng, Lifeng Gan, Lifeng Gan, Lifeng Gan, Fangtao Zhang, Fangtao Zhang, Fangtao Zhang, Haidong Zhong, Haidong Zhong, Haidong Zhong, Liying Zheng, Biao Qian, Biao Qian

“…With the robust development of epigenetics, the crucial role of epigenetic modifications in the occurrence and progression of BC has been elucidated. These modifications not only affect gene expression but also impact critical biological behaviors of tumor cells, including proliferation, differentiation, apoptosis, invasion, and metastasis. …”
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Anaemia and Iron Homeostasis in a Cohort of HIV-Infected Patients: A Cross-Sectional Study in Ghana by Christian Obirikorang, Razak Gyesi Issahaku, Derick Nii Mensah Osakunor, James Osei-Yeboah

“…In this study population, HIV-associated anaemia is common and is related to HAART status and disease progression. HIV itself is the most important cause of anaemia and treatment of HIV should be a priority compared to iron supplementation.…”
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