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Transcription factor TCF4: structure, function, and associated diseases
Published 2024-11-01“…The biological role of approximately 20 % of human proteins has not been established yet, and the molecular functions of the known part of the proteome remain poorly understood. This hinders progress in basic and applied biological and medical sciences, especially in treating hereditary diseases, which are caused by mutations and polymorphic variants in individual genes. …”
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13322
Impact of Personal Values on School Engagement Among Chinese Adolescents: Mediating Effects of Achievement Goals
Published 2025-01-01“…Much of past research has centered on the impact of personal values on career progression. Yet, the connection between personal values and academic performance remains under-explored, especially the mechanisms through which they relate. …”
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Insights into stem Batomorphii: A new holomorphic ray (Chondrichthyes, Elasmobranchii) from the upper Jurassic of Germany.
Published 2025-01-01“…This highlights that, despite considerable progress in our understanding of the diversity and phylogeny of early rays, difficulties remain in establishing robust relationships within batomorphs. …”
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13324
Spatio-temporal patterns of the construction and development of urban open spaces in Macau from 1889–2020
Published 2025-02-01“…This study investigates the spatiotemporal evolution of urban open spaces in Macau from 1889 to 2020, aiming to uncover the historical progression of Macau’s urban landscape. The research hypothesizes that Macau’s urban open space development is inversely related to its socio-economic advancement, with a notable shift from abundant open spaces to increased built-up areas. …”
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13325
LANGUAGE SPACE OF NEURAL NETWORKS: FEATURES AND DIFFERENCES FROM NATURAL LANGUAGE
Published 2024-12-01“…This allows for the accumulation of experience and the ability to think with insights, which are essential for AI to progress beyond its current limitations.…”
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Laboratory biomarkers for multiple sclerosis and their role in clinical practice
Published 2023-11-01“…Levels of glial fibrillary acidic protein in cerebrospinal fluid and blood serum can help distinguish primary progressive MS from the relapsing-remitting course of this disease. …”
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Novel pathogenically oriented surgical technique for advanced glaucoma
Published 2020-03-01“…Adequate intraocular pressure (IOP) lowering slows the progression of glaucomatous optic neuropathy and preserves vision. …”
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COVID-19 vaccine hesitancy and vaccine passports: a cross-sectional conjoint experiment in Japan
Published 2022-06-01“…Objectives While the development of vaccines against the Novel Coronavirus (COVID-19) brought hope of establishing herd immunity and ending the global pandemic, vaccine hesitancy can hinder the progress towards herd immunity. In this study, by analysing the data collected when citizens undergo public health restrictions due to the pandemic, we assess the determinants of vaccine hesitancy, reasons for hesitation and potential effectiveness of vaccine passports used to relax public health restrictions on mitigating vaccine hesitancy.Design Cross-sectional study, longitudinal study and conjoint experimental design.Setting An online survey conducted in Japan in July 2021.Participants A demographically representative sample of 5000 Japanese adults aged 20–74.Primary outcome measures COVID-19 vaccination intentionResults We found that about 30% of respondents did not intend to get vaccinated or had not yet decided, with major reasons for vaccine hesitancy relating to concerns about the safety and side effects of the vaccine. …”
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Rehabilitation of an Upper Extremity Weight-Bearing Athlete with an Ulnar Collateral Ligament Injury: A Case Report
Published 2024-08-01“…Rehabilitation consisted of therapeutic exercise for the progression of UE functional weight-bearing including planks, ball push-ups, handstands, crab walks, stool pulls, handstand walks, and UE plyometric jumps…”
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REVIEWING ADVANCEMENT IN TELECOMMUNICATIONS INFRASTRUCTURE: A COMPARATIVE STUDY OF AFRICA AND THE USA
Published 2024-02-01“…The findings of this study contribute to the global understanding of the diverse approaches to telecommunications infrastructure development and highlight areas where collaboration and knowledge exchange between Africa and the USA can further accelerate progress. As the world becomes increasingly interconnected, the lessons learned from these regions can inform strategies for addressing connectivity challenges and fostering inclusive technological development on a global scale.…”
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Une stratégie de développement fondée sur l’innovation
Published 2013-01-01“…Aujourd’hui, l’entreprise est une importante PMI internationale de l’industrie des articles de sport, portée par des produits tels que les lampes frontales, les harnais d’escalade et les engins mécaniques assurant la progression sur corde. Hier, elle était une simple entreprise artisanale familiale, proposant du matériel de spéléologie. …”
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KYNU as a Biomarker of Tumor-Associated Macrophages and Correlates with Immunosuppressive Microenvironment and Poor Prognosis in Gastric Cancer
Published 2023-01-01“…KYNU-overexpressing macrophages drove GC progression through unique ligand-receptor pairs and transcription factors and were associated with adverse clinical phenotypes in GC. …”
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EKONOMINĖS IR KULTŪRINĖS VERTYBĖS: PANAŠUMAI IR SKIRTUMAI
Published 2004-01-01“…In spite of this, there is no doubt concerning the importance of cultural values for the spiritual and social progress of both an individual and society. Furthermore, cultural values form the ,,culture capital“ itself, without which it is difficult to imagine even creation and increase of economical capital of society. …”
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