Design and Validation of the Scientific-Research Skills Questionnaire for Basic Education Teachers by Gilber Chura-Quispe, Bianca Daisa Laura-De-La-Cruz, Patricia Rosa María Nué Caballero, Edith Cristina Salamanca Chura, Héctor Octavio Guido Torres Orihuela

“… One teacher skill that has allowed for progress and development in pedagogy is that of scientific research, but there is very little attention to its measurement in basic education. …”
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Danshen injection ameliorates unilateral ureteral obstruction-induced renal fibrosis by inhibiting ferroptosis via activating SIRT1/GPX4 pathway by Yiwen Cao, Huan Zhao, Shuyin Lin, Junqi Chen, Jingli Xiong, Zhijun Zeng, Ziyu Long, Yingru Su, Yingqi Zhong, Lingru Zhao, Mingshan Zhang, Junbiao Wu, Yuan Zhou, Jiuyao Zhou

“…However, whether DSI slows the progression of renal fibrosis or the potential mechanism is uncertain.MethodsWe investigated renal fibrosis models using UUO mice and TGF-β stimulation in HK-2 cells.ResultsOur findings revealed that DSI or Fer-1 alleviated kidney injury by ameliorating renal morphology injury and pathological injury in vivo. …”
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Extender Supplementation with Glutathione (GSH) and Taurine Improves In Vitro Sperm Quality and Antioxidant Status of New Zealand Rabbits during Chilled Storage for up to 72 hours by Mohamed F. F. Bayomy, Sobhy E. Hassab El-Nabi, Tahany A. El Kassas, Zeinab I. Attia, Ayman M. Saeed, Heba S. A. Taha, Mahmoud Alagawany, Livio Galosi, Lucia Biagini, Seham El-Kassas

“…Nonsupplemented samples were used as a control. Sperm’s progressive motility, acrosome reaction, and extracellular oxidative stress biomarkers such as MDA contents and GPx, SOD, and CAT concentrations and intracellular transcriptomic levels of SOD and CAT genes were assessed. …”
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Adjuvant Autologous Melanoma Vaccine for Macroscopic Stage III Disease: Survival, Biomarkers, and Improved Response to CTLA-4 Blockade by Michal Lotem, Sharon Merims, Stephen Frank, Tamar Hamburger, Aviram Nissan, Luna Kadouri, Jonathan Cohen, Ravid Straussman, Galit Eisenberg, Shoshana Frankenburg, Einat Carmon, Bilal Alaiyan, Shlomo Shneibaum, Zeynep Ozge Ayyildiz, Murat Isbilen, Kerem Mert Senses, Ilan Ron, Hanna Steinberg, Yoav Smith, Eitan Shiloni, Ali Osmay Gure, Tamar Peretz

“…Thirty-five patients, who received an autologous vaccine, followed by ipilimumab for progressive disease, had a significantly improved 3-year survival of 46% compared with 19% in nonvaccinated patients treated with ipilimumab alone (p=0.007). …”
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Sustainable methodical approaches to recycling sludge waste: value-added products, and their agricultural applications by Abas Siraj Hamda, Tesfaye Kassaw Bedru, Mani Jayakumar, Workisa Bacha Garuma

“…Research Highlights • Emerging investigation on recycling sludge waste to value added end products has been addressed • Progressive methods on sludge management have been articulated • Pros, cons and limitations of various sludge management practices were also addressed • Agricultural applications of value added products obtained from sludge have been discussed …”
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Implementing technical training models to enhance basic volleyball skills in students by Yuni Astuti, Erianti Erianti, Haripah Lawanis, Bekir Erhan Orhan, Karuppasamy Govindasamy, Al Ikhlas

“…This study investigates the application of various technical training models, including skill-based drills, progressive skill-building techniques, and individualized feedback systems, to improve students' performance in essential volleyball techniques. …”
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Retrospective Analysis of the Efficacy and Safety of Ultrasound-Guided Radiofrequency Ablation in the Treatment of Papillary Thyroid Microcarcinoma: A Follow-Up Study of Continuous... by Gongli Zhou, Xuefeng Zhang, Ke Xu, Beibei Zhang, Ruiqing Su, Tingting Cai, Wei Zhao, Feng Li

“…The efficacy of ultrasound-guided RFA was evaluated by measuring the tumor volume reduction rate (VRR), tumor disappearance rate, and disease progression in 358 patients with low-risk unifocal PTMC who underwent ultrasound-guided RFA at Hangzhou Weja Hospital, while the safety was evaluated by measuring their complications. …”
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A lectin produced by a Streptomyces species targets mammalian pancreatic acinar cells in mice and humans by Janine C. Quijano, Honoka Natsuyama, Alonso Tapia, Karine Bagramyan, Jose A. Ortiz, Jacob Mares, Markus Kalkum, Yoko Fujita-Yamaguchi, Hsun Teresa Ku

“…We focused on the normal pancreas in this study because glycans on pancreatic cells have been associated with initiation and progression of pancreatic cancer, a deadly disease. …”
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The S4G-WISE View of Global Star Formation in the Nearby Universe by M. E. Cluver, T. H. Jarrett, D. A. Dale, J.-D. T. Smith, M. J. I. Brown, W. van Kempen, E. Lengerer, R. Incoll, C. Davey, R. Holloway, J. Cameron, K. Sheth

“…Finally, we use our derived SFR prescriptions to examine the location of galaxies in the log SFR–log M _stellar plane, as a function of morphological type, which underscores the complexity of dust-derived properties seen in galaxies of progressively earlier type.…”
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Baicalin: a potential therapeutic agent for acute kidney injury and renal fibrosis by Xiaoming Li, Xiaoming Li, Rui Xu, Rui Xu, Dan Zhang, Ji Cai, Ji Cai, He Zhou, He Zhou, Tao Song, Tao Song, Xianyao Wang, Xianyao Wang, Qinghong Kong, Liujin Li, Zhaohui Liu, Zhixu He, Zhengzhen Tang, Jun Tan, Jidong Zhang, Jidong Zhang, Jidong Zhang

“…This review aims to summarize Baicalin’s progress in these areas, including its molecular mechanism, application in treatment, and absorption, distribution, metabolism, and excretion. …”
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Neuroprotective effects of curculigoside against Alzheimer’s disease via regulation oxidative stress mediated mitochondrial dysfunction in L-Glu-exposed HT22 cells and APP/PS1 mice... by Wenqi Wang, Yidi Qu, Siyu Li, Jinyu Chu, Hongxin Yang, Lirong Teng, Di Wang

“…In APP/PS1 mice, 4-week CCG administration significantly improved their memory and behavioral impairments, enhanced the function of cholinergic system, reduced the deposition of Aβ and neurofibrillary fiber tangles caused by tau phosphorylation, and suppressed the development and progression of oxidative stress in brains of APP/PS1 mice. …”
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Assessment of Quality of Life in Patients with Parkinson's Disease by Freddy Fernando Jumbo Salazar, Carlos Alejandro Troya Altamirano, Daniela Abigail Cobo Álvarez

“…<strong>Foundation:</strong> parkinson's disease is a chronic progressive disorder of the nervous system that mainly affects motor coordination and movement control. …”
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Patient-derived follicular lymphoma spheroids recapitulate lymph node signaling and immune profile uncovering galectin-9 as a novel immunotherapeutic target by Cèlia Dobaño-López, Juan García Valero, Ferran Araujo-Ayala, Ferran Nadeu, Fabien Gava, Carla Faria, Marine Norlund, Renaud Morin, Pascale Bernes-Lasserre, Fabian Arenas, Marta Grau, Cristina López, Irene López-Oreja, Neus Serrat, Ares Martínez-Farran, Lluís Hernández, Heribert Playa-Albinyana, Rubén Giménez, Silvia Beà, Elías Campo, Jean-Michel Lagarde, Armando López-Guillermo, Laura Magnano, Dolors Colomer, Christine Bezombes, Patricia Pérez-Galán

“…Abstract Follicular lymphoma (FL), the most common indolent non-Hodgkin lymphoma, constitutes a paradigm of immune tumor microenvironment (TME) contribution to disease onset, progression, and heterogenous clinical outcome. Here we present the first FL-Patient Derived Lymphoma Spheroid (FL-PDLS), including fundamental immune actors and features of TME in FL lymph nodes (LNs). …”
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How Much Time Should Be Waited and What Are the Main Findings to Evaluate the Hepatocellular Carcinoma Response to Regorafenib? A Real-Life Experience by Gustavo Hideki Kawanami, Leopoldo Katsuda, Thiara Barcelos Rocha, Fabio da Silva Yamashiro, Leonardo Pelafsky, Xingshun Qi, Fernando Gomes Romeiro

“…Since he had no signs of liver dysfunction and suffered tumor progression during sorafenib treatment, regorafenib was initiated. …”
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Parameters Controlling the Oxide Reduction during Sintering of Chromium Prealloyed Steel by Monika Hrubovčáková, Eva Dudrová, Eduard Hryha, Margita Kabátová, Jarmila Harvanová

“…Temperature intervals of oxide reduction processes during sintering of the Fe-3%Cr-0.5%Mo prealloyed powder using continuous monitoring of processing-exhaust gas composition (CO, CO2, and H2O) were identified and interpreted in relation to density (6.5–7.4 g/cm3), sintering temperature (1120 and 1200°C), heating and cooling rates (10 and 50°C/min), carbon addition (0.5/0.6/0.8%), type (10%H2-N2, N2), and purity (5.0 and 6.0) of the sintering atmosphere. The progress in reduction processes was evaluated by oxygen and carbon contents in sintered material and fracture strength values as well. …”
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Liver lobes and cirrhosis: Diagnostic insights from lobar ratios by Kriti Pandey, Debabrata Dash, Raj Kumar Koiri

“…Alcohol, viral hepatitis, and non-alcoholic fatty liver disease are the most common cause of cirrhosis. Cirrhosis progresses from the compensated stage to the decompensated stage. …”
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The triterpenoids-enriched extracts from Antrodia cinnamomea mycelia attenuate alcohol-induced chronic liver injury via suppression lipid accumulation in C57BL/6 mice by Yange Liu, Ronglong Chen, Lanzhou Li, Ruitao Dong, Hui Yin, Yawen Wang, Anhui Yang, Jianbin Wang, Changtian Li, Di Wang

“…Combining with the pathological observations, ACT displayed an anti-steatosis effects to restrain the progress of ALD. Based on proteomic analysis and enzyme-linked immunosorbent assay, ACT had been confirmed to regulate the levels of lipid biogeneration-related factors and depressed the over-accumulation of hepatic reactive oxygen species. …”
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Prospective Randomized Study Comparing Combined Phaco-ExPress and Phacotrabeculectomy in Open Angle Glaucoma Treatment: 12-Month Follow-Up by Joanna Konopińska, Marta Deniziak, Emil Saeed, Agnieszka Bartczak, Renata Zalewska, Zofia Mariak, Marek Rękas

“…The presence of additional implant (as is the case of the ExPress mini glaucoma shunt implantation) may cause progressive loss of endothelial cells.…”
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Design and Optimization of the Circulatory Cell-Driven Drug Delivery Platform by Pengyu Gao, Dan Zou, Ansha Zhao, Ping Yang

“…Although nanoparticle-based drug delivery systems have made great progress in extending circulation time, improving durability, and controlling drug release, the targeting efficiency remains low. …”
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NADH Reductive Stress and Its Correlation with Disease Severity in Leigh Syndrome: A Pilot Study Using Patient Fibroblasts and a Mouse Model by Tamaki Ishima, Natsuka Kimura, Mizuki Kobayashi, Chika Watanabe, Eriko F. Jimbo, Ryosuke Kobayashi, Takuro Horii, Izuho Hatada, Kei Murayama, Akira Ohtake, Ryozo Nagai, Hitoshi Osaka, Kenichi Aizawa

“…This precise method for NADH measurement is expected to outperform conventional assays, such as those for lactate, providing a simpler and more reliable means of assessing disease progression.…”
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