Six events that shaped antibody approvals in oncology by Suman Paul, Suman Paul, Shibin Zhou, Shibin Zhou

“…While the use of ADC and BsAb formats and the current rapid pace of approvals appear routine and almost inevitable, such progress was thought to be quite improbable in the early days of therapeutic antibody development. …”
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The Role of Macrophages in the Pathogenesis of Celiac Disease by A. I. Khavkin, E. V. Loshkova, E. I. Kondratieva, N. S. Shapovalova, I. R. Grishkevich, I. V. Doroshenko, G. N. Yankina

“…Studying the involvement of macrophages at different stages of celiac disease progression is important for the development of new treatments for this disease.…”
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Radiation Therapy with Concurrent Chemotherapy for Locally Advanced Cervical Carcinoma: Outcome Analysis with Emphasis on the Impact of Treatment Duration on Outcome by Juan Diaz, Daohai Yu, Bizhan Micaily, J. Stuart Ferriss, Enrique Hernandez

“…In multivariable analyses we only found ORT to be statistically significant predictor for progression-free survival (PFS) and overall survival (OS) (HR [95% CI] for non-ORT vs. …”
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Comprehensive review of mapping climate change impacts on tea cultivation: bibliometric and content analysis of trends, influences, adaptation strategies, and future directions by Altyeb Ali Abaker Omer, Altyeb Ali Abaker Omer, Chun-Hua Zhang, Chun-Hua Zhang, Jie Liu, Jie Liu, Zhi-guo Shan, Zhi-guo Shan

“…The results show significant progress in understanding the physiological, biochemical, and molecular responses of tea plants to climate-induced stressors, including antioxidant mechanisms, secondary metabolite regulation, and genomic adaptations. …”
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Stimuli-responsive hydrogel dressing for wound healing by Wei Zhang, Jun Hu, Hao Wu, Xiufei Lin, Limei Cai

“…Finally, summarize stimulus-responsive wound dressings on the basis of active research challenges, current research progress, and development trends in the field.…”
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A Reduction in Selenoprotein S Amplifies the Inflammatory Profile of Fast-Twitch Skeletal Muscle in the mdx Dystrophic Mouse by Craig Robert Wright, Giselle Larissa Allsopp, Alex Bernard Addinsall, Natasha Lee McRae, Sofianos Andrikopoulos, Nicole Stupka

“…There is interest in characterising novel genes that regulate inflammation due to their potential to modify disease progression. Gene polymorphisms in Selenoprotein S (Seps1) are associated with elevated proinflammatory cytokines, and in vitro SEPS1 is protective against inflammatory stress. …”
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Development and Characterization of Mikania, Kapok, Wool, Sugarcane, and Pineapple Fiber Reinforced Polyester Composite by Rafid Anan, Hasan Al Mahmud, Tabriz Ahnaf Khan, Md Sakib Ul Alam Sakib, Md Shahadhat Hossain

“…The discoveries present hopeful possibilities for additional examination and progression in composite materials, consequently advancing the development of sustainable materials.…”
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A prospective observational study on asymptomatic bacteriuria in pregnancy & its effects on maternal & perinatal outcome by K. Mounika, Pramila Gupta, Parveen Yousuff

“…Conclusion: Asymptomatic bacteriuria if left untreated will progress into symptomatic urinary tract infections and pyelonephritis which have an adverse maternal and fetal outcome. …”
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Comparing Personality Traits and Resilience Among Treatment-Seeking and Treatment-avoidant Elderly with Health Anxiety Disorde by Masood Ghorbanalipour, Somayeh Hajihatamlou, Bahare Hosseinlou, Ameneh Zardi Nahr

“…Introduction: Treatment-seeking behaviors in elderly patients can facilitate timely diagnosis and effective intervention for health issues, whereas treatment-avoidant behaviors may contribute to the progression of diseases and an increased burden of chronic conditions. …”
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A novel dynamic machine learning-based explainable fusion monitoring: application to industrial and chemical processes by Husnain Ali, Rizwan Safdar, Yuanqiang Zhou, Yuan Yao, Le Yao, Zheng Zhang, Weilong Ding, Furong Gao

“…The complexity and fusion dynamism of the modern industrial and chemical sectors have been increasing with the rapid progress of IR 4.0–5.0. The transformative characteristics of Industry 4.0–5.0 have not been fully explored in terms of the fundamental importance of explainability. …”
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Profile of intestinal fungal microbiota in acute pancreatitis patients and healthy individuals by Meng-Qi Zhao, Miao-Yan Fan, Meng-Yan Cui, Su-Min Chen, Jing-Jing Wang, Ying-Ying Lu, Qiao-Li Jiang

“…Conclusion Our study provides the first empirical evidence that AP patients have different fecal fungal microbiota, which raises the possibility that mycobiota contribute to the etiology and progression of AP.…”
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Epigenetic regulation of the nuclear genome associated with mitochondrial dysfunction in Leber’s hereditary optic neuropathy (LHON) by Aswathy P. Nair, Ambika Selvakumar, Janani Gopalarethinam, B. Abishek Kumar, Balachandar Vellingiri, Mohana Devi Subramaniam

“…This finding indicates that these modifications might mitigate the impact of LHON mutations on complex 1 and aid in elucidating the mechanism underlying the progression of LHON disease.…”
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Ponatinib alleviates non-alcoholic steatohepatitis through TFEB-mediated autophagy by Zhuomiao Lin, Meiqing Yang, Xihui Yu, Guozhu Tan, Jiahong Zhong

“…ObjectiveNon-alcoholic steatohepatitis (NASH) is a progressive liver disease with lipid accumulation, inflammation, and liver fibrosis. …”
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RSK4 promotes the metastasis of clear cell renal cell carcinoma by activating RUNX1-mediated angiogenesis by Jing Ma, Yanru Yang, Kaijing Wang, Jin Liu, Junyi Feng, Gongcheng Wang, Shuangping Guo, Linni Fan

“…Notably, renal cell carcinoma (RCC) is rich in blood vessels; therefore, this study aimed to explore the biological function of RSK4 in ccRCC progression and its specific regulatory mechanism. We analyzed changes in the expression of target genes through transcriptomic and proteomic assessments. …”
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TB prevention activities in the WHO European Region by A. Matteelli, Z. Mkrtchyan, T. Masini, A. Hovhannesyan, G. Kuchukhidze, S. Ahmedov, P. Kerndt, L. Rossi, A. Yedilbayev, D. Falzon, A. Dadu

“…BACKGROUND: TB preventive treatment (TPT) is the primary available healthcare intervention to reduce the risk of progression from TB infection to TB disease. The WHO Regional Office for Europe established the European Prevention and Systematic Screening Initiative to End TB (PASS) to scale up activities related to the programmatic management of TPT. …”
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The abnormal flow behavior of Mg-9Gd-4Y-2Zn-0.5Zr alloy during hot tensile deformation at high temperature and low strain rate by Mu Meng, Xiaoying Wang, Jinbiao Zhang, Xingxing Chen, Genxing Lei, Zhaoming Yan, Zhimin Zhang

“…Under high-temperature and low-strain-rate conditions (450°C-0.0001s⁻1, 500°C-0.001s⁻1, and 500°C-0.0001s⁻1), the alloy exhibits excellent plasticity with elongation exceeding 300%, and stress progressively increases with strain in later deformation stages. …”
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Success Stories of Multilingual Literacy: A Case Study of Ife 1970 Nigeria’s Project and the 2002 Western Cape’s LOITASA’s Project in South Africa by Modupe Grace Aroge, Leketi Makalela, Peter Merisi

“…In a progressively interrelated world, the advancement of strong multilingual literacy skills among learners is of great importance. …”
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The multifaceted anti-atherosclerotic properties of herbal flavonoids: A comprehensive review by Meiwen Huang, Xuena Xie, Rong Yuan, Qiqi Xin, Shudong Ma, Hongai Guo, Yu Miao, Chunyu Hu, Yizhun Zhu, Weihong Cong

“…Atherosclerosis (AS) is a major etiological factor underpinning a spectrum of cardiovascular diseases, leading to cerebral infarction, coronary artery disease, and peripheral vascular disease. The chronic progression of AS, spanning from initial plaque formation to the occurrence of acute cardiovascular events, underscores the complexity of AS and the challenges it presents in terms of treatment. …”
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Characterizing the agroecological transition of Italian farming systems using FADN database by Sarah Stempfle, Simone Russo, Vincenzo Fiore, Ruggiero Sardaro, Piermichele La Sala, Luigi Roselli

“…The findings provide a knowledgebase for developing targeted policies and monitoring progress in agroecological transition. The study confirms the viability of using the FADN to evaluate the degree of agroecological transition, while also revealing information gaps. …”
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Evaluation and Immunolocalization of BMP4 and FGF8 in Odontogenic Cyst and Tumors by Neeti Swarup, Meghanand T. Nayak, Zoya Chowdhary, Monica Mehendiratta, Shikha Khatana, Su Jung Choi, Chandarani Sagolsem

“…The expression of BMP4 and FGF8 corelates well with the proliferative component of the pathologies, indicating a possible role in the pathogenesis and progression.…”
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