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12761
p38δ MAPK: Emerging Roles of a Neglected Isoform
Published 2014-01-01“…In summary, while our knowledge of p38δ MAPK has progressed somewhat since its identification in 1997, our understanding of this particular isoform in many cellular processes still strikingly lags behind that of its counterparts.…”
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12762
Phytochemical Profiles and Anticancer Effects of Calophyllum inophyllum L. Extract Relating to Reactive Oxygen Species Modulation on Patient-Derived Cells from Breast and Lung Canc...
Published 2023-01-01“…Overall, our findings highlight the anticancer potential of C. inophyllum extract, emphasize its ability to modulate cellular ROS levels and target key molecular pathways involved in cancer progression. This study sheds light on the promising therapeutic implications of C. inophyllum extract as a novel agent for cancer treatment, which is safe for normal cells.…”
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12763
Grid-Integrated Dual Wind Turbine System Using SEPIC Converter with Whale Optimized PI Controller
Published 2025-02-01“…Main objectives of the study are to progress a dual independent doubly fed induction generator (DFIG)-based wind energy conversion system (WECS) for stable and efficient power delivery to an AC microgrid while ensuring grid stability and compliance with power quality standards. …”
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12764
Coinfection of Herpes Simplex virus 2 and Mycobacterium chelonae in acute hydrops associated with keratoconus: A case report
Published 2025-01-01“…Posteriorly, she developed dendritic epithelial lesions suggestive of Herpes Simplex virus infection. These lesions progressed, leading to a central corneal infiltrate and descemetocele. …”
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12765
Establishment of performance parameters for the Qubit™ 1X dsDNA HS Assay for use in forensic genetics casework
Published 2025-07-01“…This study has advanced our progression towards implementing a molecular autopsy sequencing workflow in South Africa and provides the first performance parameters for the Qubit™ 1X dsDNA HS Assay Kit which may be useful for other laboratories.…”
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12766
Self-induced optical non-reciprocity
Published 2025-01-01“…Exciting experimental progress has been achieved by either introducing spatial-temporal modulation of the optical medium or combining Kerr-type optical nonlinearity with spatial asymmetry in photonic structures. …”
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12767
Upregulation of α3β1-Integrin in Podocytes in Early-Stage Diabetic Nephropathy
Published 2016-01-01“…Podocyte injury plays an important role in the onset and progression of diabetic nephropathy (DN). Downregulation of α3β1-integrin expression in podocytes is thought to be associated with podocyte detachment from the glomerular basement membrane, although the mechanisms remain obscure. …”
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12768
VaSe-MRP: Velocity-aware and stability-estimation–based multi-path routing protocol in flying ad hoc network
Published 2019-11-01“…In routing maintenance progress, a path similarity and path remaining survival duration–based multi-path selection mechanism is proposed. …”
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12769
Relationship between neutropenia caused by nanoliposomal irinotecan/fluorouracil/leucovorin and treatment outcomes in the NAPOLEON-2 study (NN-2301)
Published 2025-01-01“…The primary endpoint was overall survival (OS), and the secondary endpoints were overall response rate, progression-free survival (PFS), and relative dose intensity. …”
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12770
Clinical Significance of ErbB Receptor Family in Urothelial Carcinoma of the Bladder: A Systematic Review and Meta-Analysis
Published 2012-01-01“…The overall risks of disease progression for patients with EGFR or ErbB2 overexpression were 4.5 (95% CI: 2.5–8.4) and 1.1 (95% CI: 0.6–1.9), and the risks of mortality were 3.0 (95% CI: 1.6–5.9) and 1.1 (95% CI: 1.0–1.2), respectively. …”
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12771
Management of adult patients with alcoholic liver disease: clinical guidelines of the Russian Scientific Liver Society
Published 2018-08-01“…The alcoholic liver disease (ALD) is a clinical and morphological entity that encompasses several forms of the liver parenchyma lesions resulting from alcohol abuse, that range from steatosis to alcoholic hepatitis (steatohepatitis) followed by progression to fibrosis, liver cirrhosis and hepatocellular carcinoma. …”
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12772
TransDeep: Transformer-Integrated DeepLabV3+ for Image Semantic Segmentation
Published 2025-01-01“…In recent years, image semantic segmentation algorithms have made significant progress driven by deep learning technology, and are widely used in fields such as medical image analysis, assistive technology for the visually impaired people, and autonomous driving. …”
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12773
ACD-ML: Advanced CKD detection using machine learning: A tri-phase ensemble and multi-layered stacking and blending approach
Published 2025-01-01“…It is extremely important to slow down the progression of kidney deterioration to prevent kidney dialysis or transplant. …”
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12774
Young men’s barriers to and facilitators of utilising HIV-testing services in South Africa
Published 2025-01-01“…They are also unlikely to start and adhere to antiretroviral therapy until the virus has progressed to advanced AIDS stages. Objectives: To explore young men’s barriers to and facilitators of accessing and utilising HTS at the rural Driefontein and peri-urban Steadville Township in Ladysmith, KwaZulu-Natal (KZN) province, and to develop a comprehensive framework of care for young men to encourage and support them to utilise HTS at primary healthcare facilities. …”
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12775
Lymphoid Progenitor Cells from Childhood Acute Lymphoblastic Leukemia Are Functionally Deficient and Express High Levels of the Transcriptional Repressor Gfi-1
Published 2013-01-01“…Acute lymphoblastic leukemia (ALL) is the most frequent malignancy of childhood. Substantial progress on understanding the cell hierarchy within ALL bone marrow (BM) has been recorded in the last few years, suggesting that both primitive cell fractions and committed lymphoid blasts with immature stem cell-like properties contain leukemia-initiating cells. …”
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12776
Synthesis of Mesoporous ZnO•SiO2 Nanocomposite from Rice Husk for Enhanced Degradation of Organic Substances Including Janus Green B under Visible Light
Published 2024-10-01“…The effects of operating parameters on the photo-degradation reaction progress, including catalyst dosage, initial dye concentration, and pH of the initial dye were investigated in detail. …”
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12777
Construct Validity and Psychometric Properties of Farsi Version of the Motivational Persistence Scale in University Students
Published 2024-02-01“…The results related to the correlation between aspects of motivational persistence with positive and negative progress emotions and self-efficacy beliefs provided evidence in defense of the criterion validity of this scale. the internal consistency coefficients of the subscales the long-term purposes pursuing, current purpose pursuing and recurrence of unattained purposes subscales was 0/90, 0/89 & 0/87 . …”
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12778
Neuron-Specific Fluorescence Reporter-Based Live Cell Tracing for Transdifferentiation of Mesenchymal Stem Cells into Neurons by Chemical Compound
Published 2017-01-01“…In vitro monitoring of MSCs along the time courses showed progressive increase of fluorescence till 30 h after treatment, corresponding with the increase in neurite length. …”
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12779
Proportions of Proinflammatory Monocytes Are Important Predictors of Mortality Risk in Hemodialysis Patients
Published 2017-01-01“…Despite the continuous progression in dialysis medicine, mortality and the burden of cardiovascular disease (CVD) among hemodialysis patients are still substantial. …”
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12780
An Ultra-Wide Range D-Shaped Fiber SPR Sensor with a Nanostructure of Gold–MoS<sub>2</sub> and Sodium for the Simultaneous Measurement of Refractive Index and Temperature
Published 2025-01-01“…These results are essential for progress in simultaneously detecting RI and T.…”
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