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12621
A study of maternal and perinatal outcomes in primigravida and multigravida by comparing their partogram in labor
Published 2025-01-01“…Conclusion: Partograph can be used to assess the progress of labor and to identify when intervention is necessary. …”
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12622
The Kab Quarterly Newsletter: Issues 8/2024 Graduation Edition.
Published 2024“…As well, we are pleased to observe that the University’s Governing Council and Top Management have been vigilant in steering the University in a progressive strategic direction. This is done through a variety of research, teaching, and learning activities. …”
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12623
The KAB Quarterly Newsletter. Issue 8 | 2024 Graduation Edition.
Published 2024“…As well, we are pleased to observe that the University’s Governing Council and Top Management have been vigilant in steering the University in a progressive strategic direction. This is done through a variety of research, teaching, and learning activities. …”
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12624
The KAB Quarterly Newsletter. Issue 8 | 2024 Graduation Edition.
Published 2024“…As well, we are pleased to observe that the University’s Governing Council and Top Management have been vigilant in steering the University in a progressive strategic direction. This is done through a variety of research, teaching, and learning activities. …”
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12625
Commercial Banks and Socio Economic Wellbeing of the People: A case study of Equity Bank Kabale Branch.
Published 2020“…The study further recommends that the Commercial Banks should introduce and those that have maintain and upgrade the information technology to capture and control the history and progress on the loans that have been given out so as to reduce on the default rates of these commercial Banks The study also recommends that Banks should use Credit Reference Bureau as it provides information about the credit history of clients seeking facilities from the Bank.…”
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12626
The prognostic value of the platelet-to-lymphocyte ratio in multiple myeloma patients treated with a bortezomib-based regimen
Published 2025-01-01“…The results showed that patients in the low-PLR group had significantly worse OS (P = 0.00031) and progression-free survival (PFS) (P < 0.0001) compared to those in the high-PLR group. …”
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12627
Proteomic analysis of murine norovirus-infected Raw 264.7 cells reveals the induction of Ras GTPases
Published 2025-01-01“…LC–MS analysis was employed for label-free shotgun proteomics on the host cell proteomes. The progression of MNV infection status was monitored using an immunofluorescence-conjugated noroviral capsid protein VP1 and a confocal microscope. …”
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12628
Impact of thermal variation on the naupliar development of the copepod Apocyclops spartinus (Ruber, 1968) (Copepoda: Cyclopidae), under controlled conditions
Published 2025-02-01“…Results indicated a progressive increase in development time by reducing temperature from 24 to 20 ºC (1.75 times) and 20 to 16 ºC (4 times). …”
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12629
Factors affecting hematological abnormality in HIV-infected patients at Dr. Wahidin Sudirohusodo Hospital Makassar, Indonesia
Published 2024-09-01“…Introduction Human immunodeficiency virus (HIV) is characterized by a progressive damage of immune system, resulting in a number of opportunistic infections and hematological abnormalities, and become more severe in late stages. …”
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12630
Proinflammatory Cytokines IL-6 and TNF-α Increased Telomerase Activity through NF-κB/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells
Published 2017-01-01“…Our data suggest that withaferin A could be a promising anticancer agent that effectively inhibits the progression of colorectal cancer.…”
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12631
Turn TRAIL Into Better Anticancer Therapeutic Through TRAIL Fusion Proteins
Published 2025-01-01“…Conclusion This work focuses on the progress in recombinant TRAIL fusion proteins and aims to provide more rational and effective fusion strategies to enhance the efficacy of recombinant soluble TRAIL, facilitating its translation from bench to bedside as an effective anti‐cancer therapeutic.…”
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12632
CLN-978, a novel half-life extended CD19/CD3/HSA-specific T cell-engaging antibody construct with potent activity against B-cell malignancies with low CD19 expression
Published 2023-08-01“…Background Despite significant progress in the development of T cell-engaging therapies for various B-cell malignancies, a high medical need remains for the refractory disease setting, often characterized by suboptimal target levels.Methods To address this issue, we have developed a 65-kDa multispecific antibody construct, CLN-978, with affinities tuned to optimize the killing of low-CD19 expressing tumor cells. …”
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12633
Pityriasis versicolor: insight into current knowledge and treatment possibilities
Published 2025-01-01“…Conclusion: Despite significant progress in understanding and managing pityriasis versicolor, further research is essential. …”
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12634
Association of high organochlorine pesticide serum levels with oxidative stress in intestinal metaplasia and gastric cancer
Published 2025-01-01“…Our results showed that progression from functional dyspepsia towards intestinal metaplasia and gastric cancer was associated with elevations in organochlorine pesticide serum levels, which had an association with the induction of oxidative stress and the reduction of antioxidant and acetylcholine esterase enzyme activities.…”
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12635
Study on gene expression in the liver at various developmental stages of human embryos
Published 2025-01-01“…Despite this, the essential genes, biological processes, and signal pathways that drive liver development in human embryos remain poorly understood.MethodsIn this study, liver samples were collected from human embryos at progressive developmental stages, ranging from 2-month-old to 7-month-old. …”
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12636
Measurement and influencing factors of urban waterfront street vitality from the perspectives of behavior and perception
Published 2025-01-01“…Serving as the direct interface for interaction between the waterfront and urban dwellers, the street space environment significantly influences people’s living experiences and social interactions. Despite progress in the renovation and development of waterfront streets, these areas remain underutilized and lack the vitality expected of such locations. …”
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12637
Effect of N-Feruloylserotonin and Methotrexate on Severity of Experimental Arthritis and on Messenger RNA Expression of Key Proinflammatory Markers in Liver
Published 2016-01-01“…Rheumatoid arthritis (RA) is a chronic inflammatory disease, leading to progressive destruction of joints and extra-articular tissues, including organs such as liver and spleen. …”
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12638
Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes
Published 2025-01-01“…IntroductionRecombinant alpha-1 antitrypsin (AAT) therapy has been shown to have beneficial effects to mitigate the progression of various diseases. Here, we hypothesized that administration of pharmaceutical-grade human AAT (hAAT) is effective in mitigating hypertension induced by salt-loading in juvenile mice by reducing the concentration of diacylglycerols (DAGs) and activity of protein kinase C (PKC) in the kidney.MethodsFour-week old 129Sv mice were salt-loaded to induce hypertension and then administered hAAT or vehicle.ResultsAdministration of hAAT was found to significantly reduce high blood pressure in both the active and inactive cycles of the 129Sv hypertensive mice. …”
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12639
Exosomes Regulate the Transformation of Cancer Cells in Cancer Stem Cell Homeostasis
Published 2018-01-01“…It is well known that these cells communicate with each other and thereby regulate the progression of the tumor. Recent studies have provided evidence that exosomes mediate the interactions between different types of cells in the tumor microenvironment, providing further insight into how these cells interact through exosome signaling. …”
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12640
The impact of environmental fees to taxes on total factor productivity of manufacturing enterprises: empirical evidence from China
Published 2025-01-01“…Additionally, while effective management practices have a positive moderating effect, financing constraints hinder this progress. (3) the impact of the TEPFT on TFP is particularly pronounced in state-owned enterprises and in provinces where tax rates are elevated.…”
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