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Targeting ferroptosis: opportunities and challenges of mesenchymal stem cell therapy for type 1 diabetes mellitus
Published 2025-02-01“…Abstract Type 1 diabetes mellitus (T1DM) is characterized by progressive β-cell death, leading to β-cell loss and insufficient insulin secretion. …”
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Regulation of modular Cyclin and CDK feedback loops by an E2F transcriptionoscillator in the mammalian cell cycle
Published 2011-03-01“…Our model shows that the cell cycle progression as well as the checkpoints of the cell cycle can be understood through the interactions between the main E2F feedback loop and the driven Cyclin feedback loops.Multiple models were proposed for the cell cycle dynamics; each with differing basic mechanisms. …”
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The ADDIE Model in Instructional Design: NUST MISIS Case Study
Published 2023-10-01“…The article gives insight into course description, structure and principles which reflect the coherent progress of Design, Development and Implementation stages. …”
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Robson classification to assess caesarean section in nulliparous women
Published 2023-10-01“…According to the Robson classifications, the most significant indications of CS were maternal request and failure of progress. The average gestational was 39.51±1.13 weeks. …”
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TAS-102 Monotherapy and Combination Therapy with Bevacizumab for Metastatic Colorectal Cancer
Published 2021-01-01“…Extracted data include median overall survival (mOS), median progression-free survival (mPFS), and the incidence of adverse events for meta-analysis. …”
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The Pivotal Immunomodulatory and Anti-Inflammatory Effect of Histone-Lysine N-Methyltransferase in the Glioma Microenvironment: Its Biomarker and Therapy Potentials
Published 2021-01-01“…EZH2 forms a repressive chromatin structure which eventually participates in regulating the development as well as lineage propagation of stem cells and glioma progression. Posttranslational modifications are distinct approaches for the adjusted modification of EZH2 in the development of cancer. …”
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COVID-19 Pandemisinin Diş Hekimliği Hastaları Üzerine Etkisinin Path Analizi Kullanılarak Değerlendirilmesi
Published 2023-06-01“…Background: During the pandemic, which continues all over the world and progresses in Turkey, it is a priority to understand patients’ knowledge level concerning this contagious disease and understand patients’ attitude during their dental problems and also level of anxiety that could cause misbehavior. …”
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Microimaging Characterization of a B16-F10 Melanoma Metastasis Mouse Model
Published 2006-04-01“…To determine if the time progression, extent, and metabolism of melanoma metastases could be monitored noninvasively, serial micro-CT and small-animal PET imaging studies were performed by using a mouse model of melanoma. …”
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Insights into the dependence of post-stroke motor recovery on the initial corticospinal tract connectivity from a computational model
Published 2025-01-01“…In contrast, if the residual CST connectivity is insufficient, hand/arm dexterity barely recovers, even as the phases of stroke progress. Instead, the functional upregulation of the reticulospinal tract (RST) often occurs. …”
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Use of ultra-freezers of -152 °c as a viable alternative to liquid nitrogen in storing
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