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12261
Beyond Current Frontiers of Electrocatalysis
Published 2025-01-01“…One of the key reasons why the transition to renewable energy sources is progressing slowly is the low efficiency of processes at electrified interfaces where electricity is converted and stored as chemical energy. …”
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12262
Efficacy and safety of laquinimod versus placebo in relapsing-remitting multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials
Published 2025-02-01“…Results The meta-analysis of four randomized controlled trials including 3665 patients found that laquinimod significantly reduced the annualized relapse rate compared with placebo (mean difference = −0.08, 95% confidence interval [CI] = −0.12, −0.04, I 2 = 0%). For disability progression confirmed at 3 months, laquinimod provided a significant advantage over placebo (hazard ratio [HR] = 0.75, 95% CI = 0.59, 0.96, I 2 = 25%), whereas no benefit was achieved at 6 months (HR = 0.69, 95% CI = 0.45, 1.06, I 2 = 66%). …”
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12263
Novel approaches in myelofibrosis
Published 2024-12-01“…Abstract Myelofibrosis (MF) is a clonal myeloid neoplasm characterized by bone marrow fibrosis, splenomegaly, and disease‐associated symptoms, as well as increased mortality, due to thrombosis, severe bleeding, infections, or progression to acute leukemia. Currently, the management of MF patients is tailored according to risk scores, with higher‐risk (intermediate‐2 and high‐risk) patients being assessed for allogeneic stem cell transplantation, which remains the only potentially curative treatment option. …”
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12264
Pregnancy Followed by Delivery May Affect Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels in Women of Reproductive Age
Published 2012-01-01“…We conclude that pregnancy followed by delivery may delay the beginning and progress of arteriosclerosis and its clinical manifestations in women of reproductive age.…”
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12265
Unraveling Incongruence: The EU Proposal in the Belgrade-Pristina Dialogue
Published 2024-11-01“…The paper argues that the EU’s strategy, which emphasizes informal agreements and seeks to avoid overt confrontation, may yield eventual progress but also risks entrenching political tensions within Serbia and Kosovo. …”
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12267
Circular RNAs as a novel class of potential therapeutic and diagnostic biomarkers in reproductive biology/diseases
Published 2024-12-01“…CircRNAs are integral pieces in multiple cellular functions, including moving substances within the nucleus, silencing one X chromosome, cell death, the ability of stem cells to differentiate into different cell types, and the process of gene expression inherited from parental genes. Due to the progress made in high-speed gene sequencing, a large amount of circRNA molecules have been detected, revealing their significant functions in diverse biological functions like enhancing testicular development, preserving the differentiation and renewal of spermatogonial cells, and controlling spermatocyte meiosis. …”
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12268
Potential Functions and Causal Associations of GNLY in Primary Open-Angle Glaucoma: Integration of Blood-Derived Proteome, Transcriptome, and Experimental Verification
Published 2025-01-01“…However, the mechanisms by which these loci contribute to POAG progression remain unclear. This study aimed to identify potential causative genes involved in the development of POAG.Methods: We utilized multi-dimensional high-throughput data, integrating proteome-wide association study(PWAS), transcriptome-wide association study (TWAS), and summary data-based Mendelian randomization (SMR) analysis. …”
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12270
An Integrated Bearing Fault Diagnosis Method Based on Multibranch SKNet and Enhanced Inception-ResNet-v2
Published 2024-01-01“…With the help of deep learning, we can fully extract the deep features hidden in the data, significantly improving the accuracy and efficiency of fault diagnosis. Despite this progress, deep learning still faces two outstanding problems. (1) Each layer uses the same convolution kernel to extract features, making it difficult to adaptively select convolution kernels based on the features of the input image, which limits the network’s adaptability to different input features and leads to weak feature extraction. (2) Large number of parameters and long training time. …”
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12271
Multi-target regulatory effects of rhaponticin in a rat model of hepatic fibrosis revealed by non-targeted metabolomics
Published 2025-01-01“…IntroductionHepatic fibrosis (HF), a progressive chronic liver disease, is a serious threat to global public health. …”
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Pursuing a corporate sustainable identity: Green governance strategy, hybrid vehicle development, knowledge and sustainability performance
Published 2025-03-01“…The automobile industry's transition toward sustainability remains impeded by inconsistent green governance, which hampers progress in hybrid vehicle production. Existing literature predominantly focuses on technological innovation and consumer adoption, often overlooking the governance structures that foster environmental responsibility. …”
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Institutional Challenges in the Laws of Iran\'s 2025 Vision Document and Subordinate Plans
Published 2024-06-01“…Results: Consequently, an effective and dependable system for measurement and evaluation becomes imperative to assess and monitor progress in the realization of long-term visions and plans. …”
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12279
Lymphatic filariasis in Zambia: A scoping review protocol.
Published 2023-01-01“…<h4>Background</h4>Zambia is among the countries making major progress in limiting cases of the neglected tropical disease lymphatic filariasis on the path to reaching global elimination targets. …”
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12280
Huaqiao Nongchang: Isolated Settlements of Overseas Chinese Inside China
Published 2024-01-01“…A comprehensive analysis of works by Chinese experts uncovers a significant reason for the PRC authorities' adoption of this approach: it provided a swift solution to hunger-related issues and the employment of vast refugee populations.As time progressed, drawbacks in this approach to managing emigrants became apparent. …”
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