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12121
Expression analysis of transforming growth factor beta (TGF-β) in oral squamous cell carcinoma
Published 2024-03-01“…Objective: The most widely seen cancer in the neck and head portion is oral squamous cell carcinoma (OSCC), which is reported in more than 45 % of cases in some countries. Although much progress has been made to control OSCC in recent years, therapies for OSCC remain challenging. …”
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12122
Burden of disease attributable to high body mass index in Belgium: a comparative risk assessment analysis
Published 2025-01-01“…The increasing concern about the health and economic burden of BMI makes it essential for countries to track their progress on major modifiable risk exposures. The aim of the study is to estimate the burden attributable to high BMI in Belgium, in terms of years of life lost due to disability (YLD), years of life lost due to premature mortality (YLL) and disease costs, using comparative risk assessment. …”
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12123
Global research landscape and hotspots for ferroptosis in glioma: A comprehensive bibliometric and visual analysis
Published 2025-02-01“…Studying ferroptosis is crucial for understanding the mechanisms underlying the onset and progression of glioblastoma, identifying therapeutic targets, and improving prognosis assessment and diagnostic methods. …”
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12124
AxonFinder: Automated segmentation of tumor innervating neuronal fibers
Published 2025-01-01“…Neurosignaling is increasingly recognized as a critical factor in cancer progression, where neuronal innervation of primary tumors contributes to the disease's advancement. …”
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12125
Ultrasound diagnostics of traumatic pancreatitis at combined trauma
Published 2014-08-01“…In patients of the second group signs of acute pancreatitis were revealed at 2–3 week on a background of progressing multiorgan failure.Conclusions. Traumatic pancreatitis in patients with combined trauma develops both due to direct damage of the pancreas, and as a result of developing multiorgan failure. …”
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12126
The Imbalance of FOXP3/GATA3 in Regulatory T Cells from the Peripheral Blood of Asthmatic Patients
Published 2018-01-01“…Treg cells play an important role in the pathogenic progress of asthma. Objective. To address the alterations of Treg cells in asthma. …”
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12127
Achieving Hepatitis C Micro-Elimination in Chinese Injecting Drug Users: A Dynamic Network Modeling Study
Published 2024-12-01“…Methods This study utilized models based on dynamic social networks to simulate HCV transmission and disease progression among people who inject drugs in China, incorporating a cost-effectiveness analysis from a healthcare perspective. …”
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12128
Context effects on repair of 5′‐overhang DNA double‐strand breaks induced by Cas12a in Arabidopsis
Published 2024-10-01“…Abstract Sequence‐specific endonucleases have been key to the study of the mechanisms and control of DNA double‐strand break (DSB) repair and recombination, and the availability of CRISPR‐Cas nucleases over the last decade has driven rapid progress in the understanding and application of targeted recombination in many organisms, including plants. …”
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12129
Estimation of genetic parameters for visual score traits: a simulation study
Published 2025-02-01“…However, evaluation groups of more than 40 animals should be used to obtain greater accuracy and genetic progress. …”
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12130
Atrioventricular Conduction Delay in the Second Trimester Measured by Fetal Magnetocardiography
Published 2014-01-01“…None of the fetuses progressed to a more advanced heart block. Conclusion. …”
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12131
Cytokine and Chemokine Profile in Patients with Multiple Myeloma Treated with Bortezomib
Published 2020-01-01“…A total of 71 MM patients were examined: 41 with primary refractory disease (17) or early relapse (28), and 30 who were bortezomib sensitive with no progression for at least six months. Patients who demonstrated CR or PR after bortezomib-based therapies longer than six months after treatment discontinuation were designated bortezomib sensitive. …”
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12132
Impact of Underweight after Treatment on Prognosis of Advanced-Stage Ovarian Cancer
Published 2014-01-01“…A total of 360 patients with stage III-IV epithelial ovarian cancer were enrolled and divided into three groups by body mass indexes (BMIs): underweight (BMI < 18.5 kg/m2); normal weight to overweight (18.5 kg/m2 BMI < 27.5 kg/m2); obesity (BMI ≥ 27.5 kg/m2). Progression-free survival (PFS), overall survival (OS), CA-125, and neutrophil to lymphocyte ratio (NLR) as a marker reflecting host inflammation and immunity were compared among the three groups according to the three treatment times: at diagnosis; after surgery; and after treatment. …”
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12133
Combination of Human Leukocyte Antigen and Killer Cell Immunoglobulin-Like Receptor Genetic Background Influences the Onset Age of Hepatocellular Carcinoma in Male Patients with He...
Published 2013-01-01“…Our findings also suggest an important role of natural killer cells (or other KIR-expressing cells) in the progress of HBV-related HCC development.…”
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12134
Psychological, psychiatric, and behavioral sciences measurement scales: best practice guidelines for their development and validation
Published 2025-01-01“…Methodologists and researchers have criticized current scale development practices, emphasizing that inaccurate measurements can derail theory development and clinical decisions, thereby impeding progress in mental health research and practice. These shortcomings often stem from a lack of understanding of appropriate scale development techniques. …”
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12135
Tuberculosis Mimicking-Musculoskeletal Tumor of The Hand: An Uncommon Case of Extrapulmonary Tuberculosis
Published 2023-10-01“…Histopathological examination and culture are needed to confirm the diagnosis. Conclusions: Slow progression and multiple differential diagnoses frequently result in a delayed diagnosis, which leads to complications. …”
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12136
Integrative bioinformatics and immunohistochemical analysis unravel the prognostic significance and immunological implication of LIMCH1 in breast cancer: a retrospective study
Published 2025-01-01“…The functional annotations revealed pathways related to carcinogenesis and metabolic reconfiguration, thus suggesting the role of LIMCH1 in tumour progression. Additionally, LIMCH1 expression was correlated with an immunosuppressive TIME characterized by increased numbers of M2 macrophages and reduced numbers of CD8 + T cells and NK cells. …”
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12137
TRα1 mutant suppresses KLF9 to cause endometrial metaplasia with ectopic IL-33 expression leading to uterine fibrosis and infertility
Published 2025-01-01“…Histologically, there was progressive uterine atrophy in Thra1PV/+ mutant mice, characterized by squamous metaplasia of the endometrial mucosa and endometrial fibrosis. …”
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12138
Synthesis and Validation of a Weatherproof Nursery Design That Eliminates Tropical Evening-Fever Syndrome in Neonates
Published 2014-01-01“…Hyperthermia can rapidly slow down baby’s progress and response to treatment. High sunlight intensity in tropical countries such as Nigeria manifests in incessant high neonatal temperatures towards early evenings. …”
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12139
DC-Based Immunotherapy Combined with Low-Dose Methotrexate Effective in the Treatment of Advanced CIA in Mice
Published 2015-01-01“…Combination therapy with low-dose MTX and type II collagen- (CII-) pulsed smDCs (CII-smDCs) was more effective in inhibiting disease progression than high or low-dose MTX alone or a combination of high dose MTX and CII-smDCs. …”
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12140
NASSDA as a Data-Collaborative Network to Enhance Social Science Research in East Asia
Published 2025-01-01“…Since the establishment of NASSDA in 2016, numerous challenges have impeded progress, including differences in infrastructure and systems for survey data loading, financial and personnel situations, national policies, and domestic circumstances. …”
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