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  1. 12041

    Successful Management of Thyrocervical Trunk Aneurysm Ruptured into the Thoracic Cavity After Cesarean Section in Nonstable Patient with Neurofibromatosis Type I by Nikola Mirković, Marko Prokić, Marija Novčić, Miloš Arsenijević, Snežana Sretenović, Dragan Knežević, Vojin Kovačević, Marija Šorak, Olivera Kostić

    Published 2024-12-01
    “…The patient, a 33-year-old woman with neurofibromatosis type I, three days after an already performed Cesarean section had acute pain in the left area of the neck, swelling, and a hematoma that progressed rapidly to respiratory distress, hemothorax, and hemorrhagic shock. …”
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  2. 12042

    TERT-TP53 mutations: a novel biomarker pair for hepatocellular carcinoma recurrence and prognosis by Jin Li, Ling Bai, Zhaodan Xin, Jiajia Song, Hao Chen, Xingbo Song, Juan Zhou

    Published 2025-01-01
    “…Furthermore, patients with both TERTpm and TP53m exhibited a significantly higher risk of tumor relapse (P < 0.05) and shorter progression-free survival (P < 0.05). Collectively, our results suggest that presence of both TERTpm and TP53m may serve as a robust predictor of tumor recurrence and a marker of poor prognosis in HCC.…”
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  3. 12043

    Cytokine/Chemokine/Growth Factor Profiles Contribute to Understanding the Pathogenesis of the Salivary Gland Dysfunction in Euthyroid Hashimoto’s Thyroiditis Patients by K. Morawska, M. Maciejczyk, S. Zięba, Ł. Popławski, A. Kita-Popławska, J. Krętowski, A. Zalewska

    Published 2021-01-01
    “…Furthermore, salivary IL-12 (p40) may be helpful in assessing the progression of autoimmunity-related inflammation in the course of HT. …”
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  4. 12044

    Advancing the Fight Against Cervical Cancer: The Promise of Therapeutic HPV Vaccines by Qian Zheng, Misi He, Zejia Mao, Yue Huang, Xiuying Li, Ling Long, Mingfang Guo, Dongling Zou

    Published 2025-01-01
    “…Currently, there are no approved therapeutic HPV vaccines worldwide; however, active progress is being made in clinical research and development using multiple platforms such as peptides, proteins, DNA, RNA, bacterial vectors, viral vectors, and cell-based, each offering relative advantages and limitations for delivering HPV antigens and generating targeted immune responses. …”
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  5. 12045

    Downregulation of LncRNA SNHG7 Sensitizes Colorectal Cancer Cells to Resist Anlotinib by Regulating miR-181a-5p/GATA6 by Deng Pan, Kehe Chen, Ping Chen, Yu Liu, Yingying Wu, Jingning Huang

    Published 2023-01-01
    “…It has been reported that small nucleolar RNA hostgene 7 (SNHG7) can sponge microRNAs to regulate colorectal cancer (CRC) progression. Given its important regulatory role in cancer biology, we wondered whether SNHG7 is involved in drug resistance to anlotinib (ATB) in CRC. …”
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  6. 12046

    Up-and-down determination of prophylactic norepinephrine boluses combined with crystalloid co-load for preventing post-spinal anesthesia hypotension during cesarean section by Chengfei Xu, Peipei Zhang, Chunying Dai, Jingjun Zhang, Honghao Wu, Qianying Liu, Zhiqiang Zhang, Fengwei Yin, Huadong Ni, Liang Cheng

    Published 2025-01-01
    “…The dosages of norepinephrine were established employing the up-and-down sequential allocation technique, starting with 8 µg and progressively rising by 1 µg increments. The primary objective was to detect the effective dosage (ED90 and ED50) of norepinephrine necessary to avoid hypotension following spinal anesthesia. …”
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  7. 12047

    Mesothelioma and Radical Surgery 2 (MARS 2): protocol for a multicentre randomised trial comparing (extended) pleurectomy decortication versus no (extended) pleurectomy decorticati... by Liz Darlison, John Edwards, Apostolos Nakas, Nick A Maskell, Wendy Underwood, Chris Rogers, Matthew Callister, David Waller, Richard Milton, Victoria Ashford-Turner, Paul Taylor, Claire Matthews, Victoria Hughes, Kelvin Lau, Alan Kirk, Robert C Rintoul, Elizabeth A Stokes, Kate Ashton, Daisy Elliott, Rosie Harris, Marie Kirwan, Juliette Novasio, Sara Waplington, Eric Lim, Holly Mckeon, Charlotte Jacobs, Laura White, Mary O’Brien, Judith Moore, Louise Li, Nicola Mills, Sanjay Popat, Suzanne Miller, Nadia Yousaf, D A Fennell, Clinton Ali, Andrea Bille, Liz Fuller, Andreea Ionescu, Manjusha Keni, Pek Koh, Talal Mansy, Dakshinamoorthy Muthukumar, Tony Pope, Amy Roy, Riyaz Shah, Jonathan Shamash, Zacharias Tasigiannopoulos, Sarah Treece, Katherine Joyce, Barbara Warnes, Athanasia Gravani, Rachel Brophy, Nicola Farrar, Jane Elliott, Philip Noyes, Louise Nelson, Sara Tenconi, Laura Socci, Hilary Wood, Helena Hanratty, Helena Stanley, Robert Rintoul, Amy Gladwell, Jenny Castedo, Amanda Stone, Charlotte Ingle, Hayley Hewer, Eleanor Aynsley, Andrea Watson, Alison Hassall, Masuma Begum, Christopher Worth, Ellie Piggott, Elizabeth Nadin, Yvonne Summers, Raffaele Califano, Laura Cove-Smith, Matt Evison, Maria Blinston, Amal Ismail, Rachel Chant, Asmita Desai, Ian Morgan, Victoria Lake, Nichola Harris, Simon Hodge, Nadza Tokaca, Adam Januszewski, Avani Athauda, Anisha Ramessur, Emily Grist, Niamh Colman, Michael Flynn, Joan Joyce, Sarah Vaughan, Maria Piga, Derya Sahin, Agnieszka Yongue, Emma Turay, Jaishree Bhosle, Rajiv Kumar, Charlotte Milner-Watts, Jessica Brown, David Walder, Alexandros Georgiou, Xiaorong Wu, Naila Kaudeer, Kroopa Joshi, Michael Davidson, Shelize Khakoo, Bee Ayite, Kathryn Priest, James Dobbyn, Vasanthi Prathapan, Deborah McCrimmon, Natalie Ash, Alison Norton, Bianca Peet, Libby Hennessy, Rosemary Johnson

    Published 2020-09-01
    “…Secondary outcomes include health-related quality of life, progression-free survival, measures of safety (adverse events) and resource use to 2 years. …”
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  8. 12048

    Successful Treatment of Tumor-Induced Osteomalacia by Multidisciplinary Therapy with Radiation to Intracranial Fibromyxoid Tumor by Mariangela Massaccesi, Francesco Miccichè, Mario Rigante, Gianluigi Petrone, Elisabetta Lepre, Maria Antonietta Gambacorta, Vincenzo Valentini

    Published 2021-01-01
    “…After five years from treatment, the patient is free from local tumor relapse, TIO progression, and radiation-induced side effects. Conclusions. …”
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  9. 12049

    Co-Localized in Amyloid Plaques Cathepsin B as a Source of Peptide Analogs Potential Drug Candidates for Alzheimer’s Disease by Marilena K. Theodoropoulou, Konstantina D. Vraila, Nikos C. Papandreou, Georgia I. Nasi, Vassiliki A. Iconomidou

    Published 2024-12-01
    “…The oligomeric form of A<i>β</i> is acknowledged as the most neurotoxic, propelling the pathological progression of AD. Interestingly, besides A<i>β</i>, other proteins are co-localized within amyloid plaques. …”
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  10. 12050

    பாரதியாரின் பார்வையில் கல்வி / Education in the Viewpoint of Bharathiyar by முனைவர் பா. விக்னேஷ்குமார் / Dr. P. Vignesh Kumar

    Published 2025-01-01
    “…The present era is often characterized as an age of progress that is primarily driven by the advancements in economy and technology. …”
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  11. 12051

    Anchored and epoxied ferrocement strips for improving flexural performance of two-way reinforced concrete slabs by Galal Elsamak, Mohamed Ghalla, Moataz Badawi, Abdullah Albogami, Taher A. Tawfik, Ramy I. Shahin

    Published 2025-07-01
    “…The model highlighted the progression of stresses leading to ID failure and demonstrated how varying reinforcement ratios and anchoring methods influence the structural performance of the strengthened slabs.…”
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  12. 12052

    A network-based systems genetics framework identifies pathobiology and drug repurposing in Parkinson’s disease by Lijun Dou, Zhenxing Xu, Jielin Xu, Chengxi Zang, Chang Su, Andrew A. Pieper, James B. Leverenz, Fei Wang, Xiongwei Zhu, Jeffrey Cummings, Feixiong Cheng

    Published 2025-01-01
    “…However, current treatments only manage symptoms and lack the ability to slow or prevent disease progression. We utilized a systems genetics approach to identify potential risk genes and repurposable drugs for PD. …”
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  13. 12053

    Online education in palliative care - A national exploratory multimethod study by Carina Lundh Hagelin, Christina Melin-Johansson, Jane Österlind, Birgitta Bisholt, Susanna Pusa

    Published 2024-12-01
    “…Abstract Background With an increased number of people living with multiple progressive diseases, online education courses have been created to address the growing need for competence in palliative care. …”
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  14. 12054

    Traffic-related air pollution (TRAP) exposure, lung function, airway inflammation and expiratory microbiota: A randomized crossover study by Rongrong Xu, Yanping Zhang, Tingting Wu, Hao Liu, Jianhao Peng, Zhanshan Wang, Te Ba, Baorong Zhang, Zhigang Li, Yongjie Wei

    Published 2025-01-01
    “…Recently, lung microbiome is proposed to be characterized with development and progression of respiratory diseases. However, the underlying effects of TRAP exposure on lung microbiome are rarely explored. …”
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  15. 12055

    Eyecare practitioner perspectives and attitudes towards myopia and myopia management in the UK by Sophie Coverdale, Lindsay Rountree, Kathryn Webber, Matthew Cufflin, Edward Mallen, Alison Alderson, Neema Ghorbani-Mojarrad

    Published 2024-05-01
    “…Objective Many children with progressive myopia are still prescribed single-vision correction. …”
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  16. 12056

    A national survey of physicians regarding active surveillance for low-risk thyroid cancer in Korea by Min Joo Kim, Jae Hoon Moon, Eun Kyung Lee, Young Shin Song, Kyong Yeun Jung, Ji Ye Lee, Ji-hoon Kim, Woojin Lim, Kyungsik Kim, Sue K. Park, Young Joo Park

    Published 2025-01-01
    “…Although the respondents recognized the benefits of AS, such as avoiding surgery and reducing surgical complications, they expressed concerns about potential risks, including the possibility of patient lawsuits due to disease progression and patient worry and anxiety about the disease. …”
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  17. 12057

    An Effect of Ursodeoxycholic Acid on Inflammation, Steatosis and Liver Fibrosis and Atherogenesis Factors in Patients with Non-Alcoholic Fatty Liver Disease: Results of the USPEH S... by M. V. Mayevskaya, M. Yu. Nadinskaia, V. D. Lunkov, I. Yu. Pirogova, E. V. Chesnokov, Kh. B. Kodzoeva, V. T. Ivashkin

    Published 2020-01-01
    “…Against the background of UDCA administration, there was no progression of liver fibrosis. None of the participants in the observational programme reached a normal body mass by the end of the program; therefore, the attained positive changes should be attributed directly to the effects of UDCA.…”
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  18. 12058

    Learning Automata Based Incremental Learning Method for Deep Neural Networks by Haonan Guo, Shilin Wang, Jianxun Fan, Shenghong Li

    Published 2019-01-01
    “…Deep learning methods have got fantastic performance on lots of large-scale datasets for machine learning tasks, such as visual recognition and neural language processing. Most of the progress on deep learning in recent years lied on supervised learning, for which the whole dataset with respect to a specific task should be well-prepared before training. …”
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  19. 12059

    Gut Microbiota as Emerging Players in the Development of Alcohol-Related Liver Disease by Wei Li, Wenkang Gao, Shengqi Yan, Ling Yang, Qingjing Zhu, Huikuan Chu

    Published 2024-12-01
    “…Recent research highlights the gut microbiota’s significant role in the progression of alcohol-related liver disease. In patients with alcohol-related liver disease, the relative abundance of pathogenic bacteria, including <i>Enterococcus faecalis</i>, increases and is positively correlated with the level of severity exhibited by alcohol-related liver disease. …”
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  20. 12060

    Salivary Metabolomics of Well and Poorly Controlled Type 1 and Type 2 Diabetes by Sompop Bencharit, James Carlson, Warren C. Byrd, Escher L. Howard-Williams, Jackson T. Seagroves, Susan McRitchie, John B. Buse, Susan Sumner

    Published 2022-01-01
    “…The concentrations of endogenous metabolites in saliva can be altered based on the systemic condition of the hosts and may, in theory, serve as a reflection of systemic disease progression. Hemoglobin A1C is used clinically to measure long-term average glycemic control. …”
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