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11921
Hybrid Quality-Based Recommender Systems: A Systematic Literature Review
Published 2025-01-01“…This study aims to assess the progress achieved in the field of hybrid recommender systems to identify frequently used recommender approaches, explore the technical context, highlight gaps in the existing research, and position our future research in relation to the current studies.…”
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11922
Reasons for disengagement in first-episode psychosis – perspectives from service users and their caregivers
Published 2024-11-01“…A total of five categories each with subthemes were identified from the reasons for service user disengagement – individual factors, stigma, progression, treatment factors, and external factors. …”
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11923
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11924
Papillary Carcinoma of Breast: Clinicopathological Characteristics, Management, and Survival
Published 2022-01-01“…HER-2 Neu was positive in 3 patients only, out of which 2 died of progressive disease (one EPC and one IPC). LN metastasis was present in 3 (5%) patients (one in each of 1st three types) and only one died of bone metastasis that was also Her-2Neu positive. …”
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11925
Comorbidity in in patients with relapsing-remitting multiple sclerosis
Published 2024-10-01“…Comorbidity in multiple sclerosis is an urgent problem of modern neurology, since it can influence such factors as the time of diagnosis, the rate of disease progression and the rate of patient disability, the number of exacerbations and the patient’s quality of life. …”
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11926
Extracellular domain of TREM2 possess two distinct ligand recognition sites: Insights from machine-learning guided docking and all-atoms molecular dynamics simulations
Published 2025-01-01“…R47H and R62H in TREM2 may affect the development and progression of AD. Our knowledge-based and machine-learning guided docking and physics-based simulations study unveils deep insights into the endogenous ligand recognition by the positive surface ligand binding site and distant core site pave the way for exploration of other small molecules towards development of novel therapeutics against Alzheimer's disease.…”
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11927
Correlation of Platelet Indices with Severity of Gastroesophageal Varices in Patients of Liver Cirrhosis: A Research Protocol
Published 2025-02-01“…While various parameters have been explored to predict the progression and severity of these varices, platelet indices have not been extensively studied in cirrhosis patients with gastroesophageal varices in India. …”
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11928
One-year Prevalence, Comorbidities, and Cost of Hospitalizations for Alpha-1 Antitrypsin Deficiency among Patients with Chronic Obstructive Pulmonary Disease in the United States
Published 2017-07-01“…Future research should assess other differences between AATD and the general COPD population such as natural history of disease, treatment responsiveness and disease progression.…”
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11929
Weighted Gene Coexpression Network Analysis Identifies TBC1D10C as a New Prognostic Biomarker for Breast Cancer
Published 2022-01-01“…We downloaded raw data from several databases including TCGA and MDACC to identify TME hub genes associated with overall survival (OS) and the progression-free interval (PFI) by WGCNA. Correlations between hub genes and either tumor-infiltrating immune cells or immune checkpoints were conducted by ssGSEA. …”
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11930
Geospatial visualization and seasonal variation of heavy metals in river sediments
Published 2023-04-01“…Industrialization and agricultural developments are progressively causing ecological concerns, which must be addressed. …”
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11931
The Value of Immune-Related Genes Signature in Osteosarcoma Based on Weighted Gene Co-expression Network Analysis
Published 2021-01-01“…This study is aimed at obtaining immune-related genes (IRGs) associated with the progression and prognosis of OS. Method. Expression profiling data and clinical data for OS were downloaded from the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) database. …”
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11932
Efficacy of an Emergency Cervical Cerclage Using Absorbable Monofilament Sutures
Published 2018-01-01“…Among the 23 patients (18 singleton and five twin pregnancies) evaluated, ultrasound-indicated (progressive cervical length shortening) were eight (35%) and physical examination-indicated (fetal membranes that prolapsed into the vagina or dilated cervix) were 15 patients (65%). …”
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11933
Therapeutic Potential of <i>Lappula patula</i> Extracts on Germline Development and DNA Damage Responses in <i>C. elegans</i>
Published 2025-01-01“…Results: Exposure to <i>L. patula</i> extracts resulted in a dose-dependent reduction in worm survival and larval developmental progress, with no significant impact on the male incidence. …”
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11934
Efficacy and safety of new protease inhibitor faldaprevir in treatment of hepatitis C
Published 2013-12-01“…To discuss potentials of application of new NS3/NS4 protease inhibitor faldaprevir at chronic hepatitis C with genotype 1 HCV, including patients without response to previous antiviral therapy, liver cirrhosis, and to estimate its antiviral activity in the range of treatment modes without interferon.Key points. Significant progress was achieved in development of new modes of antiviral treatment of patients with the 1st HCV genotype due to introduction of the third agent possessing direct antiviral action. …”
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11935
Application of Surgical Protocols for the Treatment of Highly Irregular Astigmatism with Topographic Guided Ablation in a Case of Post-LASIK Ectasia
Published 2025-01-01“…Epithelium-off corneal cross-linking was performed at 3.0 mW/cm for 30 minutes.Results: The patient initially presented with a remote history of LASIK and progressive left eye blurring. His uncorrected distance visual acuity (UDVA) was 20/40, with a corrected distance visual acuity (CDVA) of 20/25 with a manifest refraction of − 1.25 +1.75 × 180. …”
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11936
Molecular and serological investigation of hepatitis B virus in patients with acute undifferentiated febrile illness at Tha Song Yang hospital, Tak Province, Thailand
Published 2025-01-01“…Abstract Background Hepatitis B virus (HBV) infection is associated with hepatitis, often progressing to liver cirrhosis or cancer, posing a significant public health challenge, particularly in Thailand. …”
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11937
The potential of stem cell therapy in Multiple Sclerosis treatment: a review
Published 2023-12-01“…Most current clinical trials continue to focus on establishing the safety and efficacy of adipose derived stem cell-based therapeutics, with promising results becoming progressively evident. This review reports stem cell-based therapies as potential therapeutic approaches in the treatment and management of Multiple Sclerosis. …”
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11938
Informing the development of diagnostic criteria for differential diagnosis of alcohol-related cognitive impairment (ARCI) among heavy drinkers: A systematic scoping review.
Published 2023-01-01“…These studies revealed a lack of coordinated research and progress towards the development and standardisation of diagnostic criteria for ARCI. …”
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11939
Impact of Comorbidities on the Severity of Disease & Outcome in Children with COVID 19 at a Tertiary Care Pediatric Hospital, Rawalpindi.
Published 2023-06-01“…It is considered that COVID-19, in those with underlying health conditions or co-morbidities, has an increasingly rapid and severe progression, often leading to death. This study is designed to evaluate the impact of co-morbidities on the severity and outcome of COVID-19 infection in children. …”
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11940
Early referral to nephrological care improves long-term survival and hospitalization after dialysis initiation, independent of optimal dialysis start – a call for harmonization of...
Published 2024-12-01“…Early treatment of kidney disease can slow disease progression and reduce the increased risk of mortality associated with end-stage kidney disease. …”
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