In Vivo Evaluation of the Ameliorating Effects of Small-Volume Resuscitation with Four Different Fluids on Endotoxemia-Induced Kidney Injury by Yan-ling Wang, Jing-hui Chen, Qiong-fang Zhu, Gao-feng Yu, Chen-fang Luo, Gang-jian Luo, Shang-rong Li, Zi-qing Hei

“…LPS injection caused reduced and progressively deteriorated systemic (arterial blood pressure) and renal hemodynamics (renal blood flow and renal vascular resistance index) over time. …”
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THE PGR NETWORKS IN FRANCE: COLLABORATION OF USERS AND THE GENETIC RESOURCE CENTRE ON SMALL GRAIN CEREALS by A. Didier, L. Bardy, E. Boulat, J. Koenig, A. Lapierre, F. Exbrayat, J. Bordes, F. Balfourier

“…All these data obtained from the French small grain cereal Network will be progressively available through the INRA Genetic Resource Website (http://urgi.versailles.inra.fr/siregal/siregal/welcome.do).…”
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CD40 Gene Polymorphisms Associated with Susceptibility and Coronary Artery Lesions of Kawasaki Disease in the Taiwanese Population by Ho-Chang Kuo, Mei-Chyn Chao, Yu-Wen Hsu, Ying-Chi Lin, Ying-Hsien Huang, Hong-Ren Yu, Ming-Feng Hou, Chi-Di Liang, Kuender D. Yang, Wei-Chiao Chang, Chih-Lu Wang

“…Our previous studies showed expression of CD40 ligand on CD4+ T cells correlated to the coronary artery lesion (CAL) and disease progress in KD. Other studies from Japan suggested the role of CD40L in the pathogenesis of CAL, and this might help explain the excessive number of males affected with KD but cannot be reproduced by Taiwanese population. …”
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Metabolomic Profiling Reveals Potential Biomarkers and Prominent Features in HIV/AIDS Patients Co-Infected with SARS-CoV-2 by Xuan Yan, Xinyu Zhang, Wei Song, Tangkai Qi, Zhenyan Wang, Yang Tang, Jianjun Sun, Shuibao Xu, Junyang Yang, Jiangrong Wang, Jun Chen, Renfang Zhang, Li Liu, Yinzhong Shen

“…The underlying mechanisms and diagnostic biomarkers for the progress of COVID-19 in HIV patients have not been fully elucidated. …”
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Paraneoplastic Neurological Syndromes: Severe Neurological Symptoms Resulting from Relatively Benign or Occult Tumours—Two Case Reports by M. Ghadiri-Sani, Mueez Waqar, Dave Smith, Mark Doran

“…A 64-year-old female was admitted with acute leg weakness, which progressed to quadriplegia and was eventually fatal over the ensuing months. …”
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Vascular involvement in idiopathic pulmonary fibrosis by Michele Mondoni, Rocco Rinaldo, Christopher J. Ryerson, Cristina Albrici, Andrea Baccelli, Claudio Tirelli, Francesca Marchetti, Jacopo Cefalo, Giulia Nalesso, Giulia Ferranti, Fausta Alfano, Giovanni Sotgiu, Marco Guazzi, Stefano Centanni

“…Background Idiopathic pulmonary fibrosis (IPF) is a chronic, fibrosing and progressive interstitial lung disease of unknown aetiology with a pathogenesis still partly unknown. …”
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Recent advances in bacterial outer membrane vesicles: Effects on the immune system, mechanisms and their usage for tumor treatment by Shuo Xiang, Qiufang Yao, Arshad Khan, Dong Wang

“…This article provides an overview of the structural composition and immune mechanisms of OMVs, details various OMVs modification strategies, and reviews the progress in using OMVs for tumor treatment and their anti-tumor mechanisms. …”
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STAT1, IGF1, RAC1, and MDM2 Are Associated with Recurrence of Giant Cell Tumor of Bone by Shuxin Chen, Zepeng Du, Bingli Wu, Huiyang Shen, Chunpeng Liu, Xueli Qiu, Yufeng Zhang, Liyan Xu, Enmin Li, Zhigang Zhong

“…Functional enrichment analysis showed that this network involves many important biological progress mediated by these four genes, including immune response. …”
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Experimental and Computational Study of Trapped Vortex Combustor Sector Rig with High-Speed Diffuser Flow by R. C. Hendricks, D. T. Shouse, W. M. Roquemore, D. L. Burrus, B. S. Duncan, R. C. Ryder, A. Brankovic, N.-S. Liu, J. R. Gallagher, J. A. Hendricks

“…Further testing over a wider range of fuel-air ratios, fuel flow splits, and pressure ratios is in progress to explore the TVC performance. In addition, alternate configurations for the upstream pressure feed, including bi-pass diffusion schemes, as well as variations on the fuel injection patterns, are currently in test and evaluation phases.…”
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Intraoperative Conversion to ALPPS in a Case of Intrahepatic Cholangiocarcinoma by F. Oldhafer, K. I. Ringe, K. Timrott, M. Kleine, W. Ramackers, S. Cammann, M. D. Jäger, J. Klempnauer, H. Bektas, F. W. R. Vondran

“…In contrast to the preoperative CT-scan, the known lesion showed further progression in a macroscopically steatotic liver. Therefore, the decision was made to perform an ALPPS-procedure to avoid an insufficient future liver remnant (FLR). …”
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ACOX1 activates autophagy via the ROS/mTOR pathway to suppress proliferation and migration of colorectal cancer by Bo Shi, Junjie Chen, Haoran Guo, Xinyu Shi, Qingliang Tai, Guoliang Chen, Huihui Yao, Xiuwei Mi, Runze Zhong, Yang Lu, Yiyuan Zhao, Liang Sun, Diyuan Zhou, Yizhou Yao, Songbing He

“…Abstract Acyl-CoA oxidase 1 (ACOX1), a member of the acyl-coenzyme A oxidase family, is considered a crucial regulator whose dysregulation is implicated in the occurrence and progression of various cancers. This study aims to elucidate the impact of ACOX1 in CRC, shedding light on its potential as a therapeutic target. …”
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Levamisole/Cocaine Induced Systemic Vasculitis and Immune Complex Glomerulonephritis by Lohit Garg, Sagar Gupta, Abhishek Swami, Ping Zhang

“…A 40-year-old Caucasian male with no past medical history presented with 3-week history of fatigue, skin rash, joint pains, painful oral lesions, oliguria, hematuria, worsening dyspnea on exertion, and progressive lower extremity edema. He had a history of regular tobacco and cocaine use. …”
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Disease management teams in oncology: State of the art and the experience of a scientific institute of hospitalization and treatment (IRCCS) in Rome, Italy by Marialuisa Appetecchia, Carlotta Amantea, Marco Canfora, Fabrizio Petrone, Gennaro Ciliberto, Ermete Gallo, Laura Figorilli

“…Conclusion: The results of this study have highlighted that, despite the diversity of the different DMTs created for different oncological pathologies, DMTs guarantee a patient-centered approach and the creation of shared databases, which facilitates the evaluation of progress and the identification of areas for improvement. …”
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Spatiotemporal heterogeneity management: Optimizing the critical role of ecosystem services in achieving Sustainable Development Goals by Lingli Zuo, Guohua Liu, Junyan Zhao, Jiajia Li, Shuyuan Zheng, Xukun Su

“…Western Sichuan demonstrated stronger performance in environment-related SDGs in the Sichuan Province, while the Sichuan Basin showed better progress in socio-economic-related SDGs; (2) habitat quality, carbon sequestration, air pollution removal, and soil retention significantly influenced the development of 9 SDGs; (3) supporting, regulating, and provisioning service bundles have persistent and stable spatiotemporal heterogeneity effects on SDG1, SDG8, SDG11, SDG13, and SDG15. …”
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Fetal Growth Restriction Prediction: How to Move beyond by Debora F. B. Leite, Jose G. Cecatti

“…Apart from only meliorating perinatal outcomes, we hypothesize SGA screening is a key for socioeconomic progress.…”
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Wilson – Konovalov Disease: Clinical Cases with Different Manifestations and Outcomes by O. V. Samodova, G. P. Smirnova, E. A. Krieger

“…In 2 weeks, the patient developed symptoms of acute liver failure, progressive hemorrhagic syndrome, acute hepatic encephalopathy. …”
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An esophageal stent integrated with wireless battery-free movable photodynamic-therapy unit for targeted tumor treatment by Qian Han, Pingjin Zou, Xianhao Wei, Junyang Chen, Xiaojiao Li, Li Quan, Ranlin Wang, Lili Xing, Xinyu Xue, Yi Zhou, Meihua Chen

“…The system can wirelessly and in real-time control the PDT light source's position via external ultrasound, offering a novel approach for treating esophageal cancer patients according to the need of tumor's progression.…”
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New Players for Advanced Prostate Cancer and the Rationalisation of Insulin-Sensitising Medication by Jennifer H. Gunter, Phoebe L. Sarkar, Amy A. Lubik, Colleen C. Nelson

“…However, the initial therapeutic response from ADT eventually progresses to castrate resistant prostate cancer (CRPC) which is currently incurable. …”
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Clinical significance of hyperuricaemia in biopsy-proven diabetic kidney disease ━ a single-centre retrospective study by Jin Yu, Jin Yu, Xiao Tu, Xiao Tu, Kunyue Xu, Xuanli Tang, Xuanli Tang, Yufan Wu, Xue Jiang, Xue Jiang

“…However, the mechanism of hyperuricaemia causing the progression of DKD remain unclear.MethodsThis is a single-centre retrospective study. 155 biopsy-proven DKD patients were grouped into hyperuricaemia and non-hyperuricaemia groups. …”
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The Association of TNF-Alpha Inhibitors and Development of IgA Nephropathy in Patients with Rheumatoid Arthritis and Diabetes by Vedran Premužić, Ivan Padjen, Mislav Cerovec, Marijana Ćorić, Bojan Jelaković, Branimir Anić

“…IgA nephropathy (IgAN) is a rather uncommon complication of TNF-alpha inhibition with a range of findings such as asymptomatic microscopic/macroscopic hematuria or different degrees of proteinuria and could progress to end-stage renal disease. We are reporting three patients with longstanding rheumatoid arthritis (RA), which developed IgAN while receiving TNF-alpha inhibitors. …”
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