Transcriptional engineering for value enhancement of oilseed crops: a forward perspective by Charli Kaushal, Mahak Sachdev, Mansi Parekh, Harini Gowrishankar, Mukesh Jain, Subramanian Sankaranarayanan, Bhuvan Pathak

“…This review explores the application of genome editing in oilseed improvement, covering recent progress, challenges, and future potential to boost yield and oil content. …”
Get full text

Clinical profile and risk factors for respiratory failure in children with Mycoplasma pneumoniae infection by Yanfei Wang, Limin Huang, Junjie Qian, Kelei Deng, Zihao Yang, Zhenjie Chen, Wei Li, Linhua Tan

“…Among the hospitalized MPP cases, 15.8% progressed to respiratory failure. Statistical analysis identified D-dimer level as a significant risk factor for respiratory failure in children with MPP. …”
Get full text

Development and functional validation of a disulfidoptosis-related gene prognostic model for lung adenocarcinoma based on bioinformatics and experimental validation by Tao Shen, Tao Shen, Zhuming Lu, Sisi Yang, Dongxi Zhang, Yongwen Ke, Zhuowen Chen, Jinqiang Wu, Jinqiang Wu, Weidong Wu

“…BackgroundDisulfidoptosis is increasingly linked to cancer progression, yet its immunological impacts and prognostic value in lung adenocarcinoma (LUAD) remain poorly understood. …”
Get full text

Conservation Voltage Reduction in Distribution Networks: A Comprehensive Review by Ibrahim Alzubi, Saher Albatran, Issam A. Smadi, Salman Harasis

“…This paper bridges the gap between theory and practice by providing a comprehensive and systematic review of CVR research progress from various aspects, including the effects of CVR on the operation and efficiency of both individual loads, such as residential appliances, and composite commercial and industrial loads. …”
Get full text

Sparse Gene Coexpression Network Analysis Reveals EIF3J-AS1 as a Prognostic Marker for Breast Cancer by Xin Chen, Zuyuan Yang, Chao Yang, Kan Xie, Weijun Sun, Shengli Xie

“…Accumulating evidence indicates that long noncoding RNAs (lncRNAs) play important roles in cancer progression, with diagnostic and prognostic potential. …”
Get full text

Dual anti-CTLA-4 and anti-PD-1 blockade in metastatic basal cell carcinoma by Sandip P. Patel, Eleanor Cano-Linson, Young Kwang Chae, Shiruyeh Schokrpur, Christopher D. Lao, Benjamin C. Powers, Adrienne I. Victor, Adedayo A. Onitilo, Sarah Shin, Naoko Takebe, Sara Threlkel, Christine M. McLeod, Helen X. Chen, Elad Sharon, Megan Othus, Christopher W. Ryan, Charles D. Blanke, Razelle Kurzrock

“…Overall survival (OS), progression-free survival (PFS), and toxicity were secondary endpoints. …”
Get full text

The Relationship between School Connectedness and Academic Engagement: Mediating Role of Mindfulness by Rouhollah Aghasaleh, Saba Rasouli Amlashi, S. Abdolvahab Samavi

“…Another fundamental concept in the PP literature is school connectedness, which underscores the belief students hold regarding the care shown by adults and peers in the educational environment towards their academic progress and personal welfare. Additionally, mindfulness, a pivotal term in the field of PP, offers noteworthy advantages such as enhancing working memory and reducing stress levels, consequently fostering academic involvement. …”
Get full text

CAV1 promotes epithelial-to-mesenchymal transition (EMT) and chronic renal allograft interstitial fibrosis by activating the ferroptosis pathway by Qianguang Han, Bin Ni, Wei Bao, Junqi Zhang, Ming Zheng, Jinxu Miu, Zijie Wang, Jingwen Yuan, Jun Tao, Zhijian Han, Min Gu, Xiaobing Ju, Ruoyun Tan

“…However, the mechanism by which ferroptosis contributes to the onset and progression of CAD remains unclear.MethodsThis study analyzed transcriptome data from renal transplant biopsy samples in the Gene Expression Omnibus (GEO), through clinical samples, animal models, and cell experiments, this study investigated the mechanism by which Caveolin-1 (CAV1) promotes CAD through the regulation of the ferroptosis pathway.ResultsThe elevated levels of CAV1 were found to positively correlate with CAD incidence. …”
Get full text

Audiological alterations in resistance to thyroid hormone syndrome: emphasizing lifelong assessment by Alexandre Machado Silva de Oliveira, Viviane Motti, Jessica Casemiro, Pedro Resende Rende, Caio Leônidas Oliveira de Andrade, Luciene da Cruz Fernande, Helton Estrela Ramos

“…These findings underscore the importance of lifelong monitoring, particularly to assess age-related progression of hearing impairment.…”
Get full text

Inheriting Feng Yunhua's Traditional Chinese Medicine nursing thought and application in the Traditional Chinese Medicine breast nursing clinic (冯运华中医护理传承思想在中医乳腺护理门诊的应用思考)... by LIU Jing (刘静), ZHANG Furong (张芙蓉), ZHANG Jing (张敬), ZHANG Xuejian (张雪键), ZHAO Danfeng (赵丹凤), TANG Ling (唐玲)

“…According to the 14th Five-Year Plan for the Development of Traditional Chinese Medicine Nursing in Beijing, the aim of establishment of Feng Yunhua Traditional Chinese Medicine nursing Inheritance Workstation is to improve the development of Traditional Chinese Medicine breast nursing clinic in perspectives of clinical treatment, technology progress, clinical research and education. (“冯运华中医护理传承工作站”的建立充分发挥中医护理传承导师冯运华“立足中医经典理论核心, 在实践中推动中医护理从经验型向科学型发展, 以切实提高中医护理临床能力为最终目的”的思想内涵, 深度落实《北京市“十四五”中医发展规划》, 促进中医乳腺护理门诊从临床治疗、技术发展与科研教学等多方面的发展。)…”
Get full text

Co-infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and human coronavirus HKU1 (HCoV-HKU1) by Laszlo Madaras, Radean Anvari, Claudia Schuchardt-Peet, Abhinav Hoskote, Rahul Kashyap

“…Discussion: COVID-19 patients co-infected with other human coronaviruses should be monitored for disease progression and superimposed bacterial infections. Providers should be cautious with the use of remdesivir in cases of co-infection and in severely ill COVID-19 patients who have a history of atrial fibrillation.…”
Get full text

Sistrunk Procedure on Malignant Thyroglossal Duct Cyst by Diani Kartini, Sonar S. Panigoro, Agnes S. Harahap

“…A thyroglossal duct cyst is a lesion that occurs as a result from failure of the thyroglossal duct to obliterate during fetal development. Malignant progression is a rare event that might occur in less than 1% of all cases. …”
Get full text

Application of quantitative histomorphometric features in computational pathology by Yujie Shi, Bo Hu, Mingyan Xu, Yunhan Yao, Shuaiqiang Gao, Xiang Xia, Xikai Deng, Jianfeng Liu, Jia Gu, Shifu Chen

“…The conclusion is that, with the ongoing progress in QH feature representation and segmentation technology, methods based on QH features will leverage their advantages—such as explainability, reduced reliance on large training datasets, and lower computational resource requirements—to play a more significant role in some clinical tasks. …”
Get full text

Qualitative and Quantitative Assessment of the Regenerate Bone Formed During Intramedullary Limb Lengthening Using a Goat (Caprine) Tibia Model: A Pilot Study by Anirejuoritse Bafor, Aidan Isler, Kell Sprangel, Sara McBride-Gagyi, Christopher A. Iobst

“…Results: Regenerate bone appeared as early as the 2nd–4th week of distraction and progressed from the periphery to the center as well as from the bone ends toward the center of the regenerate, delineating a distinct fibrous interzone and a previously undescribed “inner zone.” …”
Get full text

Responsive afatinib treatment in high-grade salivary gland ductal carcinoma and NSCLC with uncommon EGFR mutations: Treatment outcomes by Sivakamavalli Jeyachandran

“…Clinical trials confirm significant tumor responses and improved progression-free survival with afatinib treatment. Similarly, in NSCLC, uncommon EGFR mutations historically resistant to conventional inhibitors respond favorably to afatinib, as evidenced by clinical trials and real-world data. …”
Get full text

The Evolution of Dendritic Cell Immunotherapy against HIV-1 Infection: Improvements and Outlook by Hager Mohamed, Vandana Miller, Stephen R. Jennings, Brian Wigdahl, Fred C. Krebs

“…During the course of HIV-1 infection, a successful adaptive (cytotoxic CD8+ T-cell) response is necessary for preventing the progression and spread of infection in a variety of cells. …”
Get full text

Retinal Ganglion Cell Atrophy in Homonymous Hemianopia due to Acquired Occipital Lesions Observed Using Cirrus High-Definition-OCT by Tsutomu Yamashita, Atsushi Miki, Katsutoshi Goto, Syunsuke Araki, Go Takizawa, Yoshiaki Ieki, Junichi Kiryu, Akio Tabuchi, Yasuyuki Iguchi, Kazumi Kimura, Yoshiki Yagita

“…Also, it is suggested that the retinal changes observed are progressive.…”
Get full text

Proteomic Analysis of MCF-7 Breast Cancer Cell Line Exposed To Leptin by A. Valle, J. Sastre-Serra, C. Pol, A. M. Miró, J. Oliver, P. Roca

“…Circulating leptin levels are increased in obese and it has been suggested to play an important role in mammary tumor formation and progression. To contribute to the understanding of the molecular mechanisms underlying leptin action in breast cancer, our aim was to identify proteins regulated by leptin in MCF-7 human breast cancer cells. …”
Get full text

Effect of Enzymatic Hydrolysis Time on the Structure and Emulsifying Properties of Soybean Meal Hydrolysate and Preparation and Characterization of Highly Stable Emulsions Stabiliz... by LIU Jingbo, LI Zihao, WEN Hedi, LÜ Siwen, YU Yiding, ZHANG Ting

“…The results showed that as enzymatic hydrolysis progressed, the degree of hydrolysis (DH) gradually increased, and the emulsifying properties of soybean meal hydrolysate first increased and then decreased, reaching the maximum value at 2 h. …”
Get full text

Exploring South Africa’s Foreign Policy Objectives in the Decolonisation of the Intergovernmental Organisations: The Case of the United Nations Security Council by Thoriso Ntlailane, Costa Hofisi

“…The findings show that the process of decolonisation within the UNSC is occurring at a very slow pace, although significant progress has been made within the African Union regarding the decolonisation agenda. …”
Get full text