Preoperative Low-Density Lipoprotein Apheresis for Preventing Recurrence of Focal Segmental Glomerulosclerosis after Kidney Transplantation by Akihito Sannomiya, Toru Murakami, Ichiro Koyama, Kosaku Nitta, Ichiro Nakajima, Shohei Fuchinoue

“…Focal segmental glomerulosclerosis (FSGS) often develops rapidly and frequently progresses to renal failure, while the recurrence rate after kidney transplantation is 20–50%. …”
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Social innovations to increase health coverage: evidence from a crowdsourcing contest in Ghana by Joseph D Tucker, Phyllis Dako-Gyeke, Phyllis Awor, Emmanuel Asampong, Kwabena Opoku-Mensah, Philip Teg-Nefaah Tabong

“…Objectives Despite progress made to expand access to health service in Ghana, inequities still exist. …”
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The Association of Pseudohypoparathyroidism Type Ia with Chiari Malformation Type I: A Coincidence or a Common Link? by Paria Kashani, Madan Roy, Linda Gillis, Olufemi Ajani, M. Constantine Samaan

“…A 19-month-old boy was referred for progressive weight gain. His past medical history included congenital hypothyroidism and developmental delay. …”
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Extraocular Surgical Approach for Placement of Subretinal Implants in Blind Patients: Lessons from Cochlear-Implants by Assen Koitschev, Katarina Stingl, Karl Ulrich Bartz-Schmidt, Angelika Braun, Florian Gekeler, Udo Greppmaier, Helmut Sachs, Tobias Peters, Barbara Wilhelm, Eberhart Zrenner, Dorothea Besch

“…In hereditary retinal diseases photoreceptors progressively degenerate, often causing blindness without therapy being available. …”
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A Combined Computational and Experimental Study on Nanoparticle Transport and Partitioning in the Human Trachea and Upper Bronchial Airways by Jiawei Ma, Wei-Chung Su, Yi Chen, Yidan Shang, Jingliang Dong, Jiyuan Tu, Lin Tian

“…With rapid advances in medical imaging and computational capacities, sophisticated human tracheobronchial trees that include the 6th, 7th or 15th generation have been increasingly described in the literature. However, continued progress in anatomical reconstruction and mathematical idealized modeling, the two most frequently employed approaches to airway modeling, requires a detailed fundamental analysis on the morphology-induced sensitivity of particle-flow partitioning, and particle deposition in the airways. …”
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Combining genomics and epidemiology to investigate a zoonotic outbreak of rabies in Romblon Province, Philippines by Mirava Yuson, Criselda T. Bautista, Eleanor M. Rees, Carlijn Bogaardt, Van Denn D. Cruz, Rowan Durrant, Anna Formstone, Daria L. Manalo, Duane R. Manzanilla, Mikolaj Kundergorski, Leilanie Nacion, Hannaniah Aloyon, Jude Karlo Bolivar, Jeromir Bondoc, Christina Cobbold, Efraim Panganiban, Shynie Vee. M. Telmo, Jobin Maestro, Mary Elizabeth G. Miranda, Nai Rui Chng, Kirstyn Brunker, Katie Hampson

“…We conclude that strengthened surveillance making use of new tools such as IBCM, WGS, and rapid diagnostic tests can support One Health in action and progress towards the ‘Zero by 30’ goal.…”
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Genomic characterization of Escherichia coli with a polyketide synthase (pks) island isolated from ulcerative colitis patients by Chao Lv, Mohd Abdullah, Chun-Li Su, Weiye Chen, Nan Zhou, Zile Cheng, Yiwen Chen, Min Li, Kenneth W. Simpson, Ahmed Elsaadi, Yongzhang Zhu, Steven M. Lipkin, Yung-Fu Chang

“…Abstract The E. coli strains harboring the polyketide synthase (pks) island encode the genotoxin colibactin, a secondary metabolite reported to have severe implications for human health and for the progression of colorectal cancer. The present study involves whole-genome-wide comparison and phylogenetic analysis of pks harboring E. coli isolates to gain insight into the distribution and evolution of these organisms. …”
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Catastrophic lava flow levee failure: precursors, processes, and implications by Elisabeth Gallant, Hannah R. Dietterich, Matthew R. Patrick, David Hyman, Brett B. Carr, John Lyons, Elinor S. Meredith

“…We use field monitoring, infrasound, time lapse imagery, and lidar data collected during the 2018 lower East Rift Zone eruption of Kīlauea (Hawai‘i) to track the origins, progression, and implications of a flow branching event caused by catastrophic levee failure. …”
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Targeting Caveolin‐1 in Multiple Myeloma Cells Enhances Chemotherapy and Natural Killer Cell‐Mediated Immunotherapy by Dewen Zhan, Zhimin Du, Shang Zhang, Juanru Huang, Jian Zhang, Hui Zhang, Zhongrui Liu, Eline Menu, Jinheng Wang

“…Here, it is found that caveolin‐1 (CAV1), a primary component of membrane lipid rafts and caveolae, is highly expressed in MM cells and is associated with MM progression and drug resistance. CAV1 knockdown decreases MM cell adhesion to stromal cells and attenuates cell adhesion‐mediated drug resistance to bortezomib. …”
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Major trends in human capital development in modern information technology market by A. R. Babayants, A. V. Zakharov

“…Digitalization as part of the trends of accelerating scientific and technological progress and transition to Industry 4.0 determines the need to pay increased attention to creating conditions for human capital development. …”
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A Triple Obstetric Challenge of Thoracopagus-Type Conjoined Twins, Eclampsia, and Obstructed Labor: A Case Report from Sub-Saharan Africa by Mariatu Binta Leigh, Valerie John-Cole, Mike Kamara, Alimamy Philip Koroma, Michael Momoh Koroma, Edward Ejiro Emuveyan, Peter Bramlage, Ivo Buschmann

“…Application of Hydralazine 5 mg (i.v.) under close blood pressure monitoring was performed. Under spontaneous progression of labor, one head of the yet unknown conjoined twin was born. …”
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Anti-Thyroid Peroxidase Antibodies and Male Gender Are Associated with Diabetes Occurrence in Patients with Beta-Thalassemia Major by Giovanni M. Pes, Francesco Tolu, Maria P. Dore

“…In patients with β-T major a progressive damage of insulin-producing cells due to secondary hemosiderosis appears to be the most reasonable mechanism associated with glucose metabolism disorders. …”
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Education as a Fundamental Element in Ensuring the National Security of the State by Vasilii A. Dadalko, Aleksandr G. Kostanyants, Gleb A. Neustroev

“…It forms qualified personnel capable of ensuring technological progress, economic stability and defense against external threats. …”
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Fever, Myositis, and Paralysis: Is This Inflammatory Myopathy or Neuroinvasive Disease? by Aneeta R. Kiran, Richard A. Lau, Kim M. Wu, Andrew L. Wong, Philip J. Clements, Emil R. Heinze

“…The patient’s condition declined despite aggressive supportive care and hydration, and on hospital day #6 he developed severe altered mental status and progressed to complete right arm paralysis and 2/5 muscle strength in bilateral legs. …”
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Hepatoma cell-derived exosomal SNORD52 mediates M2 macrophage polarization by activating the JAK2/STAT6 pathway by Yaqiong Zhang, Bo Li, Wanhong Gu, Linna Fan, Xiaofan Wang, Meifen Xu, Minqi Zhu, Chong Jin

“…However, the potential role of exosomal SNORD52 in macrophage polarization during HCC progression remains poorly understood. Methods Exosomes were isolated from hepatoma cells. …”
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Post-Translational Modifications of Proteins Orchestrate All Hallmarks of Cancer by Pathea Shawnae Bruno, Aneeta Arshad, Maria-Raluca Gogu, Natalie Waterman, Rylie Flack, Kimberly Dunn, Costel C. Darie, Anca-Narcisa Neagu

“…PTMs associated with cancer can be exploited to better understand the underlying molecular mechanisms of this heterogeneous and chameleonic disease, find new biomarkers of cancer progression and prognosis, personalize oncotherapies, and discover new targets for drug development.…”
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Vitamin Status as a Determinant of Serum Homocysteine Concentration in Type 2 Diabetic Retinopathy by Pandelis Fotiou, Athanasios Raptis, George Apergis, George Dimitriadis, Ioannis Vergados, Panagiotis Theodossiadis

“…Our findings suggest that hyperhomocysteinemia is an independent risk factor for the development and progression of diabetic retinopathy. Decreased serum levels of folic acid and vitamin B12, through raising serum homocysteine concentrations, may also affect the diabetic retinopathy risk.…”
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A Randomized Controlled Trial in Obese Adults with Polycystic Ovarian Syndrome: Examining the Impact of Short-term Integrated Naturopathy and Yoga Interventions on Testosterone, Ox... by Balakrishna Shetty, Geetha Balakrishna Shetty, H. L. Nanjeshgowda, Prashanth Shetty

“…Conclusion: The results indicate that short-term integrated yoga and naturopathy interventions are effective in modifying the disease progression of PCOS through endocrinological and metabolic balance.…”
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Differential Immunogenicity and Protective Efficacy Elicited by MTO- and DMT-Adjuvanted CMFO Subunit Vaccines against Mycobacterium tuberculosis Infection by Nadeem Ullah, Ling Hao, Yaqi Wu, Yandi Zhang, Qing Lei, Jo-Lewis Banga Ndzouboukou, Xiaosong Lin, Xionglin Fan

“…In this study, we compared the immunogenicity and protective efficacy of CMFO subunit vaccines against primary progressive TB in two different adjuvant systems: the MTO oil-in-water (O/W) emulsion composed of monophosphoryl lipid A (MPL), trehalose-6,60-dibehenate (TDB), and oil in water emulsion MF59 and the DMT liposome containing dimethyldioctadecylammonium bromide (DDA), monophosphoryl lipid A (MPL), and trehalose-6,60-dibehenate (TDB). …”
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Effect of Bodyweight Squat Exercise With Blood Flow Restriction on Sprint and Jump Performance in Collegiate Soccer Players by Okan Kamiş, Hadi Nobarı, Christopher Macdonald, Robert Blaisdell, Muhammet Kurt

“…Limb occlusion pressure (LOP) was measured in a supine position after 10 min of passive rest by the automated device. Progressive overload was achieved by increasing LOP % weekly. …”
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