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11621
Immunohistochemical Expression of Dual-Specificity Protein Phosphatase 4 in Patients with Colorectal Adenocarcinoma
Published 2015-01-01“…DUSP4 protein is frequently upregulated in colorectal adenocarcinoma and may play an important role in carcinogenesis and cancer progression and may be a marker of adverse prognosis.…”
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11622
The Role of Oral Biomarkers in the Assessment of Noncommunicable Diseases
Published 2024-12-01“…Among others, elevated levels of salivary glucose and inflammatory cytokines correlate with diabetes progression, while vascular endothelial growth factor (VEGF) and salivary C-reactive protein might be applicable as indicators for periodontal disease and cardiovascular risk. …”
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11623
Post-Autologous (ASCT) Stem Cell Transplant Therapy in Multiple Myeloma
Published 2014-01-01“…Autologous stem cell transplant (ASCT) is the standard of care in transplant-eligible multiple myeloma patients and is associated with significant improvement in progression-free survival (PFS), complete remission rates (CR), and overall survival (OS). …”
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11624
PARP inhibition-associated heterochromatin confers increased DNA replication stress and vulnerability to ATR inhibition in SMARCA4-deficient cells
Published 2025-01-01“…PARP inhibition triggers chromatin changes, namely elevated histone H3 at lysine 9 di-methylation (H3K9me2), a hallmark of facultative heterochromatin, increasing dependence on ATR activity for replication fork progression and cell survival. Interestingly, SMARCA4 deficient cells, intrinsically vulnerable to replication stress, exhibited exacerbated DNA damage upon combined ATRi and PARPi treatment in a Mre11- and Mus81-mediated manner. …”
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11625
Optimization of Flow Shop Scheduling in Precast Concrete Component Production via Mixed-Integer Linear Programming
Published 2021-01-01“…The production cost of PC components significantly affects the development of the precast industry and the progress of prefabrication projects. To reduce the production cost, both the delivery delay time and component storage time must be reduced. …”
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11626
Expression of Cyclin D1 in Oral Squamous Cell Carcinoma
Published 2021-12-01“…Its deregulation or overexpression may cause disruption in the normal cell cycle control and lead to cancer progression. In this study, we aimed to study the expression of cyclin D1 in oral squamous cell carcinoma (OSCC) and find its association with the different grades of oral tumors, if any. …”
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11627
Severe Wound Infection with Photobacterium damselae ssp. damselae and Vibrio harveyi, following a Laceration Injury in Marine Environment: A Case Report and Review of the Literatur...
Published 2013-01-01“…A majority of those cases presenting as severe wound infection are even fatal following progression into necrotizing fasciitis. Management with daily wound dressing and antibiotic therapy (ofloxacin empirically, followed by doxycycline after availability of microbiology) led in the reported case to a favorable outcome, which seems to be, however, the exception based on a review of the available literature.…”
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11628
Significance of Glutathione Peroxidase 1 and Caudal-Related Homeodomain Transcription Factor in Human Gastric Adenocarcinoma
Published 2013-01-01“…The expression of GPX1 and CDX2 may play a role in the carcinogenesis, differentiation, and progression of GAC, and CDX2 may be an independent prognostic factor.…”
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11629
Role of Inflammation Markers and Osteopontin in the Prediction of Fetal Stress
Published 2024-07-01“…The study included 30 term pregnancies who underwent cesarean section for fetal distress and 30 pregnant women who underwent cesarean section for other indications (prior uterine surgery, head-pelvis incompatibility, large baby, non-progressing plot) as a control group. The levels of OPN and other inflammatory markers (leukocytes, sedimentation, CRP) in the maternal venous blood of 60 pregnant women were compared, and whether there was a significant association between the groups was investigated. …”
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11630
HDSA-Net: Haze Density and Semantic Awareness Network for Hyperspectral Image Dehazing
Published 2025-01-01“…In particular, SEB adapts SAM for the special HSI data and SPBs enable the network to progressively recover semantic information via channel-level coarse guidance and pixel-level fine guidance. …”
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11631
Acute Low-Dose Hydralazine-Induced Lupus Pneumonitis
Published 2017-01-01“…Three months later, after multiple unsuccessful courses of prednisone and antibiotics for presumed pneumonia and asthma exacerbations, her respiratory symptoms progressed in severity and she developed resting hypoxia. …”
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11632
Strong immune responses and robust protection following a novel protein in adjuvant tuberculosis vaccine candidate
Published 2025-01-01“…These findings support the progression of this vaccine candidate to the next stages of development.…”
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11633
Limiting the development of anti-cancer drug resistance in a spatial model of micrometastases
Published 2016-07-01“…Given the responsiveness of very different theoretical cell lines to these few fractionated-dose protocols, these may represent more effective ways to schedule chemotherapy with the goal of limiting metastatic tumor progression.…”
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11634
Cervical Bone Graft Candida albicans Osteomyelitis: Management Strategies for an Uncommon Infection
Published 2014-01-01“…The diagnosis requires a high degree of suspicion. The insidious progression of infection and the nonspecificity of laboratory and radiologic findings may contribute to a delay in diagnosis. …”
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11635
Photobiomodulation in ocular therapy: current status and future perspectives
Published 2025-02-01“…Hence the future of photobiomodulation holds significant potential in medicine especially in ocular diseases characterized by progress in research, technology, and clinical trials.…”
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11636
Structural characteristics, functions, and counteracting strategies of biofilms in Staphylococcus aureus
Published 2025-01-01“…By mapping future research directions, this review aims to refine anti-biofilm strategies to control infection progression and effectively mitigate recurrence.…”
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11637
A Comparative Study of the Psychology of Color in the Contemporary Poetry of Iranian and Afghanistanian Women Based on Max Luscher's Theory; A Case Study of the Poems of Forough Fa...
Published 2024-09-01“…The examination of the poetry notebooks of these two poets reveals that the use of calm and optimistic colors progressively replaces the use of dark colors. This demonstrates their aspiration and optimism for a more fulfilling existence, as well as their interest in implementing appropriate modifications to the image that evokes their emotions.…”
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11638
Falls Reduction and Exercise Training in an Assisted Living Population
Published 2015-01-01“…In this cross-sectional study, this progressive resistance exercise training program into an assisted living population was associated with a decrease in the number of fall incidents.…”
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11639
Long Term Survival and Continued Complete Response of Vemurafenib in a Metastatic Melanoma Patient with BRAF V600K Mutation
Published 2016-01-01“…BRAF kinase inhibitors such as Vemurafenib have shown improvement in overall survival, progression-free survival, and response rates in patients with metastatic melanoma with BRAF V600K mutation. …”
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11640
Evaluating the Factors Affecting COVID-19 Patients’ Mortality in Arak in 2020
Published 2022-01-01“…From June to October 2020, 98 expired and 196 recovered patients were studied for risk factors, underlying diseases, and laboratory findings that could lead to disease progression and mortality. Results. There was a significant relationship in terms of blood pressure, age, oxygen saturation, tachycardia, tachypnea, the interval between the onset of symptoms and hospitalization, diabetes mellitus, lung disease, cardiovascular disease, history of opium abuse, C-reactive protein, white blood cell, lymphocytes, hemoglobin, creatinine elevation, elevated liver enzyme, creatine phosphokinase, lactate dehydrogenase, ferritin, D-dimer, troponin, prothrombin time, international normalized ratio, intensive care unit admission days, arrhythmia, sepsis, acute respiratory distress syndrome, acute kidney injury (AKI), and the type of antiviral and antibiotic therapy between the two groups of patients. …”
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