Systems Biology Profiling of AMD on the Basis of Gene Expression by Mones S. Abu-Asab, Jose Salazar, Jingsheng Tuo, Chi-Chao Chan

“…Genetic pathways underlying the initiation and progression of age-related macular degeneration (AMD) have not been yet sufficiently revealed, and the correlations of AMD’s genotypes, phenotypes, and disease spectrum are still awaiting resolution. …”
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Dissolution mechanism of Al2O3 in refining slags containing Ce2O3 by Wang L.J., Wang Q., Li J.M., Chou K.C.

“…The mechanism of dissolution of Al2O3 in the Ce2O3 containing slag were also proposed as three steps involved: 1) the formation of calcium aluminates CaO•Al2O3 at the interface 2) the formation of 3CaO5Al2O3Ce2O3 as the reaction progresses; and 3) the dissolution of 3CaO5Al2O3Ce2O3 into the slag.…”
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Recursive seed amplification detects distinct α-synuclein strains in cerebrospinal fluid of patients with Parkinson’s disease by Stefan Bräuer, Iñaki Schniewind, Elisabeth Dinter, Björn H. Falkenburger

“…Prion-like properties of aSyn contribute to the spread of aSyn pathology throughout the nervous system as the disease progresses. Utilizing these properties, seed amplification assays (SAA) enable the detection of aSyn pathology in living patients. …”
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Association between Circulating Ectodysplasin A and Diabetic Kidney Disease by Xia Deng, Chang Guo, Huijuan Qin, Li Zhao, Yanyan Li, Zhicong Zhao, Haoxiang Li, Ling Yang, Dong Wang, Guoyue Yuan

“…EDA is positively correlated with the degree of albuminuria in patients with T2DM and may be involved in the occurrence and progression of diabetic kidney disease (DKD).…”
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Acute Transverse Myelitis (Ascending Myelitis) as the Initial Manifestation of Japanese Encephalitis: A Rare Presentation by Varshney Ankur Nandan, Kumar Nilesh, Behera Dibyaranjan, Tiwari Ashutosh, Anand Ravi, Anand Arvind

“…We hereby report a case of 13-year-old adolescent boy who presented to us with fever and acute onset paraparesis with urinary retention initially, progressing to quadriparesis and then followed by headache and altered sensorium. …”
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The Science of Disaster Medicine: From Response to Risk Reduction by Hüseyin Koçak, Kerem Kınık, Cüneyt Çalışkan, Kurtuluş Açıksarı

“…It is a discipline with slow scientific progress due to unclearly systematized multidisciplinary structure and sub-study areas. …”
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Assessing bias and computational efficiency in vision transformers using early exits by Seth Nixon, Pietro Ruiu, Marinella Cadoni, Andrea Lagorio, Massimo Tistarelli

“…The field has seen progressively deeper, more complex models or larger, more highly variant data sets. …”
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An Improved Registration Method for UAV-Based Linear Variable Filter Hyperspectral Data by Xiao Wang, Chunyao Yu, Xiaohong Zhang, Xue Liu, Yinxing Zhang, Junyong Fang, Qing Xiao

“…Even after geometric processing, adjacent flight lines still exhibit varying degrees of geometric deformation. In this paper, a progressive grouping-based strategy for iterative band selection and registration is proposed. …”
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Compensatory synaptotagmin-11 expression conceals parkinson’s disease-like phenotypes in parkin knockout mice by Nan Dong, Zhenli Xie, Anqi Wei, Yuxin Yang, Yongning Deng, Xu Cheng, Bianbian Wang, Yang Chen, Yuhao Gu, Jingyu Yao, Yuhao Qin, Chaowen Zheng, Xi Zhang, Yuqing Zhang, Xinjiang Kang, Guoqing Chen, Qiumin Qu, Changhe Wang, Huadong Xu

“…Therefore, this work not only elucidate a compensatory mechanism that accounts for the absence of overt PD phenotypes in parkin KO mice, but also contribute to the comprehensive understanding of the progression of PD, opening new avenues for the therapeutic treatment of PD.…”
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Myofibroblast-derived exosomes enhance macrophages to myofibroblasts transition and kidney fibrosis by Wenqiang Yu, Jinfang Song, Shuangquan Chen, Jiayi Nie, Chujun Zhou, Jiamin Huang, Hua Liang

“…However, the role of myofibroblast-derived exosomes in the process of MMT and renal fibrosis progression remains unknown. Here, we examined the role of myofibroblast-derived exosomes in MMT and kidney fibrogenesis. …”
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Effects of the Shape and Size of Irregular Particles on Specific Breakage Energy under Drop Weight Impact by Deqing Gan, Feng Gao, Yunpeng Zhang, Jinxia Zhang, Fusheng Niu, Ze Gan

“…Experimental studies indicate that the shape of particles significantly influences the impact loading mode and breakage progress; the specific breakage energy has an obvious relationship with the sphericity and the initial size. …”
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Unveiling FOXO3's metabolic contribution to menopause and Alzheimer's disease by Christopher O'Mahony, Oscar Hidalgo-Lanussa, George E. Barreto

“…This review aims to open a discussion on FOXO3's contribution to the metabolic dysregulation seen in menopause and its impact on the progression of AD. Understanding the functional role of FOXO3 in menopause-associated metabolic changes could lead to targeted therapeutic strategies, offering novel insights for managing for this condition.…”
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A practical guide for nephrologist peer reviewers: understanding and appraising Mendelian randomization studies by Jianbo Qing, Yafeng Li, Karim M. Soliman, Wisit Cheungpasitporn

“…Identifying risk factors for disease onset and progression has been a core focus in nephrology research. …”
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Health promoting activities and corresponding mechanism of (–)-epicatechin-3-gallate by Zhiliang Li, Changchun Feng, Hongjin Dong, Weibin Jin, Wenying Zhang, Jianfeng Zhan, Shuzhen Wang

“…The antineoplastic mechanism contains inhibition of phase 1 CYP enzymes, induction of phase II detoxification and antioxidant enzymes, high anti-inflammatory efficacy, arrest of cell cycle progression, regulation of apoptosis, as well as mediation of metastasis processes. …”
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Analysis of the skin layers and its appendages of developing human fetuses at different trimesters of pregnancy by Kumar Megur Ramakrishna Bhat, FK Febina, Lokadolalu Chandrachar Prasanna

“…Results: The epidermis architecture progresses from squamous layered to well-differentiated cellular layers in the third trimester. …”
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Advances in Pure Drug Self-Assembled Nanosystems: A Novel Strategy for Combined Cancer Therapy by Runyan Niu, Xuexue Liu, Xian Yang, Xiao Du, Siliang Wang, Xiaolong Ma, Shaoping Yin, Lihua Shao, Jinping Zhang

“…This review comprehensively explores recent progress in the application of PDANSs for cancer therapy. …”
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Synergistic recovery of Pr, Eu, and Ce from gold mine tailings using bioleaching and oxalic acid pretreatment by Hoda Fereydouni, Tannaz Naseri, Seyyed Mohammad Mousavi

“…Surface modifications revealed by structural analysis validated the progress of the bioleaching procedure. Based on kinetic modeling, it was determined that chemical reactions determined the rate-limiting stage. …”
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Combined Methods for Diabetic Retinopathy Screening, Using Retina Photographs and Tear Fluid Proteomics Biomarkers by Zsolt Torok, Tunde Peto, Eva Csosz, Edit Tukacs, Agnes M. Molnar, Andras Berta, Jozsef Tozser, Andras Hajdu, Valeria Nagy, Balint Domokos, Adrienne Csutak

“…It is estimated that 347 million people suffer from diabetes mellitus (DM), and almost 5 million are blind due to diabetic retinopathy (DR). The progression of DR can be slowed down with early diagnosis and treatment. …”
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Kinetic Analysis of 2-[C]Thymidine PET Imaging Studies of Malignant Brain Tumors: Preliminary Patient Results by Joanne M. Wells, David A. Mankoff, Janet F. Eary, Alexander M. Spence, Mark Muzi, Finbarr O'Sullivan, Cheryl B. Vernon, Jeanne M. Link, Kenneth A. Krohn

“…2-[ 11 C]Thymidine (TdR), a PET tracer for cellular proliferation, may be advantageous for monitoring brain tumor progression and response to therapy. Kinetic analysis of dynamic TdR images was performed to estimate the rate of thymidine transport ( K 1t ) and thymidine flux ( K TdR ) into brain tumors and normal brain. …”
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Role of exhaled hydrogen sulfide in the diagnosis of colorectal cancer by Jian Chen, Yujen Tseng, Peizhun Du, Pengcheng Liu, Huilu Zhang, Guangjian Huang, Cheng’en Hu

“…The exhaled H2S in patients with CRC was correlated with gender, lesion location and tumour progression, including depth of invasion, lymphatic metastasis and TNM (Tumor, Lymph Nodes, Metastasis) staging.Conclusion Exhaled H2S analysis is a convenient and non-invasive detection method for diagnosing CRC, suggesting a potential role in population screening for CRC.…”
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