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11541
Uncovering functional lncRNAs by scRNA-seq with ELATUS
Published 2024-11-01“…We independently confirm the expression patterns of cell type-specific lncRNAs exclusively detected with ELATUS and unveil biologically important lncRNAs, such as AL121895.1, a previously undocumented cis-repressor lncRNA, whose role in breast cancer progression is unnoticed by traditional methodologies. …”
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11542
Powdery mildew resistance of barley in Southern Dagestan
Published 2021-04-01“…The high level of disease progress observed annually helps to reliably assess the resistance of collection accessions to the pathogen.Materials and methods. …”
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11543
Lactylation modulation identifies key biomarkers and therapeutic targets in KMT2A-rearranged AML
Published 2025-01-01“…This variant is highly aggressive, characterized by rapid disease progression and poor outcomes. Growing knowledge of epigenetic changes, especially lactylation, has opened new avenues for investigation and management of this subtype. …”
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11544
Nutritional and medicinal characteristics of Chinese giant salamander (Andrias davidianus) for applications in healthcare industry by artificial cultivation: A review
Published 2018-03-01“…However, in the past twenty years, with the breakthrough and progress of artificial breeding technology by artificial insemination, the number of artificially cultivated CGS has increased rapidly. …”
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11545
Mechanistic relationship between obesity-induced inflammation triggering endothelial dysfunction and the initiation of atherosclerosis development
Published 2025-01-01“…The aim of this review is to summarize the effects of obesity-related inflammation on ED and its progression to atherosclerosis, focusing on cellular senescence, vascular aging, epigenetic modifications, reactive oxygen species, vascular calcification, and gut microbiota. …”
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11546
A Novel Association of Polymorphism in the ITGA4 Gene Encoding the VLA-4 α4 Subunit with Increased Risk of Alzheimer’s Disease
Published 2018-01-01“…Many studies support the hypothesis that the inflammation of the CNS contributes to the neurodegeneration and disease progression. The integrin molecule α4β1, also known as very late antigen 4 (VLA-4), belongs to adhesion molecules that activate the inflammatory process through the migration of immune cells into the CNS. …”
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11547
Immersion in Complex Dynamical Systems with Ergodicity
Published 2024-04-01“…Beginning with an exposition of fundamental concepts in dynamical systems theory, particular attention is given to topological dynamical systems (TDS). The discussion progresses to explore discrete topological entropy and its significance within dynamical systems, culminating in the introduction of topological entropy pressure as a nuanced form of this concept. …”
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11548
"ALL ANIMALS ARE EQUAL, BUT SOME ANIMALS ARE MORE EQUAL THAN OTHERS": THE NEGTIVE IMPACT OF GENDER INEQUALITY ON THE GLOBAL ECONOMY AND PUBLIC HEALTH
Published 2019-06-01“…Outdated gender roles, which are inconsistent with the new reality and the idea of human progress, have a significant impact on life expectancy, health, mortality and disease, access to health care and medical care. …”
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11549
Fast Fault-Tolerant Grid Frequency Measurement
Published 2024-01-01“…With inverter-based generation progressively displacing traditional synchronous generators, power systems generally experience increased rate of change of grid frequency and wider propagation of voltage disturbances after a network contingency event. …”
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11550
Cross-sectional study of the association between cataract surgery and age-related macular degeneration in the era of phacoemulsification in the national health and nutrition examin...
Published 2020-09-01“…Longitudinal studies investigating the risk and progression of AMD after cataract surgery are needed in the era of phacoemulsification.…”
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11551
Neural Mass Modeling in the Cortical Motor Area and the Mechanism of Alpha Rhythm Changes
Published 2024-12-01“…Investigating the physiological mechanisms in the motor cortex during rehabilitation exercises is crucial for assessing stroke patients’ progress. This study developed a single-channel Jansen neural mass model to explore the relationship between model parameters and motor cortex mechanisms. …”
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11552
Circadian Rhythms and Breast Cancer: The Role of Per2 in Doxorubicin-Induced Cell Death
Published 2015-01-01“…Circadian disruptions have been implicated in the onset and progression of various cancers, including those arising in the breast. …”
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11553
Neural Induction, Neural Fate Stabilization, and Neural Stem Cells
Published 2002-01-01“…An underlying biological reason for the progressive functional losses associated with these diseases is the extremely low natural rate of self-repair in the nervous system. …”
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11554
Lipidomics of Huntington’s Disease: A Comprehensive Review of Current Status and Future Directions
Published 2025-01-01“…Background: Huntington’s disease (HD) is a multifaceted neurological disorder characterized by the progressive deterioration of motor, cognitive, and psychiatric functions. …”
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11555
Influence of Preoperative Pain Duration on Microsurgical Varicocelectomy Outcomes
Published 2013-01-01“…Total sperm concentration (TSC), rapidly progressive motility (SPa), and slow or sluggish motility (SPb) rates were noted. …”
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11556
Sub-technology market share strongly affects critical material constraints in power system transitions
Published 2025-02-01“…Solar photovoltaic and wind power sub-technology market shares have the greatest impact on critical material demand. As progressive thin-film solar photovoltaic sub-technologies gain market share, the demand for gallium from solar photovoltaic may increase 56-fold. …”
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11557
Penguatan profil pelajar pancasila melalui self-regulated learning (SRL) pada siswa sekolah luar biasa (SLB)
Published 2024-11-01“…Education plays an important role in shaping the character and personality of individuals and society, so that it becomes one of the determinants of national progress. The Minister of Education and Culture Regulation stipulates that currently one of the focuses of education in Indonesia is developing a student profile based on Pancasila values. …”
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11558
Establishment of reference audiometric norms for the elderly population: A community-based study on mean and median hearing thresholds
Published 2025-01-01“…The study illuminated a progressive increase in hearing thresholds with age and higher frequencies. …”
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11559
BMP4 Cooperates with Retinoic Acid to Induce the Expression of Differentiation Markers in Cultured Mouse Spermatogonia
Published 2016-01-01“…Immunostaining showed that BMP4 was predominantly expressed in germ cells and that its level increased as spermatogenesis progresses. BMP4 receptors BMPR1A and BMPRII were present in spermatogonia, spermatocytes, and round spermatids. …”
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11560
Flt3 Regulation in the Mononuclear Phagocyte System Promotes Ocular Neovascularization
Published 2018-01-01“…Increased Flt3 expression at the protein level was detected in retinas of oxygen-induced retinopathy (OIR) mice at P15 and P18 during retinal NV (RNV) progression. We subsequently found that macrophages (Mphi) polarization was regulated at the site of CNV in Flt3-deficient mice. …”
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