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11521
Safety and Efficacy of Anticoagulation in Patients with Cirrhosis: A Meta-Analysis
Published 2021-01-01“…Recanalization and thrombus progression were defined as the primary outcomes. Secondary outcomes included adverse events and death mortality. …”
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11522
Characteristics of Pressure Relief Gas Extraction in the Protected Layer by Surface Drilling in Huainan
Published 2021-01-01“…Specifically, it is affected by factors such as the mining progress of the working face of the protective layer, mining height, degree of compacted goaf, degree of pressure relief of the protected layer, original gas content, and other measures taken to extract the protected layer.…”
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11523
Gastrointestinal Bleeding and Diffuse Skin Thickening as Kaposi Sarcoma Clinical Presentation
Published 2015-01-01“…However, since March 2014, renal function progressively deteriorated. A second allograft biopsy showed no new lesions. …”
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11524
Intra-Bone Marrow Administration of Mesenchymal Stem/Stromal Cells Is a Promising Approach for Treating Osteoporosis
Published 2019-01-01“…However, it is not known if MSCs are effective for treating systemic bone diseases, as the risk for mortality following intravenous MSC administration has hindered research progress. In this study, we compared the safety and efficacy of intra-bone marrow and intravenous administration of MSCs for the treatment of ovariectomy- (OVX-) induced osteoporosis. …”
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11525
Macrophage-inherited exosome excise tumor immunosuppression to expedite immune-activated ferroptosis
Published 2023-05-01“…M1 macrophage-derived exosomes can inherit more functions and genetic substances than nanovesicles since nanovesicles inevitably suffer from substance and function loss caused by extrusion-arised structural damage.Results Inspired by it, spontaneous homing to tumor and M2-like macrophage polarization into M1-like ones are attained, which not only significantly magnify oxidative stress but also mitigate ITM including M2-like macrophage polarization and regulatory T cell decrease, and regulate death pathways.Conclusions All these actions accomplish a synergistic antitumor enhancement against tumor progression, thus paving a general route to mitigate ITM, activate immune responses, and magnify ferroptosis.…”
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11526
From Location Advantage to Innovation: Exploring Interprovincial Co-Funding Networks in Mainland China
Published 2025-01-01“…This improved equilibrium has positively influenced regional scientific output, demonstrating that a province’s position within the co-funding network—particularly its individual location advantage—plays a pivotal role in advancing technological progress. However, persistent disparities in regional collaboration and development remain, underscoring the need for more coordinated strategies to address uneven growth dynamics. …”
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11527
Plasma proteome fingerprint in kidney diseases
Published 2025-01-01“…Patients with kidney diseases are often asymptomatic until disease progression starts. Expensive renal replacement therapy options, such as dialysis or kidney transplant, are required for end-stage kidney disease. …”
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11528
Blood-based biomarkers in mild behavioral impairment: an updated overview
Published 2025-02-01“…These findings offer insights into the underlying pathophysiology of MBI, and connection between neuropsychiatric symptoms and progression of AD. In this narrative review, we aim to summarize and critically discuss the emerging literature evidence linking MBI to blood-based biomarkers, hoping to shed more light on MBI’s pathophysiology, its connection to AD-related neurobiology, as well as its potential practical utility for predicting cognitive impairment, guiding early interventions and managing the risk for dementia.…”
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11529
Methadone-Induced Delayed Posthypoxic Encephalopathy: Clinical, Radiological, and Pathological Findings
Published 2010-01-01“…After 2 weeks from discharge he had progressive deterioration of his cognitive, behavioral and neurological function. …”
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11530
A Foreign Speech Accent in a Case of Conversion Disorder
Published 2005-01-01“…This accent had persisted over the past eight years and has become progressively stronger. The foreign qualities of her speech did not only relate to pronunciation, but also to the lexicon, syntax and pragmatics. …”
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11531
A Case of Acute Disseminated Encephalomyelitis in a Middle-Aged Adult
Published 2015-01-01“…Encephalopathy and focal neurological deficits are usually manifest several weeks after a prodromal illness with rapidly progressive neurologic decline. ADEM is most commonly seen in children and young adults, in which prognosis is favorable, but very few cases have been reported of older adults with ADEM and thus their clinical course is unknown. …”
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11532
High-rate quantum LDPC codes for long-range-connected neutral atom registers
Published 2025-01-01“…Recently, quantum error correction has experienced significant progress both in code development and experimental realizations, with neutral atom qubit architecture rapidly establishing itself as a leading platform in the field. …”
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11533
Mesenchymal stem cells and their extracellular vesicle therapy for neurological disorders: traumatic brain injury and beyond
Published 2025-02-01“…This review explores the progress and prospects of MSC therapy in TBI, focusing on mechanisms of action, therapeutic benefits, and the challenges and potential limitations of using MSCs in treating neurological disorders.…”
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11534
Prevalence of CagA-positive Helicobacter pylori strain and H. pylori-associated gastritis activity in Tuva schoolchildren of different age groups
Published 2018-08-01“…The received results demonstrate that development, course and progression of CagA-positive H. pylori associated gastritis is affected by genetic (ethnic) features of the host.…”
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11535
Optical Coherence Tomography (Angiography) Biomarkers in the Assessment and Monitoring of Diabetic Macular Edema
Published 2020-01-01“…Retinopathy is one of the most severe diabetes-related complications, and macular edema is the major cause of central vision loss in patients with diabetes mellitus. Significant progress has been made in recent years in optical coherence tomography and angiography technology. …”
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11536
Machado-Joseph Disease, A Case Report of Treatment Based on Phototherapy
Published 2024-11-01“…A year later, as the disease progressed, he decided to resume the same scheme, and the following trends were observed: a) Improvement in role limitations due to physical health, emotional well-being, social functioning, and general health; b) No changes in role limitations due to emotional problems and pain and c) deterioration in energy/fatigue.…”
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11537
Sex-Pheromone-Mediated Mating Disruption Technology for the Oriental Fruit Moth, Grapholita molesta (Busck) (Lepidoptera: Tortricidae): Overview and Prospects
Published 2014-01-01“…A great deal of progress has been made over the last three decades in research on pheromone-mediated mating disruption technology for the oriental fruit moth, Grapholita molesta (Busck). …”
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11538
USP20 mediates malignant phenotypic changes in bladder cancer through direct interactions with YAP1
Published 2025-02-01“…The Hippo-YAP1 axis is inhibited in bladder cancer (BC), which is a major driver of BC progression and oncogenesis. Hippo pathway activity is controlled by the phosphorylation cascade in the MST1/2-LATS1/2-YAP1 axis, in addition to other modifications such as ubiquitination of the Hippo pathway proteins through the co-regulation of E3 ligases and deubiquitinases. …”
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11539
TClC effectively suppresses the growth and metastasis of NSCLC via polypharmacology
Published 2025-03-01“…TClC disrupts autocrine loops that promote tumor progression, particularly in stem-like CD133-positive NSCLC (CD133+ LC) cells, which are pivotal in tumor metastasis. …”
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11540
Cortical arealization of interneurons defines shared and distinct molecular programs in developing human and macaque brains
Published 2025-01-01“…Overall, our analyses depict the spatiotemporal features appended to cortical interneurons, providing a new proxy for understanding the relationship between cellular diversity and functional progression.…”
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