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11441
Influence of ethnicity on cyclin-dependent kinase inhibitor efficacy and toxicity: A systematic review and meta-analysis
Published 2025-02-01“…We included studies comparing CDK4/6i (palbociclib, ribociclib, abemaciclib, dalpiciclib) + ET versus placebo + ET. Progression-free survival (PFS) and overall survival (OS), hazard ratios (HR), and 95 % confidence intervals (CI) were extracted for the two subgroups of interest. …”
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11442
Outcomes with bridging radiation therapy prior to chimeric antigen receptor T-cell therapy in patients with aggressive large B-cell lymphomas
Published 2025-01-01“…Median overall survival (OS) was 22.1 months (6.6-not reached) and the median progression-free survival (PFS) was 7.4 months (5.5-30). …”
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11443
Cancer cells avoid ferroptosis induced by immune cells via fatty acid binding proteins
Published 2025-02-01“…Clinical trial data revealed that higher FABP7 expression correlates with poorer overall survival and progression-free survival in patients undergoing immunotherapy. …”
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11444
SLC31A1 promotes chemoresistance through inducing CPT1A-mediated fatty acid oxidation in ER-positive breast cancer
Published 2025-03-01“…RNA-Seq analysis indicated that FAO might be implicated in SLC31A1-mediated breast cancer progression. CPT1A was also overexpressed in TAM-resistant breast cancer cells, accompanied by enhanced FAO rates and ATP levels. …”
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11445
Presenting the model of managerial competencies of women in the industry (case study: Sabah Food Company)
Published 2024-09-01“…Despite the decades of progress of women in obtaining university degrees and holding managerial positions, women are still a small minority in the field of organization management and leadership. …”
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11446
Studying the Oncolytic Activity of <i>Streptococcus pyogenes</i> Strains Against Hepatoma, Glioma, and Pancreatic Cancer <i>In Vitro</i> and <i>In Vivo</i>
Published 2025-01-01“…Increased lifespan was accompanied by a slowdown in tumor progression, as evidenced by a reduction in the growth of hepatoma and pancreatic cancer tumors under treatment with GAS strains in mice. …”
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11447
A simple staging system using biomarkers for wild‐type transthyretin amyloid cardiomyopathy in Japan
Published 2022-06-01“…This system can objectively evaluate the disease progression of ATTRwt‐CM and may be useful for patient selection for disease‐modifying therapy.…”
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11448
Elevating larval source management as a key strategy for controlling malaria and other vector-borne diseases in Africa
Published 2025-02-01“…However, the stagnation of progress towards malaria elimination demands that we consider additional options to the current emphasis on insecticidal commodities targeting adult mosquitoes inside homes. …”
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11449
Sex differences in the peripheral levels of cytokines during 12-month antipsychotic treatment in a drug-naïve schizophrenia spectrum cohort
Published 2025-03-01“…There were significant sex differences in progression of cytokine levels at weeks 3 (IL-6: p = 0.046), 6 (IL-4: p = 0.022, IL-6: p = 0.015), 12 (IL-6: p = 0.01), 26 (IL-4: p < 0.001, IL-6: p = 0.015, TNF-α: p = 0.026), 39 (IL-4: p = 0.003, TNF-α: p = 0.023) and 52 (IL-4: p < 0.001, TNF-α: p = 0.009). …”
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11450
Influence of Exposure to Different Green Rooftop Spaces on Stress Restoration of College Students
Published 2025-02-01“…ObjectiveAlong with the continuous progress of urbanization, the number of people living in cities is increasing. …”
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11451
La datation des aqueducs lyonnais : un état des lieux
Published 2023-12-01“…In recent decades, preventive archaeology operations as well as data from archaeometry (radiocarbon dating, archaeomagnetism and dendrochronology) have enabled progress to be made in understanding the chronology of these works. …”
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11452
Editorial
Published 2020-06-01“…All said, if fairness is about current generations having similar housing opportunities as their predecessors, access to affordable housing must be addressed. If progress is about ensuring that younger generations today have accessible housing paths so that one day they can help their own children launch, the intergenerational justice framework should push us to act even more quickly. …”
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11453
Combined Age with Mean Decrease Rates of Total Bilirubin and MELD Score as a Novel and Simple Clinical Predictor on 90-Day Transplant-Free Mortality in Adult Patients with Acute Li...
Published 2023-01-01“…Acute liver failure (ALF), previously known as fulminant hepatic failure, has become a common, rapidly progressive, and life-threatening catastrophic hepatic disease in intensive care unit (ICU) due to the continuous increase in drug abuse, viral infection, metabolic insult, and auto-immune cause. …”
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11454
Editorial
Published 2009-10-01“…The paper of Christoph Lumer (University of Siena, Italy) establishes a new criterion for our moral duties, dubbed ‘progressive norm welfarism’, and deduces a principle of ‘no harm to developing countries’ from it. …”
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11455
Podophyllotoxin mediates hepatic toxicity via the C5a/C5aR/ROS/NLRP3 and cGMP/PKG/mTOR axis in rats based on toxicological evidence chain (TEC) concept by phosphoproteomic analysis
Published 2025-01-01“…This approach transforms fragmented toxicity indicators into systematic evidence of toxicity, presenting a hierarchical progression of toxicity evidence and avoiding data accumulation in natural drug toxicology. …”
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11456
Analysis of the current situation and risk factors of frailty in elderly patients with type 2 diabetes (老年2型糖尿病患者衰弱现状及影响因素分析)
Published 2024-06-01“…Screening elderly patients with type 2 diabetes for early signs of frailty and addressing risk factors through specific interventions can help slow down the progression of frailty. (目的 调查老年2型糖尿病患者的衰弱现状, 分析潜在影响因素, 以期为相关干预研究提供参考依据。…”
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11457
Case Reports: The core of practice-based evidence
Published 2019-07-01“…It is well-recognized that scientific progress is based on upon observation, and it is supplemented by many experimentations. …”
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11458
Fálétí’s Philosophical Sensibility
Published 2021-12-01“…While Fágúnwà could not resist the influence of Christianity, and especially the allegorical motif of the journey in which humans encounter spiritual challenges (which John Bunyan’s Pilgrim Progress made popular), Fálétí is fundamentally a cultural connoisseur; a writer with a most intimate and dynamic understanding of the Yorùbá condition, especially in its conjunction with the political and sociocultural contexts of contemporary Nigeria. …”
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11459
Neurotoxicity of aluminium chloride and okadaic acid in zebrafish: Unravelling Alzheimer's disease model via learning and memory function evaluation
Published 2025-01-01“…Introduction/objectives: Alzheimer's disease (AD) is characterised by a progressive decline in cognitive abilities, especially learning and memory. …”
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11460
Evolution of Green Technology, Technology Gap and International Trade A Comparative Study of Developing and Developed Countries
Published 2024-12-01“…Aim and Introduction Trade is one of the most important factors for the economic progress of countries, which has become feasible with the globalization of business. …”
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