From pixels to prognosis: radiomics and AI in Alzheimer’s disease management by Danting Peng, Weiju Huang, Ren Liu, Wenlong Zhong

“…We discuss the potential of these technologies to identify disease-specific biomarkers, predict disease progression, and guide personalized interventions. Additionally, the review addresses critical challenges, including data standardization, model interpretability, and the integration of AI into clinical workflows. …”
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‘How the guineas shone as they came pouring out of the dark leather mouths!’: Shades of Gold in George Eliot’s Silas Marner (1861) by Marie-Laure Massei-Chamayou

“…At the end, the recovery of the stolen gold coins both leads to the emergence of the truth and works as a sign of divine reward for Silas’s spiritual progress. Such weaving of the multi-layered theme of gold into the narrative definitely gives birth to an effective poetics which may address several planes of consciousness.…”
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Mode-I Metal-Composite Interface Fracture Testing for Fibre Metal Laminates by Periyasamy Manikandan, Gin Boay Chai

“…The results of the experimental and numerical studies showed that metal plasticity increases the fracture energy of the metal-composite interface as the fracture event progresses. The applied energy truly utilized to propagate metal-composite interface fracture was predicted numerically by extracting the elastic strain energy data. …”
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Biometallic ions and derivatives: a new direction for cancer immunotherapy by Lin Zhao, Yajun Gui, Jing Cai, Xiangying Deng

“…In addition, biometallic ions and derivatives can directly inhibit tumor cell progression and offer the possibility of effectively overcoming the limitations of current cancer immunotherapy by promoting immune responses and reducing immunosuppressive signals. …”
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Analysis of Bio-Sorption of Cr(VI) onto Raw Rice Husk by a Hybrid Theoretical Model Using Results of Batch Experiments by Debasish Sarkar, Sudip K Das, Amitava Bandyopadhyay

“…A hybrid mathematical model that takes into account the shrinking core approach coupled with the well-known progressive conversion model has been proposed to simulate the dynamic behaviour of the present system using the results obtained from the batch adsorption experiments. …”
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A Case of an Unusually Aggressive Cutaneous Anaplastic Large T-Cell Lymphoma in an HIV Patient Treated with CHOP by Jorge Hurtado-Cordovi, Louay Hanna, Vladimir Gotlieb, Alan S. Multz, Anastasia Pigal

“…This case report describes an unusual rapidly progressing cutaneous anaplastic large T-cell lymphoma in an HIV patient. …”
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Mobilités socio-spatiales et production territoriale en Sénégambie by Mohamadou Mountaga Diallo

“…The strengthening or formalization of these local initiatives involves part of the ongoing decentralization process in Senegal and Gambia, and also reflects recent progress made by ECOWAS in the formalization of border cooperation. …”
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Challenges and solutions for the implementation of computer-based test learning evaluation at SMKN 2 Bandung by Azzahra Putri Imanda, Dea Apriliyani, Dewi Allyya Suci Putri Anjani

“…The integration of CBT reflects a progressive step toward advancing education assessment methodologies.…”
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A pan-orthohantavirus human lung xenograft mouse model and its utility for preclinical studies. by Melanie Rissmann, Danny Noack, Thomas M Spliethof, Vincent P Vaes, Rianne Stam, Peter van Run, Jordan J Clark, Georges M G M Verjans, Bart L Haagmans, Florian Krammer, Marion P G Koopmans, Judith M A van den Brand, Barry Rockx

“…This pan-orthohantavirus model will facilitate progress in the fundamental understanding of pathogenesis and virus-host interactions for orthohantaviruses. …”
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Victus Exergame: An Approach to Rehabilitation of Amputees Based in Serious Game by Rafael Luz Melo, Vítor da Silva Moreira, Érico Marcelo Hoff do Amaral, Julio S. Domingues Júnior

“…That system serves as both the game controller and a set of biological monitors, alongside a physiotherapy tool that displays the data obtained during sessions for the therapists to track patient progress. Developed through a participatory design approach involving patients and therapists, the system collects data on user engagement, physiological responses, and performance metrics via sensors and feedback forms. …”
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Severe invasive streptococcal infection in a patient with COVID-19: A case report by Yuki Matsuura, Mone Murashita, Takayoshi Oyasu, Akira Kodate, Yoshihiro Sadamoto, Akio Endo, Hisako Sageshima, Takumi Tsuchida

“…However, multiple organ failure progressed, and the patient died one day after admission. …”
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The Role of Noncoding RNA in Airway Allergic Diseases through Regulation of T Cell Subsets by Shenghao Cheng, Qingping Tang, Shaobing Xie, Sihui Wen, Hua Zhang, Zhihai Xie, Weihong Jiang

“…Mounting evidence suggested that epigenetic alterations were strongly associated with the progression and severity of allergic diseases. Noncoding RNAs (ncRNAs) are a class of transcribed RNA molecules that cannot be translated into polypeptides and consist of three major categories, microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs). …”
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Lessons from a Mouse Model Characterizing Features of Vascular Cognitive Impairment with White Matter Changes by Masafumi Ihara, Hidekazu Tomimoto

“…With the demographic shift in age in advanced countries inexorably set to progress in the 21st century, dementia will become one of the most important health problems worldwide. …”
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Catecholaminergic dysfunction drives postural and locomotor deficits in a mouse model of spinal muscular atrophy by John G. Pagiazitis, Nicolas Delestrée, Leonie Sowoidnich, Nandhini Sivakumar, Christian M. Simon, Athanasios Chatzisotiriou, Maria Albani, George Z. Mentis

“…SMA is characterized by severe motor dysfunction and postural deficits. We identify progressive loss of catecholaminergic synapses from spinal neurons that occur via non-cell autonomous mechanisms. …”
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A Survey on Sensor Selection and Placement for Connected and Automated Mobility by Mehmet Kiraz, Fikret Sivrikaya, Sahin Albayrak

“…The progress towards fully autonomous mobility is significantly impacted by the integration of evolving technologies in connected and automated mobility (CAM). …”
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Expression of Integrin Alpha10 Is Induced in Malignant Melanoma by Ann-Kathrin Wenke, Christian Kjellman, Evy Lundgren-Akerlund, Christian Uhlmann, Nikolas K. Haass, Meenhard Herlyn, Anja K. Bosserhoff

“…Further, we demonstrated that expression of integrin alpha10 is controlled by AP-2 and Ets-1, two transcription factors known to be involved in melanoma development and progression. To investigate the functional relevance of integrin alpha10, expression was downregulated via stable antisense transfection. …”
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The synthesis and research of the naphthalimide G-quadruplex probe targeting hybrid G4s by Lilin Gan, Wenzheng Luo, Qian Cheng, Shanke Wan, Min Wu, Mingqi Wang, Enming Luo, Xianjin Luo, Shuo Li

“…Nevertheless, the effectiveness of the traditional small-molecule fluorescent probe targeting G4 was hindered by limitations in single function and low selectivity, and progress in anti-tumor research was impeded. In this study, a novel naphthalimide probe（AI7）was synthesized and reported for hybrid G4 structures targeting, and 3–10 times fluorescence intensity was increased by the interaction with hybrid G4 structures. …”
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The Future of Asthma Treatment by Louis-Philippe Boulet

“…In the past few years, significant progress has been made in the treatment of asthma with the development of bronchodilators with longer durations of action, more concentrated inhaled steroid formulations and new modes of administering antiasthma medication. …”
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Intradural Extramedullary Capillary Hemangioma in the Upper Thoracic Spine: A Review of the Literature by Yoichiro Takata, Toshinori Sakai, Kosaku Higashino, Yuichiro Goda, Fumitake Tezuka, Koichi Sairyo

“…We report here a 60-year-old man presenting with thoracic girdle pain and progressive gait disturbance. Magnetic resonance images of the thoracic spine showed a 12×8×20 mm, well-defined intradural mass at the T2 level, compressing the spinal cord laterally. …”
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Advancements in surface-enhanced femtosecond stimulated Raman spectroscopy: exploring factors influencing detectability and shapes of spectra by Pyrcz Patryk, Gawinkowski Sylwester

“…During the initial successful implementations of this approach, unexpected spectral distortions were observed, and several potential explanations were proposed. Further progress in this novel technique and its broader implementation requires a profound understanding of the factors influencing the shape of the registered spectra and the underlying mechanisms. …”
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