Spatiotemporal schemas of progress and stasis in Rose Macaulay’s Told by an Idiot: on moving forward and going round by Craig Melhoff

Get full text

Polymorphism of renin — angiotensin system genes in progression of liver fibrosis in patients with chronic hepatitis C by O. V. Taratina, T. N. Krasnova, L. M. Samokhodskaya, T. N. Lopatkina, V. A. Tkachuk, N. A. Mukhin

“…Overall 109 patients with CHC and liver cirrhosis C with established stage of fibrosis and duration of disease have been divided into group of «rapidly progressing fibrosis» (55 patients, ≥0,130 fibrosis points/year) and «slowly progressing fibrosis» (54 persons, <0,130 fibrosis units/year). …”
Get full text

Local Gene Transfer of OPG Prevents Joint Damage and Disease Progression in Collagen-Induced Arthritis by Qingguo Zhang, Weiming Gong, Bin Ning, Lin Nie, Paul H. Wooley, Shang-You Yang

“…Histological assessment demonstrated that OPG gene transfer dramatically protected mice from erosive joint changes compared with LacZ controls (P<0.05), although treatment appeared less effective on the local inflammatory progress. MicroCT data suggested significant protection against subchondral bone mineral density changes in OPG treated CIA mice. …”
Get full text

Do Unresectable Giant Cell Tumors of Bone Treated With Denosumab Progress After Discontinuation of Treatment? by DENO Research Group, Carolina de laCalva, Manuel Angulo, Paula González‐Rojo, Ana Peiró, Pau Machado, Juan Luis Cebrián, Roberto García‐Maroto, Antonio Valcárcel, Pablo Puertas, Gregorio Valero‐Cifuentes, Óscar Pablos, Miriam Maireles, María Luisa Fontalva, Iván Chaves, Aida Orce, Luis Coll‐Mesa, Israel Pérez, Fausto González, María delCarmen Sanz, Isidro Gracia

“…Four patients experienced local progression, and one presented multifocal progression. …”
Get full text

Does Cataract Surgery Improve the Progression of Age-Related Macular Degeneration? A Meta-Analysis by Yuanyuan Liu, Qinhua Cai

“…In random effects model, the relative risk (RR) for the progression of AMD is 1.194 (95% CI 0.897–1.591). As for those grouped according to the follow-up year, the RR for longer than five years was 1.372 (95% CI 1.062–1.772). …”
Get full text

Single-cell RNA sequencing revealed PPARG promoted osteosarcoma progression: based on osteoclast proliferation by Lei Sun, Jinhao Zhang, Zhikai Xiahou, Zhenzhen Zhao, Yanchen Liang

“…A large number of studies confirmed that osteoclasts are an important part of OS, which play an active role in destroying bone homeostasis and promoting the progress of OS. Therefore, we conducted a detailed study of osteoclasts at the single cell level, aiming to find new OS therapeutic targets to prevent tumor progression and local spread.MethodsWe analyzed the single-cell sequencing data of OS patients and usedMonocle2, Cytotrace, and Slingshot software to analyze the pseudo-sequential trajectory during OS progression. …”
Get full text

Predictors of Cardiovascular Autonomic Neuropathy Onset and Progression in a Cohort of Type 1 Diabetic Patients by M. Matta, A. Pavy-Le Traon, S. Perez-Lloret, C. Laporte, I. Berdugo, N. Nasr, H. Hanaire, J. M. Senard

“…However, the rate and predictors of both the development and progression of CAN have been less studied. Hereby, we assessed the rate and the major risk factors for CAN initiation and progression in a cohort of type 1 diabetic patients followed over a three-year period. …”
Get full text

Investigating Lexical Progression through Lexical Diversity Metrics in a Corpus of French L3 by Paula Lissón, Nicolas Ballier

“…This article presents a corpus-based evaluation of 13 lexical diversity metrics as measures of longitudinal progression in written productions of learners of French as third language (L3). …”
Get full text

Recent Progress on the Implementation of Renewable Biodiesel Fuel for Automotive and Power Plants: Raw Materials Perspective by Jayan Sentanuhady, Wisnu Hozaifa Hasan, Muhammad Akhsin Muflikhun

Get full text

Different Levels of Autophagy Activity in Mesenchymal Stem Cells Are Involved in the Progression of Idiopathic Pulmonary Fibrosis by Hongxia Tao, Qin Lv, Jing Zhang, Lijuan Chen, Yang Yang, Wei Sun

“…However, MSCs lose their repair functions due to their distinctive aging characteristics, eventually leading to the progression of IPF. Recent breakthroughs have revealed that the degree of autophagic activity influences the renewal and aging of MSCs and determines the prognosis of IPF. …”
Get full text

Progression of ampC amplification during de novo amoxicillin resistance development in E. coli by Luyuan Nong, Martijs Jonker, Wim de Leeuw, Meike T. Wortel, Benno ter Kuile

“…Here, we study the progression of ampC amplification and ampC promoter mutations during the evolution of resistance induced by stepwise increasing amoxicillin concentrations. …”
Get full text

Progress in the Relationship between Vitamin D Deficiency and the Incidence of Type 1 Diabetes Mellitus in Children by Lian-Ping He, Yu-Xin Song, Ting Zhu, Wei Gu, Chang-Wei Liu

Get full text

Analysis of Progress and Challenges of EGFR-Targeted Molecular Imaging in Cancer With a Focus on Affibody Molecules by Weizhi Chen MD, Baozhong Shen MD, PhD, Xilin Sun PhD

Get full text

Transmission of unfolded protein response—a regulator of disease progression, severity, and spread in virus infections by Vibhu Prasad

Subjects: Get full text

Pivotal roles of Plasmodium falciparum lysophospholipid acyltransferase 1 in cell cycle progression and cytostome internalization by Junpei Fukumoto, Minako Yoshida, Suzumi M. Tokuoka, Eri Saki H. Hayakawa, Shinya Miyazaki, Takaya Sakura, Daniel Ken Inaoka, Kiyoshi Kita, Jiro Usukura, Hideo Shindou, Fuyuki Tokumasu

“…Here, we identify P. falciparum lysophospholipid acyltransferase 1 (PfLPLAT1) and show that PfLPLAT1 is vital for asexual parasite cell cycle progression and cytostome internalization. Deficiency in PfLPLAT1 results in decreased parasitemia and prevents transition to the schizont stage. …”
Get full text

The Role of the Microbiome and Intestinal Mucosal Barrier in the Development and Progression of Non-Alcoholic Fatty Liver Disease by T. S. Krolevets, M. A. Livzan, S. I. Mozgovoy

“…To review available data on the role of the microbiome and intestinal mucosal barrier in the development and progression of non-alcoholic fatty liver disease (NAFLD).Key points. …”
Get full text

The advancement of primary care dentistry in Hungary: progress of the dental cluster model since 2021 legislation by András Sztrilich, Csilla Kaposvári, Csilla Kaposvári, Csilla Kaposvári, Gergő Túri, Gergő Túri, Gergő Túri, Rita Teller, István Vingender

“…This study aims to describe the advancement of primary care dentistry in Hungary and the progress of the dental cluster model since the 2021 legislation.MethodsA mixed method study was designed that included a scoping review of the literature in December 2023 to collect information on the health policy developments of Hungary’s publicly funded primary dental care system; (b) secondary data analysis was carried out to assess the development of primary care dentistry and the formation and operation of dental cluster practices in Hungary.ResultsPrimary care dental clusters in Hungary were established to allow active professional cooperation within the dental clusters to improve the population’s access to preventive dental services and the quality of services. …”
Get full text

The Multifaceted Role of Extracellular Vesicles in Glioblastoma: microRNA Nanocarriers for Disease Progression and Gene Therapy by Natalia Simionescu, Radu Zonda, Anca Roxana Petrovici, Adriana Georgescu

“…In this review, we discuss the role of EVs and their miRNA content in GB progression and resistance to therapy, with emphasis on their potential as diagnostic, prognostic and disease monitoring biomarkers and as nanocarriers for gene therapy.…”
Get full text

Hubungan Antara Cache, Energy Consumption dan Runtime Performance pada Progressive Web Apps by Wakhid Kurniawan, Agung Fatwanto

“…The presence of Progressive Web Apps has a positive impact on Web developers, whose advantages provide a significant increase in performance. …”
Get full text

Research Progress on Nutritional Characteristics, Taste Quality Improvement and Functional Evaluation of Germinated Brown Rice by REN Chuanying, HONG Bin, ZHANG Shan, YUAN Di, FENG Junran, SHAN Shan, ZHANG Jingyi, GUAN Lijun, LI Bo, HUANG Wengong, LU Shuwen

Get full text