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7241
Modulating tumor-associated macrophages through CSF1R inhibition: a potential therapeutic strategy for HNSCC
Published 2025-01-01“…Depending on the context, TAMs can either suppress tumor progression and weaken drug sensitivity or facilitate tumor growth and drive therapeutic resistance. …”
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7242
LncRNA-ANRIL regulates CDKN2A to promote malignant proliferation of Kasumi-1 cells
Published 2025-01-01“…Co-transfection experiments showed that simultaneous cyclin D1 suppression and ANRIL overexpression attenuated ANRIL’s stimulatory effects on cell cycle progression. RIP analysis confirmed a physical interaction between ANRIL and CDKN2A. …”
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7243
Neonatal indicator data in Tanzania District Health Information System: evaluation of availability and quality of selected newborn indicators, 2015-2022
Published 2025-01-01“…The District Health Information System (DHIS2), an open-source platform in over 80 countries, supports health data collection and analysis, enabling progress tracking at national and subnational levels. …”
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7244
The genetic duet of concurrent RASAL1 and PTEN alterations promotes cancer aggressiveness by cooperatively activating the PI3K–AKT pathway
Published 2025-01-01“…This was enhanced by additional tumor protein p53 (TP53) gene alterations, with cancer progression and mortality rates being 47.65% and 34.46% with coexisting RASAL1, PTEN, and TP53 alterations versus 25.30% and 13.11% with no alteration (HR 2.21, 95% CI 1.92–2.56 and 2.76, 95% CI 2.31–3.30), respectively. …”
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7245
Microenvironment Influences on Human Umbilical Cord Mesenchymal Stem Cell-Based Bone Regeneration
Published 2021-01-01“…In the in vitro three-dimensional culture microenvironment, nHAC/PLA supported hUC-MSCs’ adhesion, proliferation, and differentiation; the microenvironment containing OMD or OMD and rhBMP-7 shortened cell proliferation progression and made osteogenic differentiation progression advance; rhBMP-7 significantly attenuated the inhibiting effect of OMD on hUC-MSCs’ proliferation and significantly enhanced the promoting effect of OMD on gene expression and protein secretion of osteogenic differentiation markers, calcium and phosphorous concentration, and mineralized matrix formation. …”
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7247
Les conseils consultatifs régionaux : vers une nouvelle gouvernance pour les pêches de l’union européenne ?
Published 2009-11-01“…Since the 70’s, the technological growth and the incredible progress on fishing gears lead the worldwide fleet to overcapacity and overexploitation of almost 75 percent of fish stocks. …”
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Invention, centralité et fin du travail
Published 2020-06-01“…Through its spread and progressive hegemony, this social relationship has become the reference to perceive, think and organize any other activity. …”
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7251
How to Develop Parent-child Family Rehabilitation for Deaf Babies
Published 2015-08-01“…In the whole activity, the four steps of oral hearing method should be followed, including told, demonstration, operation and feedback, and every field goal should be integrated in a game.Results:After the parent-child family rehabilitation, the hand-eye coordination and operation ability of babies got faster progress. The sensitivity, confidence and alarm points of the parents to children were increased. …”
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7254
La définition du parc Matisse dans l’urbanisme d’Euralille
Published 2016-07-01“…The article then analyses the pursuit of the proposed itinerary and the divergences shaped by the successive landscape imaginations : that of Yves Brunier in the conceptual design, and that of Gilles Clément, from the Empreinte Agency, during the progressive formalisation of the project as it is today. …”
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“aaaaaaaaaaaaaaaaaaaaaaaaaambition makes you look [pretty] ugly”: Mass consumption and computer-generated art in Radiohead’s OK Computer
Published 2019-11-01“…It uses paradox in order to assimilate the mass-consumption and technological progress it both abhors and embodies. In an urban landscape of sedated “consumer-robots”, the band embraces the digital era and fuses pop-rock songs with electronic distortion. …”
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Calculer la sémantique avec le langage IEML
Published 2023-12-01“…As far as its applications are concerned, IEML could be the vector of a fluid calculation and communication of meaning – semantic interoperability – capable of decompartmentalising the digital memory and feeding the progress of collective intelligence, artificial intelligence, and digital humanities. …”
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7260
[In]toxic[ating] Bodies: Spirits and Spectral Biopolitics in The House of the Seven Gables
Published 2023-09-01“…From Matthew Maule’s execution to Clifford Pyncheon’s incarceration, Hawthorne deploys the language of intoxication and toxicity to suggest that persons or bodies who do not neatly fit into America’s sense of teleological progress are viewed as infectious, poisonous, noxious, and otherwise threatening.…”
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