Debunking the local government malaise under the decentralization policy in Uganda: an analytical treatise by Julius, Chama

“…A review of the current literature and interviews with stakeholders in local government institutions in Uganda, unveil that conflicts, limited resources and continued fragmentation of districts by politicians have been impediments to progress. Hindrances also included the socio-economic and the political. …”
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Screening and validation of tsRNAs associated with lung adenocarcinoma by LU Chunli, SHAN Yifan, XIE Weijia

“…High expression level of tRF-19-69M8LOJX was associated with shorter progression-free survival （HR=1.565， 95%CI=1.142-2.145， P=0.005）. …”
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From Continent to Ocean: Investigating the Multi-Element and Precious Metal Geochemistry of the Paraná-Etendeka Large Igneous Province Using Machine Learning Tools by J. J. Lindsay, H. S. R. Hughes, C. M. Yeomans, J. C. Ø. Andersen, I. McDonald

“…We conclude that, given the similarities in PGE studies of plume-rift environments, SCLM incorporation under progressively shallowing (i.e., rifting) asthenospheric conditions promotes the acquisition of metasomatic and residual PGE-bearing minerals, boosting the magma metal budget.…”
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Retinoprotective therapy of glaucoma by A.S. Makarova

“…</p> <p> <b>Conclusions</b>: the use of the neuroprotective drug in patients with the progression of primary open-angle glaucoma co-occurring with the changes in systemic hemodynamics enabled to achieve stabilization and improvement of the visual functions. …”
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Patellofemoral Joint Loading During Bodyweight One-Legged and Two-Legged BOSU and Floor Squats by Rafael Escamilla, Naiquan Zheng, Toran D. MacLeod, Rodney Imamura, Kevin E Wilk, Shangcheng Wang, Robert Asuncion, Irwin S. Thompson, Arnel L. Aguinaldo, Glenn S Fleisig

“…Understanding how patellofemoral force and stress magnitudes affects different squat variations will aid clinicians in determining how and when to prescribe and progress these squatting types of exercises in patients with patellofemoral pain…”
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Comparison of the Effects of Mesenchymal Stem Cells with Their Extracellular Vesicles on the Treatment of Kidney Damage Induced by Chronic Renal Artery Stenosis by Crysthiane Saveriano Rubiao Andre Ishiy, Milene Subtil Ormanji, Edgar Maquigussa, Rosemara Silva Ribeiro, Antonio da Silva Novaes, Mirian Aparecida Boim

“…Chronic hypoxia can lead to irreversible damage to renal tissue and to a progressive deterioration of renal function. We have previously shown that bone marrow-derived mesenchymal stem cells (BMSCs) improved renal parenchyma and function in a model of RH (2 kidneys, 1 clip model (2K-1C) in rats. …”
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Family Function and Self-Management of Patients With Early Chronic Kidney Disease: The Mediating Roles of Self-Perceived Burden and Ego Depletion by Cui Y, Liu N, Guo Z, Liu Q, Zhang M, Li J, Mu H, Zhang Y, Chen X

“…The total indirect effect was 0.304 (95% CI: 0.234 to 0.388, P < 0.001), accounting for 56.82% of the total effect (β = 0.535, 95% CI: 0.420 to 0.651, P < 0.001).Conclusion: This study highlights the importance of self-management for patients and their families and provides new important theoretical guidance for multiple interventions of improving family function, reducing self-perceived burden and ego depletion to improve self-management, which is of great value in delaying the progression of renal disease.Keywords: chronic kidney disease, family function, self-management, self-perceived burden, ego depletion…”
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IOP-lowering therapy and ocular surface in glaucoma. Part 1. The effects of drug substances of glaucoma medications on the ocular surface by A.V. Antonova, V.P. Nikolaenko, V.V. Brzheskiy

“…Dose- and exposition-dependent loss of goblet cells, corneal epithelial toxicity, meibomian gland dysfunction, increased activity and expansion of fibroblasts, and pro-inflammatory cytokine release from goblet cells account for the development and progression of symptoms and signs of dry eye as demonstrated by progressive deterioration in Ocular Surface Disease Index (OSDI), Norn’s test, and Schirmer’s test. …”
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Randomised, multicentre, placebo-controlled trial of fenofibrate for treatment of diabetic macular oedema with economic evaluation (FORTE study): study protocol for a randomised co... by Gerald Liew, Paul Mitchell, Bamini Gopinath, Helen Nguyen, Richard Kha

“…Fenofibrate has been shown to reduce the progression of DR. However, there is a lack of high-quality data on the effects of fenofibrate on established DMO. …”
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Autoimmune Hepatitis in Children: The Current State of the Problem by G. V. Volynets, A. I. Khavkin, T. A. Skvortsova, V. V. Matkash

“…Autoimmune hepatitis (AIH) in children has a progressive course with the outcome to liver cirrhosis. …”
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Changes in sarcopenia and incident cardiovascular disease in prospective cohorts by Qingyue Zeng, Lijun Zhao, Qian Zhong, Zhenmei An, Shuangqing Li

“…Compared to participants with stable non-sarcopenia status, those who progressed from non-sarcopenia to possible sarcopenia or sarcopenia exhibited a significantly increased risk of new-onset CVD (HR 1.30, 95% CI 1.06–1.59). …”
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Hydrogen production by water electrolysis: Advances, challenges and future prospects by Zheng ZHANG, Lingjun SONG

“…As science and technology progress, electrolysis technology for hydrogen production will significantly contribute to global carbon neutrality. …”
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Hepatoprotective Effects of a Novel Trihoney against Nonalcoholic Fatty Liver Disease: A Comparative Study with Atorvastatin by Hamad Abdulsalam Hamad Alfarisi, Muhammad Bin Ibrahim, Zenab B. Hamad Mohamed, Nuraniza Azahari, Asmah Hanim Bt. Hamdan, Che Anuar Che Mohamad

“…Trihoney showed histological protection against progression of NAFLD to nonalcoholic steatohepatitis (NASH). …”
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Leukopenia and thrombocytopenia in dengue patients presenting in the emergency department of a tertiary center in Nepal: a cross-sectional study by Bibechan Thapa, Prakriti Lamichhane, Trishna Shrestha, Saral Lamichhane, Shreyasi Karki, Sneha Pradhananga, Kabita Hada Batajoo, Prajwal Pudasaini

“…Leukopenia and thrombocytopenia could indicate progression to severe disease during emergency department admission.…”
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The role of endothelial cell-related gene COL1A1 in prostate cancer diagnosis and immunotherapy: insights from machine learning and single-cell analysis by Gujun Cong, Jingjing Shao, Feng Xiao, Haixia Zhu, Peipei Kang

“…In vitro experimental analysis of the impact of COL1A1 on the progression of PRAD. Results Single-cell analysis identified 12 differential prognostic genes associated with endothelial cells. …”
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Identification and Verification of Novel Biomarkers Involving Rheumatoid Arthritis with Multimachine Learning Algorithms: An In Silicon and In Vivo Study by Fucun Liu, Juelan Ye, Shouli Wang, Yang Li, Yuhang Yang, Jianru Xiao, Aimin Jiang, Xuhua Lu, Yunli Zhu

“…In addition, CRTAM might fuel cancer progression through immune signals, especially among RA patients.…”
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Effect of Graphene Warm Abduction Orthosis on Hip Joint Development in Children with Spastic Cerebral Palsy by CUI Meiyu, LIU Jianjun, ZHANG Yan, ZENG Fanyong

“…The migration percentage (MP), acetabular index (AI), neck shaft angle (NSA), gross motor function measure (GMFM) and modified Tardieu scale (MTS) were measured before and after treatment, and the differences were calculated.ResultsCompared with before treatment (47.67±3.56), the GMFM (49.9±13.08) after treatment in the control group significantly improved (<italic>P</italic>&lt;0.05), and the change of MP, AI and MTS were not significant (<italic>P</italic>&gt;0.05), and NAS (152.20±8.72)° was progressing (154.27±1.03)° (<italic>P</italic>&lt;0.05). …”
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A variant in GRN of Spanish origin presenting with heterogeneous phenotypes by M. Menéndez-González, A. García-Martínez, I. Fernández-Vega, A. Pitiot, V. Álvarez

“…Results: Phenotypes were strikingly different, including cases presenting with behavioral variant frontotemporal dementia, semantic variant primary progressive aphasia, rapidly progressive motor neuron disease (pathologically documented), and tremor-dominant parkinsonism. …”
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Transcranial Doppler sonography follow-up study in mild vascular cognitive impairment. by Mariagiovanna Cantone, Manuela Pennisi, Giuseppe Lanza, Raffaele Ferri, Francesco Fisicaro, Francesco Cappellani, Emanuele David, Vito Nicosia, Klizia Cortese, Giovanni Pennisi, Valentina Puglisi, Rita Bella

“…Here, we perform a clinical, psychopathological, and neurosonological follow-up of patients with VCI in order to monitor any progression and to identify TCD measures to detect it.…”
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Factors That Influence Refractive Changes in the First Year of Myopia Development in Premature Infants by Jianbo Mao, Jimeng Lao, Chenyi Liu, Mingyuan Wu, Xueting Yu, Yirun Shao, Lin Zhu, Yiqi Chen, Lijun Shen

“…Severe ROP was an important contributing factor in myopia progression, which may be related to the treatment required. …”
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