Neratinib and the Role of Anti‐HER2 Therapy in Salivary Duct Carcinoma by Martina Napolitano, Lucia Trudu, Enrica Martinelli, Chiara Santini, Massimo Dominici, Federica Bertolini

“…Case We report the case of a 64‐year‐old female with extra‐ and intracranial metastases of SDC with evidence of AR and HER2 overexpression. After progression on first line chemotherapy, was administered neratinib, a pan‐Erb2 receptor tyrosine kinase inhibitor. …”
Get full text

Intelligent hydraulic fracturing under industry 4.0—a survey and future directions by Jing Jia, Qinghu Fan, Jianglu Jing, Kehui Lei, Lichang Wang

“…The paper reviews technological progress, foresees future benchmarks, and predicts the potential for unmanned fracturing operations, including site reconnaissance, autonomous fracturing unit driving, intelligent wellsite layout, fluid mixing, and operation execution. …”
Get full text

Utility of multimodal imaging in the clinical diagnosis of inherited retinal degenerations by Brian J. H. Lee, Christopher Z. Y. Sun, Charles J. T. Ong, Kanika Jain, Tien-En Tan, Choi Mun Chan, Ranjana S. Mathur, Rachael W. C. Tang, Yasmin Bylstra, Sylvia P. R. Kam, Weng Khong Lim, Beau J. Fenner

“…Clinical phenotyping provides a foundation for understanding disease progression and informing subsequent genetic investigations. …”
Get full text

Sharp Curvature of Premolar Resulting in External Apical Root Resorption of the Neighbouring Molar by Özgür İlke Atasoy Ulusoy

“…One-year followup of the apical external resorption did not show any progression. External apical root resorption affecting single permanent tooth may be induced from the pressure exerted during the eruption of the adjacent tooth with unusual root morphology. …”
Get full text

Vitamin D Deficiency Presenting as Proximal Myopathy: An Overlooked Diagnosis - A Case Series and Review of the Literature by Venkatraman Rajkumar

“…Insidious onset and progressive proximal pelvic girdle myopathy, in the absence of other neurological findings, in the appropriate patient should prompt the physician to test for serum 25 hydroxyvitamin D levels. …”
Get full text

Lipidome disruption in Alzheimer’s disease brain: detection, pathological mechanisms, and therapeutic implications by Sijia He, Ziying Xu, Xianlin Han

“…Finally, we assessed the progresses and obstacles in lipid-based therapeutics and proposed potential strategies for leveraging lipidomics in the treatment of AD.…”
Get full text

Prediction and evaluation of residual life of casing with corrosion defects by JIA Aoyin, QIAN Liqin, WANG Jie, YANG Jingwei, WU Yaokun, WEI Mingji

“…ObjectiveAs oil field development progresses into the middle and later stages, casing damage becomes increasingly severe, particularly incidents such as leakage, reduction in diameter, bending, and fractures caused by corrosion defects, leading to unsafe operations. …”
Get full text

Entre o comércio e a governação local. Fernão Gonçalves Façanha: um mercador eborense de finais da Idade Média by Joaquim Bastos Serra

“…Despite the crisis and the troubles that have marked much of the time in which he lived, Fernão Gonçalves will experience a process of enrichment and social empowerment, which will progressively bring him closer to the leading group. …”
Get full text

High Grade Glioma Mimicking Voltage Gated Potassium Channel Complex Associated Antibody Limbic Encephalitis by Dilan Athauda, R. S. Delamont, E. De Pablo-Fernandez

“…Clinicoradiological progression despite effective immunosuppressive treatment should prompt clinicians to look for alternative diagnoses. …”
Get full text

A Rare Cause of Hemophagocytic Lymphohistiocytosis: Fusobacterium Infection—A Case Report and Review of the Literature by Ghulam Rehman Mohyuddin, Heather J. Male

“…Broad spectrum antibiotics were initiated, and a lumbar puncture ruled out meningitis. Patient progressively developed shock that required use of vasopressors, as well as renal and respiratory failure. …”
Get full text

A Rectal Cancer Surgery Dataset: Use of artificial intelligence to aid automation of error identification by Walaa Ghamrawi, Nathan Curtis, Jialang Xu, Matt Boal, Evangelos Mazomenos, Eddie Edwards, Danail Stoyanov, Nader Francis

“…This dataset can inform machine learning to assist progress toward a fully automated, objective assessment of surgical skills.…”
Get full text

Physical One‐Way Functions for Decentralized Consensus Via Proof of Physical Work by Marvin Winkler, Catharina Peither, Simon Petrick, Lothar Seidemann, Holger Jelich, Frank Kleine Jäger, Jörn Müller‐Quade, Alexander Colsmann, Hermann Nirschl, Frank Rhein

“…This work initiates a progressive, interdisciplinary field of research and demands further investigations with regards to alternative setups, security definitions and strategies for challenging them.…”
Get full text

Networking technology and implementation method based on 5G slice private line by Yan ZHANG

“…With the progressive application of 5G technology in 2B user network, the integration of fixed and mobile collaborative networking and DICT technology is the trend of future development.The establishment of fixed line from 5G network wireless access to 2B user site or cloud system, was analyzed the STN line, OTN line of fixed network, and the 5G network slice defined by 3GPP were used to study and compare the networking characteristics of 5G-STN, 5G-STN into cloud and 5G-OTN of 5G slice line, and the end-to-end specific network capabilities.The fixed-mobile collaborative networking scheme was tested on the operator's network to consolidate and verify 5G slicing private line networking technology, drive the implementation of 5G slicing private line networking technology, and accelerate the integration of “5G+” and the real economy.…”
Get full text

Multiple Giant Liver Cysts in a Nepalese Lad by Ashish Lal Shrestha, Shova Banstola Paudel, Saurav Krishna Malla

“…An 8-year-old previously healthy lad presented to the office with progressive upper abdominal fullness and pain for a year. …”
Get full text

Artificial Intelligence in Pediatric Electrocardiography: A Comprehensive Review by David M. Leone, Donnchadh O’Sullivan, Katia Bravo-Jaimes

“…This review examines the current state of AI-enhanced ECG interpretation in pediatric cardiology applications, drawing insights from adult AI-ECG research given the progress in this field. It describes a broad range of AI methodologies, investigates the unique challenges inherent in pediatric ECG analysis, reviews the current state of the literature in pediatric AI-ECG, and discusses potential future directions for research and clinical practice. …”
Get full text

Oncocytic papillary renal cell carcinoma (OPRCC): 2 case report and literature review by Yanchen Wang, Yanchen Wang, Lihui Guan, Lihui Guan, Yaming Liu, Yuxuan Liu, Xiaoyan Guo, Yaofei Sun, Yaofei Sun

“…The information of these two cases is described as follows, and the literature is further reviewed to share the current diagnosis and treatment characteristics of OPRCC and the research progress after surgery. At the same time, the diagnosis of OPRCC disease is subdivided from PRCC disease, and the diagnosis of OPRCC disease is more precise. …”
Get full text

Mid‐Infrared Optoelectronic Waveguide Devices with 2D Materials by Liqiang Qi, Tianping Xu, Zhengkun Xing, Si Chen, Zunyue Zhang, Tiegen Liu, Zhenzhou Cheng

“…This review summarizes the previous progress, current status, and future trends in exploring mid‐IR optoelectronic waveguide devices with 2D materials. …”
Get full text

Exercise and the Cardiovascular System by Saeid Golbidi, Ismail Laher

“…However, the exact mechanisms by which exercise influences the development and progression of cardiovascular disease are unclear. In this paper we review some important exercise-induced changes in cardiac, vascular, and blood tissues and discuss recent clinical trials related to the benefits of exercise. …”
Get full text

Iron and ferroptosis in kidney disease: molecular and metabolic mechanisms by Wenjie Wang, Jingdi Chen, Liying Zhan, Handong Zou, Lu Wang, Mengmeng Guo, Hang Gao, Jing Xu, Wei Wu

“…Over the past decade, ferroptosis’ role in mediating the development and progression of renal disorders, such as acute kidney injury (renal ischemia-reperfusion injury, drug-induced acute kidney injury, severe acute pancreatitis induced acute kidney injury and sepsis-associated acute kidney injury), chronic kidney disease (diabetic nephropathy, renal fibrosis, autosomal dominant polycystic kidney disease) and renal cell carcinoma, has come into focus. …”
Get full text

Enhancing Canada's sustainable development goals: Leveraging neutrosophic programming for agenda 2030 by Anas Melethil, Nabil Ahmed Khan, Golam Kabir, Ahmad Yusuf Adhami, Irfan Ali

“…The findings indicated substantial progress in GDP and employment, with GDP projections aligning closely with ARIMA forecast values. …”
Get full text