Recent advances in mesenchymal stem cell therapy for multiple sclerosis: clinical applications and challenges by Kamran Sheikhi, Salah Ghaderi, Hassan Firouzi, Sarvenaz Rahimibarghani, Ehsan Shabani, Hamed Afkhami, Hamed Afkhami, Hamed Afkhami, Aref Yarahmadi

“…Current pharmacological treatments primarily target immune modulation but fail to arrest disease progression or entirely reverse CNS damage. Mesenchymal stem cell (MSC) therapy offers a promising alternative, leveraging its immunomodulatory, neuroprotective, and regenerative capabilities. …”
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RECENT ADVANCES IN ENVIRONMENTAL PROTECTION OF OIL POLLUTED SURFACE AND GROUNDWATER IN THE NIGERIAN CONTEXT by Joshua Ighalo, Adewale George Adeniyi, Kevin Shegun Otoikhian

“…The paper has given a clear opinion on the progress of environmental protection and sustainability in the Nigerian context. …”
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Ursodeoxycholic acid in complex treatment of metabolic syndrome by O. A. Tanchenko, S. V. Naryshkina, O. N. Sivyakova

“…Addition of Ursosan to complex treatment of patients with metabolic syndrome results in significant decrease of immunoreactive insulin, atherogenous fractions of lipids parameters with the tendency for decrease of leptin that playing the leading role in development and progression of metabolic syndrome.…”
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Identification of a Novel Primary Atopic Disorder due to STAT6 Gain-of-Function Mutations by Safa Barış, Talal A. Chatila

“…Over the course of the past decades, this area of research has witnessed significant progress in describing numerous monogenic disorders. …”
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Anti-HSV-1 agents: an update by Wenwen Lv, Lei Zhou, Jia Wu, Jishuai Cheng, Yongzhong Duan, Wen Qian

“…The present review provides an update on the progress made over approximately 60 years regarding anti-HSV-1 agents while also highlighting future perspectives for controlling HSV-1 infections.…”
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The Role of Toll-Like Receptor 4 in Infectious and Noninfectious Inflammation by Monica Molteni, Sabrina Gemma, Carlo Rossetti

“…This review focuses on the research progress about the role of TLR4 activation in infectious and noninfectious (e.g., sterile) inflammation and the effects of TLR4 signaling in some pathological conditions.…”
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Overview of the statistics of application and funding of the National Natural Science Foundation of China in 2022 in the area of“information and communication systems” by Ling SUN, Caijun ZHONG, Chenglin LI

“…In order for the broad scientific researchers to know the basic research teams, main research directions and development trends in the area of “information and communication systems” of the National Natural Science Foundation of China, some key statistics regarding the application and funding in the area including the general program, young scientists fund, and fund for less developed regions in 2022 were presented.The information of supporting institutions of the application and funding, as well as the distribution of application codes for the general program and young scientists fund were presented, the two types receiving largest number of applications among various types of projects funded by the National Natural Science Foundation.Then the reform progress in terms of classified proposal review process based on different attributes of scientific problems and the RCC evaluation mechanism was introduced.Finally, the key development directions of the area during the 14th five-year plan period were pointed out.…”
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Advances in allogeneic hematopoietic stem cell transplantation for Langerhans cell histiocytosis in children by Guangqiang Meng, Saran Feng, Yan Wang

“…Although systemic treatments such as chemotherapy and BRAF/MEK inhibitors have improved the cure rate of LCH, disease reactivation rates remain 30%, and eventually some patients progress to relapse-refractory LCH. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a promising salvage treatment strategy for children with relapse-refractory LCH. …”
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MTFAP: a comprehensive platform for predicting and analyzing master transcription factors by Jianyuan Zhou, Haojie Yu, Chunhui Lou, Min Yang, Yanshang Li, Qian Yang, Shuhan Li, Chunwang Ji, Song Li, Shuang Wang, Haotian Cao, Xuecang Li, Lian Liu

“…Compelling evidence reveals a strong correlation between the operation of MTFs and the initiation and progression of cancer. Nevertheless, the challenge of identifying MTFs imposes a barrier for researchers. …”
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Bicuspid Aortic Valve and Thoracic Aortic Aneurysm: Three Patient Populations, Two Disease Phenotypes, and One Shared Genotype by Robert B. Hinton

“…Bicuspid aortic valve (BAV) and thoracic aortic aneurysm (TAA) are two discrete cardiovascular phenotypes characterized by latent progressive disease states. There is a clear association between BAV and TAA; however the nature and extent of this relationship is unclear. …”
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Les communistes espagnols : les années difficiles (1947-1956) by Serge Buj

“…Through documents pertaining to the underground years of the Communist Party of Spain (Partido Comunista de España, pce), particularly reports written in connection with meetings of activists, congresses or conferences, we’ll attempt to understand the image that the pce wanted to project - an image of strength, organization, progress and action. The party’s effort to construct and project an image of itself was motivated by a vital concern: to exist and reinvent itself. …”
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Mining the Prognostic Value of HNRNPAB and Its Function in Breast Carcinoma by Yun Cao, Wei Zhang, Yi-Ting Jin, Qiang Zou

“…Heterogeneous nuclear ribonucleoproteins (HNRNPs) are crucial members in the pathogenesis and progression of numerous cancers. However, the expression pattern and clinical significance of HNRNPs in breast carcinoma (BC) remain to be investigated. …”
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General method to synthesize aggregation‐induced emission molecules via carbon‐sulfur bond activation by Bowei Ma, Xinyu Liang, Gu Xu, Guanghao Zhang, Lutang Zhao, Liangzhuo Ma, Wenbin Xie, Xiang Li, Qinqin Shi, Kaikai Wen, Hui Huang

“…However, the synthetic methods for these olefins remain limited, impeding the progress of AIEgens. This study introduces an unprecedented cross‐coupling reaction between aryl sulfonium triflates and tosylhydrazones from naturally abundant thioethers and ketones. …”
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A stumbling block in pancreatic cancer treatment: drug resistance signaling networks by Jinming Liu, Biao Zhang, Bingqian Huang, Kexin Zhang, Fujia Guo, Zhizhou Wang, Dong Shang, Dong Shang

“…The primary node molecules in the cell signaling network in cancer tissues are maladjusted and mutated in comparison to normal tissues, which promotes the occurrence and progression of cancer. Pancreatic cancer (PC) is a highly fatal cancer with increasing incidence and low five-year survival rates. …”
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New visions for sustainability during a pandemic Towards sustainable wellbeing in a changing planet by Adriana GALVANI, Maria SOTELO PEREZ, Alan LEW

“… Sustainability has been evolving in tandem with societal progress, and as humankind advances, the vision and quality of sustainable development will also change, and most likely in ways that are as yet unpredictable. …”
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Réflexions sur une expérience interdisciplinaire dans le cadre d’une recherche exploratoire by Hélène David, Esther Cloutier, Catherine Teiger, Johanne Prévost

“…It was found that the interdisciplinary approach contributed at the level of research, in the form of general scientific spin-offs and progress in the individual disciplines, and at the level of the workplace, in the form of functional and other spin-offs affecting the dynamics of social change.…”
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Expiratory Flow Limitation Definition, Mechanisms, Methods, and Significance by Claudio Tantucci

“…In any circumstances EFL predisposes to pulmonary dynamic hyperinflation and its unfavorable effects such as increased elastic work of breathing, inspiratory muscles dysfunction, and progressive neuroventilatory dissociation, leading to reduced exercise tolerance, marked breathlessness during effort, and severe chronic dyspnea.…”
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Oxidative Stress, Tumor Microenvironment, and Metabolic Reprogramming: A Diabolic Liaison by Tania Fiaschi, Paola Chiarugi

“…Cancer cells are located in a very complex microenvironment together with stromal components that participate to enhance oxidative stress to promote tumor progression. Indeed, convincing experimental and clinical evidence underline the key role of oxidative stress in several tumor aspects thus affecting several characteristics of cancer cells. …”
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Unusual Cushing’s Syndrome and Hypercalcitoninaemia due to a Small Cell Prostate Carcinoma by Antonio Balestrieri, Elena Magnani, Fiorella Nuzzo

“…Despite medical treatments, Cushing’s syndrome was not controlled and the patient’s clinical condition progressively worsened. Surgical resection was excluded; the patient underwent a cycle of chemotherapy followed by febrile neutropenia and fatal intestinal perforation. …”
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HYDROXYLAPATITE OF BONE TISSUE: DYNAMICS OF CRYSTALLOCHEMICAL ALTERATIONS UPON OSTEOPOROSIS by A.A. Bibko, O.V. Bukharova, E.A. Kostrub, A.G. Miroshnichenko, M.V. Korovkin

“…The X-ray diffraction revealed the increase in the unit cell parameters of hydroxylapatite with the osteoporosis progression. The results of IR spectroscopy showed the presence of a carbonate group in hydroxylapatite, the content of which decreases with disease.…”
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