Assessment of Visual Quality in Eyes with Forme Fruste Keratoconus and Mild and Moderate Keratoconus Based on Optical Quality Analysis System II Parameters by Zhonghao Ren, Liyan Xu, Qi Fan, Kaili Yang, Shengwei Ren, Dongqing Zhao

“…The OQAS-II has the potential value in screening FFK from normal eyes and might be a useful tool for evaluating the progression of keratoconus.…”
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Risk factors and renal outcomes of AKI in children with secondary steroid-resistant nephrotic syndrome by Nannan Yu, XiaoJun Ouyang, Jie Li, Jie Gao, Shuhan Zeng, Hongjie Zhuang, Mengjie Jiang, Yuxin Pei, Xiaoyun Jiang

“…Furthermore, AKI was identified as a risk factor for the progression of secondary SRNS to ESKD.…”
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Oncometabolite D-2HG drives tumor metastasis and protumoral macrophage polarization by targeting FTO/m6A/ANGPTL4/integrin axis in triple-negative breast cancer by Siyue Zhang, Ning Zhang, Tong Wan, Yinqiao He, Jie Hao, Yiwei Liu, Yidong Liu, Bing Chen, Wenjing Zhao, Lijuan Wang, Dan Luo, Chao Gao, Qifeng Yang

“…Conclusions Our study unveils a previously unrecognized role for D-2HG-mediated RNA modification in TNBC progression and targeting the D-2HG/FTO/m6A/ANGPTL4/integrin axis can serve as a promising therapeutic target for TNBC patients.…”
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Polo-like Kinase 1 Expression as a Biomarker in Colorectal Cancer: A Retrospective Two-Center Study by Lana Jajac Brucic, Vesna Bisof, Majana Soce, Marko Skelin, Ivan Krecak, Andjela Nadinic, Branka Vrbicic, Zivana Puljiz, Suzana Hancic, Slavko Gasparov

“…The aim of this study was to assess PLK-1 expression considering the age of the patients and its effects on overall survival (OS) and progression-free survival (PFS). <b>Results</b>: A total of 146 patients with metastatic colorectal cancer (mCRC) were included in this retrospective two-center study. …”
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Symptomatic Pituitary Metastasis as Initial Manifestation of Renal Cell Carcinoma: Case Report and Review of Literature by Gunjan Y. Gandhi, Russell Fung, Patrick E. Natter, Raafat Makary, K. C. Balaji

“…He is presently stable with no radiological evidence of progression or new intracranial disease on subsequent imaging. …”
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Outcomes of Idecabtagene Vicleucel Therapy in Patients with Relapsed/Refractory Multiple Myeloma: A Single-Institution Experience by Aaron Trando, Farid Ghamsari, Philip Yeung, Caitlin Costello, Ila Saunders, Ah-Reum Jeong

“…After a median follow-up of 13 months, median progression-free survival (PFS) was 13.9 months (95% CI: 9.21 months—not reached [NR]); median overall survival (OS) was not reached (95% CI: 19.5 months—NR). …”
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Inflammatory Indices and MAFLD Prevalence in Hypertensive Patients: A Large-Scale Cross-Sectional Analysis from China by Shen D, Cai X, Hu J, Song S, Zhu Q, Ma H, Zhang Y, Ma R, Zhou P, Yang W, Hong J, Zhang D, Li N

“…Metabolic dysfunction-associated fatty liver disease (MAFLD) is also associated with chronic low-grade inflammation, which drives disease progression via metabolic imbalances and adipose tissue dysfunction. …”
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Perspektywiczne kierunki rozwoju biologii człowieka w Polsce, ze szczególnym uwzględnieniem auksologii by Napoleon Wolański, Anna Siniarska

“…If science has been interfered in technique continuously, the technical progress which makes our life easier would have been stopped. …”
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Clinicodemographic profile and predictors of poor outcome in hospitalised COVID-19 patients: a single-centre, retrospective cohort study from India by Prashant K Singh, Lokesh Tiwari, Alok Ranjan, Prakriti Gupta, Prabhat Kumar Singh, Yogesh Kumar, Yankappa N, Amrita Banerjee, C M Singh

“…Progression in disease severity on days 3–5 of admission or days 6–13 of illness onset acts as ‘turning point’ for timely referral or treatment intensification for optimum use of resources.…”
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The Policy and Governance Observatory as a Facilitator of Smart and Evidence-based Governance by Atiye Yousefi, Mahdi Abdolhamid

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Transient Downregulation of Nanog and Oct4 Induced by DETA/NO Exposure in Mouse Embryonic Stem Cells Leads to Mesodermal/Endodermal Lineage Differentiation by Sergio Mora-Castilla, Juan R. Tejedo, Rafael Tapia-Limonchi, Irene Díaz, Ana B. Hitos, Gladys M. Cahuana, Abdelkrim Hmadcha, Franz Martín, Bernat Soria, Francisco J. Bedoya

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Inflammation and Immune Response in COPD: Where Do We Stand? by Nikoletta Rovina, Antonia Koutsoukou, Nikolaos G. Koulouris

“…Increasing evidence indicates that chronic inflammatory and immune responses play key roles in the development and progression of COPD. Recent data provide evidence for a role in the NLRP3 inflammasome in the airway inflammation observed in COPD. …”
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Donors With Previous Malignancy: When Is It Safe to Proceed With Organ Transplantation? by Vitor Turra, Joao Manzi, Sarah Rombach, Simone Zaragoza, Raphaella Ferreira, Giselle Guerra, Kendra Conzen, Trevor Nydam, Alan Livingstone, Rodrigo Vianna, Phillipe Abreu

“…The growing number of organ donors in the United States, from 14,011 in 2012 to 21,374 in 2022, highlights progress in addressing the critical issue of organ shortages. …”
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Exploiting Microwave Imaging Methods for Real-Time Monitoring of Thermal Ablation by Rosa Scapaticci, Gennaro G. Bellizzi, Marta Cavagnaro, Vanni Lopresto, Lorenzo Crocco

“…Recently, such a technique has significantly progressed in the clinical practice. However, its effectiveness would dramatically improve if paired with a noninvasive system for the real-time monitoring of the evolving dimension and shape of the thermally ablated area. …”
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Adjuvant ozone therapy in necrotizing soft tissue infection. Presentation of a case by Isidro Lamote Matos, Jorge Enrique Rodríguez León, Maydelin Pérez Reina, Niuvys Valera Rodríguez

“…<p>Necrotizing soft tissue infections are characterized by extensive and progressive deterioration of surrounding tissues. This work continues the ozone therapy topic as a complementary and therapeutic technique in patients with this type of infections, as well as its approach in Primary Health Care. …”
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A Review of the Detection Methods for Climate Regime Shifts by Qunqun Liu, Shiquan Wan, Bin Gu

“…These detection methods can be roughly divided into five categories based on different types of abrupt changes, namely, abrupt mean value change, abrupt variance change, abrupt frequency change, abrupt probability density change, and the multivariable analysis. The main research progress of abrupt climate change detection methods is reviewed. …”
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Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum for the rheumatologist by Jyoti Ranjan Parida, Saumya Ranjan Tripathy

“…Although many immunosuppressive drugs have been tried in treatment, no treatment has proven beneficial except cyclosporine which has been shown to retard the progression of SJS/TEN. A patient with SJS/TEN as a presenting feature poses two-fold challenge to a rheumatologist as it could be a manifestation of lupus or side effects of a myriad of drugs used by the rheumatologist.…”
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The Role of the PAX8/PPARγ Fusion Oncogene in Thyroid Cancer by Kimberly A. Placzkowski, Honey V. Reddi, Stefan K. G. Grebe, Norman L. Eberhardt, Bryan McIver

“…The recent discovery of the PAX8/PPARγ translocation in follicular thyroid carcinoma has promoted progress in the role of PPARγ as a tumor suppressor and potential therapeutic target. …”
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Diversity of Cellulolytic Microbes and the Biodegradation of Municipal Solid Waste by a Potential Strain by S. P. Gautam, P. S. Bundela, A. K. Pandey, Jamaluddin, M. K. Awasthi, S. Sarsaiya

“…Temperature also stabilized as the composting process progressed in the piles. The high temperature continued until 30 days of decomposition, after which the temperature dropped to 40°C and below during the maturation. …”
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Transverse Myelitis Associated with Cryptococcus neoformans in an Immunocompetent Patient by David B. Villafuerte, Marco F. Passeri, Rayan Qazi, Moulika Baireddy, Fernando L. Sanchez

“…A 44-year-old Hispanic male presented to the hospital with headache, progressive urinary retention, neck and back pain, and right upper and bilateral lower extremity weakness for five days. …”
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