Helicobacter pylori CagA promotes gastric cancer immune escape by upregulating SQLE by Sifan Liu, Nan Zhang, Xu Ji, Shuyue Yang, Zheng Zhao, Peng Li

“…In summary, our findings highlight the crucial role of the CagA-SQLE-PD-L1 axis in gastric cancer progression, suggesting potential therapeutic strategies for targeting CagA-positive gastric cancer.…”
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Modelling of High-Velocity Impact on Woven Carbon Fibre-Reinforced Plastic Laminate by Nenad Djordjevic, Rade Vignjevic, Kevin Hughes, Tom De Vuyst

“…This paper describes a constitutive model for progressive damage in carbon fibre-reinforced composites (CFRPs), developed in the framework of thermodynamics and coupled with a vector equation of state. …”
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Intestinal Barrier, Permeability and Nonspecific Inflammation in Functional Gastrointestinal Disorders by A. L. Kovaleva, E. A. Poluektova, O. S. Shifrin

“…Disruption of intestinal mucosal barrier may be considered a pathogenetic factor of PD and IBS progression.…”
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Physical activity to prevent older adult falls: an Aotearoa New Zealand approach by Lara Vlietstra, Katrina Pōtiki Bryant, Leigh Hale, Margaret Dando, Debra Waters

“…The majority of the exercises are conducted while standing and progress to where the participant stands with feet close together, on one leg, minimises hands assisting with balance, and practice controlled movements of the body’s centre of mass and body awareness. …”
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Diagnostic and Treatment-Related Challenges in Sinonasal Teratocarcinosarcoma: A Report of Three Cases by W. F. Julius Scheurleer, Weibel W. Braunius, Bernard M. Tijink, Luuk M. Janssen, Frank A. Pameijer, Gerben E. Breimer, Ernst J. Smid, Remco de Bree, Lot A. Devriese, Johannes A. Rijken

“…All three patients died due to progression of their disease. Conclusion. Sinonasal teratocarcinosarcoma is characterized by rapid, aggressive local expansion. …”
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Cerebrovascular ageing: how zebrafish can contribute to solving the puzzle by Guy Malkinson, Guy Malkinson, Catarina M. Henriques, Catarina M. Henriques

“…Cerebrovascular ageing is therefore of particular importance as it links circulatory disease to brain functions, cognition, and behavior. Despite major progress in brain research and related technologies, little is known on how the cerebrovascular network changes its properties as ageing proceeds. …”
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HIV and the Gut Microbiota, Partners in Crime: Breaking the Vicious Cycle to Unearth New Therapeutic Targets by Kishanda Vyboh, Mohammad-Ali Jenabian, Vikram Mehraj, Jean-Pierre Routy

“…Microbial translocation and their downstream effects such as increased indolamine 2,3-dioxygenase (IDO) enzyme expression and activity create a self-sustaining feedback loop which enhances HIV disease progression and constitute a vicious cycle of inflammation and immune activation combining viral and bacterial factors. …”
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Experience in Assessing Competencies in Self-Regulted Learning in Blended Learning Environments by S. M. Bakhisheva, G. B. Golub, A. M. Kemeshova, Z. G. Mukhtar, J. S. Kazhiakparova

“…The results of the study allowed us to draw the following conclu-sions: students’ internal resources for regulating their own learning are general competences, which include the following aspects of activity: determining the request for information, extract-ing and primary processing (systematisation) of information, processing information, planning the learning process, evaluating the product and results of learning activities, evaluating and planning their own progression; methods and assessment tools are practice-oriented tasks.…”
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Induction of cell cycle arrest via the p21, p27–cyclin E,A/Cdk2 pathway in SMMC-7721 hepatoma cells by clioquinol by Huang Zhiwei, Wang Lianqiu, Chen Lifeng, Zhang Yifei, Shi Ping

“…The results demonstrated for the first time that clioquinol suppressed cell cycle progression in the S-phase in SMMC-7721 cells via the p21, p27-cyclin E,A/Cdk2 pathway. …”
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Intricacies of human–AI interaction in dynamic decision-making for precision oncology by Dipesh Niraula, Kyle C. Cuneo, Ivo D. Dinov, Brian D. Gonzalez, Jamalina B. Jamaluddin, Jionghua Judy Jin, Yi Luo, Martha M. Matuszak, Randall K. Ten Haken, Alex K. Bryant, Thomas J. Dilling, Michael P. Dykstra, Jessica M. Frakes, Casey L. Liveringhouse, Sean R. Miller, Matthew N. Mills, Russell F. Palm, Samuel N. Regan, Anupam Rishi, Javier F. Torres-Roca, Hsiang-Hsuan Michael Yu, Issam El Naqa

“…Abstract AI decision support systems can assist clinicians in planning adaptive treatment strategies that can dynamically react to individuals’ cancer progression for effective personalized care. However, AI’s imperfections can lead to suboptimal therapeutics if clinicians over or under rely on AI. …”
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Blood Pressure Control at Rest and during Exercise in Obese Children and Adults by Konstantina Dipla, George P. Nassis, Ioannis S. Vrabas

“…Understanding the mechanisms that drive the altered hemodynamic responses during exercise in obese individuals and prevent the progression to hypertension is vitally important. This paper focuses on the evidence linking obesity with alterations of the autonomic nervous system and discusses the potential mechanisms and consequences of the altered sympathetic nervous system behavior in obese individuals at rest and during exercise. …”
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How does the mode of evolutionary divergence affect reproductive isolation? by De Sanctis, Bianca, Schneemann, Hilde, Welch, John J.

“…In this way, the mode of evolutionary divergence between populations may have predictable consequences for the fitness of their hybrids, and so for the progress of speciation. To investigate these connections, we present a new analysis of hybridization under Fisher's geometric model, making few assumptions about the allelic effects that differentiate the hybridizing populations. …”
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Internal situation in USSR in Russian emigration press in the United States (1964–1982) by T. S. Kulepanova

“…Significant components of image of the USSR were ideas about the Russian people and Soviet youth, which were perceived as progressive forces capable of creating Russia of Future. …”
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Angiotensin Converting Enzyme 2, Angiotensin-(1-7), and Receptor Mas Axis in the Kidney by Sergio Veloso Brant Pinheiro, Ana Cristina Simões e Silva

“…Besides Angiotensin (Ang) II, the biological importance of other Ang fragments was progressively evidenced. In this regard, Angiotensin- (Ang-) (1-7) was recognized as a biologically active product of the RAS cascade with a specific receptor, the G-protein-coupled receptor Mas, and that is mainly formed by the action of the angiotensin-converting enzyme (ACE) homolog enzyme, ACE2, which converts Ang II into Ang-(1-7). …”
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Graph Knowledge Structure for Attentional Knowledge Tracing With Self-Supervised Learning by Zhaohui Liu, Sainan Liu, Weifeng Gu

“…KT assesses students’ learning progress by analysing their historical performance in related exercises. …”
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Extramedullary Plasmacytoma of the Larynx Treated by a Surgical Endoscopic Approach and Radiotherapy by Massimiliano Pino, Filippo Farri, Pietro Garofalo, Fausto Taranto, Andrea Toso, Paolo Aluffi

“…Herein we report an uncommon case of EMP of the larynx in a 65-year-old male who presented with a history of progressive dysphonia and hoarseness. Laryngeal fiberscopy evidenced a reddish pedicled voluminous mass in the left false cords and ventricle. …”
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Monitoring the follow-up of autoimmune chronic atrophic gastritis using parietal cell antibodies and markers of gastric function by Maria Piera Panozzo, Antonio Antico, Nicola Bizzaro

“…This integrated approach will allow for the more effective real-time monitoring of the state of the gastric mucosa. As A-CAG is a progressive disorder associated with an increased risk of gastric cancer and neuroendocrine tumors, the precise follow-up of patients with gastric atrophy needs to be better defined. …”
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Tram-Oriented Traffic Signal Timing Resynchronization by Yuxiong Ji, Yu Tang, Wei Wang, Yuchuan Du

“…The model depicts both tram and vehicle progressions in one signal timing plan, making it possible to control the impact of signal timing resynchronization through traffic. …”
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T Cell Activation and Regulation of HIV-1: Same Effectors with Distinct Outcomes by Jean-François Fortin, Benoit Barbeau, Gilles A Robichaud, Michel J Tremblay

“…A better understanding of the regulation of HIV-1 gene expression is of utmost importance for the design of molecular approaches that will effectively abrogate virus replication and, ultimately, disease progression.…”
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A Comprehensive Dataset on Microbiome Dynamics in Rheumatoid Arthritis from a Large-Scale Cohort Study by Jing Li, Jun Xu, Jiayang Jin, Congmin Xu, Yuzhou Gan, Yifan Wang, Ruiling Feng, Wenqiang Fan, Yingni Li, Xiaozhen Zhao, Yucui Li, Shushi Gong, Linchong Su, Yueming Cai, Lianjie Shi, Xiaolin Sun, Yang Xiang, Qingwen Wang, Ru Li, Jinxia Zhao, Yulan Liu, Junjie Qin, Zhanguo Li, Jing He

“…By integrating 16S rRNA gene sequencing with demographic, clinical, and environmental data, we offer a valuable resource to explore the complex relationships between gut microbiota and RA progression. This large-scale dataset is expected to be a foundation for collaborative research, advancing our understanding of the microbiome’s systemic effects in RA and other autoimmune diseases and potentially guiding new therapeutic approaches.…”
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