Liver Transplantation and Hepatitis C by Nobuhisa Akamatsu, Yasuhiko Sugawara

“…Although immunosuppressive regimens have a considerable impact on the outcome, the optimal regimen after liver transplantation for HCV-infected patients remains unclear. Disease progression monitoring with protocol biopsy and new noninvasive methods is essential for predicting patient/graft outcome and starting antiviral treatment with the appropriate timing. …”
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Optimization of bonding parameters in diffusion bonding of Cu10Sn-B4C composites produced by P/M method by Ada Hakan, Özsoy Serkan

“…At the end of the verification experiments, it was observed that the resistance value obtained in the experimental studies and the estimated value were negligible at 3.71%, and there was a 21.92% progress in shear strength compared to the initial parameter value.…”
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Unilateral Pedicle Stress Fracture in a Long-Term Hemodialysis Patient with Isthmic Spondylolisthesis by Keishi Maruo, Toshiya Tachibana, Shinichi Inoue, Fumihiro Arizumi, Shinichi Yoshiya

“…Computed tomography revealed unilateral pedicle fracture with bilateral L5 spondylolysis and spondylolisthesis with progression of scoliosis. The patient underwent Gill laminectomy of L5 with pedicle screw fixation at L4-S1 and interbody fusion at L5-S1. …”
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Headache in a Child with Pseudohypoparathyroidism: An Alarming Symptom Not to Miss by Sarah Wing-yiu Poon, Brian Hon-yin Chung, Anita Man-ching Tsang, Grace Wing-kit Poon

“…She later developed progressive worsening headache, increased irritability, and vomiting. …”
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Giant Congenital Melanocytic Nevi and Neurocutaneous Melanosis by Catarina Araújo, Cristina Resende, Francisco Pardal, Celeste Brito

“…She followed a rapidly progressive course, reflecting widespread leptomeningeal infiltration, and she died of multiorgan failure seven months after diagnosis of cerebral melanoma. …”
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The Dynamics of Rotor with Rubbing by Jerzy T. Sawicki, Joe Padovan, Rabih Al-Khatib

“…In particular, starting with 2nd order sub/superharmonics, which are symptomatic of quadratic nonlinearity, progressively higher order polynomial behavior is excited, i.e., cubic, giving rise to 3rd order sub/superharmonics. …”
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Elevated expression of ANTXR1 gene in tumors is a poor prognostic biomarker for patients with bladder cancer by L. S. Franco, S. Arunachalam, A. Chauhan, S. A. Kareff, P. L. Hallenbeck

“…Here, we demonstrate that elevated expression of ANTXR1 in bladder cancer showed a statistical difference not only in overall survival (OS) but in progression-free survival (PFS), confirming the prognostic biomarker power of ANTXR1 expression.…”
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Ferroptosis: A New Pathway in the Interaction between Gut Microbiota and Multiple Sclerosis by Junjie Jian, Jun Wei

“…Through an integrated examination of mechanistic pathways and clinical evidence, we discuss how targeting these interactions could lead to novel interventions that not only modulate disease progression but also offer personalized treatment strategies based on gut microbiota profiling. …”
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Positively charged specificity site in cyclin B1 is essential for mitotic fidelity by Christian Heinzle, Anna Höfler, Jun Yu, Peter Heid, Nora Kremer, Rebecca Schunk, Florian Stengel, Tanja Bange, Andreas Boland, Thomas U. Mayer

“…Abstract Phosphorylation of substrates by cyclin-dependent kinases (CDKs) is the driving force of cell cycle progression. Several CDK-activating cyclins are involved, yet how they contribute to substrate specificity is still poorly understood. …”
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Radiation-Induced Peripheral Malignant Nerve Sheath Tumor Arising from Vestibular Schwannoma after Linac-Based Stereotactic Radiation Therapy: A Case Report and Review of Literatur... by Putipun Puataweepong, Taweesak Janwityanujit, Noppadol Larbcharoensub, Mantana Dhanachai

“…At 6 years after SRT, the patient came with left facial palsy and severe headache. CT brain revealed progression in size with cystic and hemorrhagic changes of the preexisting tumor at left CPA with new obstructive hydrocephalus. …”
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Emerging technologies of single-cell multi-omics by Yi June Kim, Koichi Takahashi

“…These technologies have uncovered the intricate landscape of genetic clonality and transcriptional heterogeneity in both normal and malignant hematopoietic systems, highlighting their roles in differentiation, disease progression, and therapy resistance. This review aims to provide a brief overview of the principles of single-cell technologies, their historical development, and a subset of ever-expanding multi-omics tools, emphasizing the specific research questions that inspired their creation. …”
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Emergency Splenectomy in a patient with primary immune thrombocytopenia and hemoperitoneum by Liermis Michael Dita Salabert, José Eduardo Consuegra Díaz, Carlos Jaime Geroy

“…An early clamping of the splenic artery, evacuation of the hemoperitoneum, left adnexectomy, splenectomy and resection of accessory spleen were performed. The patient progressed satisfactorily.…”
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Interactions between Cytokines, Congenital Anomalies of Kidney and Urinary Tract and Chronic Kidney Disease by Ana Cristina Simões e Silva, Flávia Cordeiro Valério, Mariana Affonso Vasconcelos, Débora Marques Miranda, Eduardo Araújo Oliveira

“…In this regard, recent studies suggest a role for cytokines and chemokines in the pathophysiology of CAKUT and for the progression to CKD. Some authors proposed that the evaluation of these inflammatory mediators might help the management of postnatal uropathies and the detection of patients with high risk to developed chronic kidney disease. …”
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Single Posthepatic Portosystemic Shunt Communicated With Internal Thoracic Vein and Azygos Continuation of the Caudal Vena Cava in a Dog by Ryo Takeuchi, Kumiko Ishigaki, Orie Yoshida, Tatsuya Heishima, Kaito Iida, Kazushi Asano

“…Surgical treatment in this case resulted in favourable progress, similar to that in dogs with commonly observed extrahepatic PSS.…”
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Convective Heat Transport in Bidirectional Water Driven Hybrid Nanofluid Using Blade Shaped Cadmium Telluride and Graphite Nanoparticles under Electromagnetohydrodynamics Process by Iftikhar Ahmad, Qazi Zan-Ul-Abadin, Muhammad Faisal, K. Loganathan, Tariq Javed, Ngawang Namgyel

“…The recent progress in nanotechnology provides the concept of hybrid-class nano-fluids having advanced thermal features comparing to regular nanofluids. …”
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Voltage Control of Exchange Bias via Magneto-Ionic Approaches by Yifu Luo, Shengsheng Liu, Yuxin Li, Zhen Wang, Jie Zhang, Limei Zheng

“…This review systematically synthesizes the research progress on voltage control of exchange bias based on the magneto-ionic mechanism from the perspectives of ionic species, material systems, underlying mechanisms, and performance parameters. …”
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Cdk6’s functions are critically regulated by its unique C-terminus by Alessia Schirripa, Helge Schöppe, Sofie Nebenfuehr, Markus Zojer, Thorsten Klampfl, Valentina Kugler, Belinda S. Maw, Huriye Ceylan, Iris Z. Uras, Lisa Scheiblecker, Elisabeth Gamper, Ulrich Stelzl, Eduard Stefan, Teresa Kaserer, Veronika Sexl, Karoline Kollmann

“…C-terminally truncated Cdk6 (Cdk6 ΔC) shows reduced nuclear translocation and therefore chromatin interaction and fails to enhance proliferation and disease progression. The combination of proteomic analysis and protein modeling highlights that Cdk6’s C-terminus is essential for protein flexibility and for its binding potential to cyclin D, p27Kip1 and INK4 proteins but not cyclin B. …”
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Implication of protein post translational modifications in gastric cancer by Houji Song, Mingze Zhang, Chengwang Guo, Xi Guo, Yuqi Ma, Yuntao Ma, Yuntao Ma

“…This review provides a comprehensive overview of the impact of PTM on the occurrence and progression of GC. Specifically, aberrant PTM have been shown to alter the proliferation, migration, and invasion capabilities of GC cells. …”
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A proposed conceptual model for orphan drug market entry by Nataša Jalen, Tina Vukasović

“…They are often chronic, progressive, life-threatening health conditions. Some of them can be treated with medicines called orphan drugs. …”
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Lipopolysaccharide Increases Immune Activation and Alters T Cell Homeostasis in SHIVB’WHU Chronically Infected Chinese Rhesus Macaque by Gao-Hong Zhang, Run-Dong Wu, Hong-Yi Zheng, Xiao-Liang Zhang, Ming-Xu Zhang, Ren-Rong Tian, Guang-Ming Liu, Wei Pang, Yong-Tang Zheng

“…Immune activation plays a significant role in the disease progression of HIV. Microbial products, especially bacterial lipopolysaccharide (LPS), contribute to immune activation. …”
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