COVID-19 and Neutrophils: The Relationship between Hyperinflammation and Neutrophil Extracellular Traps by Leandro Borges, Tania Cristina Pithon-Curi, Rui Curi, Elaine Hatanaka

“…Coronavirus disease 2019 (COVID-19) is a virus-induced respiratory disease that may progress to acute respiratory distress syndrome (ARDS) and is triggered by immunopathological mechanisms that cause excessive inflammation and leukocyte dysfunction. …”
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Designing an effective educational toy: incorporating design-thinking in the design classroom by Natalie Houston, Ferney Manrique, Shi Mo, Wang Ruoqian, Ji Wenjing, Lu Yuting

“…Utilising the ‘Double Diamond Model of Design’, the research methodically progresses through the stages of observation, generation, prototyping, and testing to create a 3D letter-building set with the goal of improving children's educational experiences. …”
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Asymptomatic Barrett’s Oesophagus-Complicated Gastroesophageal Reflux Disease at Ineffective Antisecretory Therapy by E. V. Barkalova, S. S. Pirogov, D. N. Andreev, M. A. Ovsepyan, I. V. Maev, A. D. Kaprin

“…The main challenge to prevent progression into oesophageal adenocarcinoma is an adequate personalised patient management leveraging the modern diagnostic techniques, control of antisecretory treatment and its correction a situ.…”
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The Pathogenesis of Necroptosis-Dependent Signaling Pathway in Cerebral Ischemic Disease by Yang Xu, Ji Zhang, Lingsong Ma, Shoucai Zhao, Shizun Li, Tingting Huang, Zhaohu Chu

“…In this review, we highlight recent progress in the study of roles for necroptosis in cerebral ischemic disease and discuss how these modifications delicately control necroptosis.…”
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The role of myocardial energy metabolism perturbations in diabetic cardiomyopathy: from the perspective of novel protein post-translational modifications by Dongze Li, Li Zhang, Qiming Gong, Huilan Deng, Changfang Luo, Tingting Zhou, Wei Huang, Yong Xu

“…Myocardial energy metabolism disturbances in DbCM, encompassing glucose, fatty acid, ketone body and lactate metabolism, are crucial factors that contribute to the progression of DbCM. In recent years, novel protein post-translational modifications (PTMs) such as lactylation, β-hydroxybutyrylation, and succinylation have been demonstrated to be intimately associated with the myocardial energy metabolism process, and in conjunction with acetylation, they participate in the regulation of protein activity and gene expression activity in cardiomyocytes. …”
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A Perspective on Withania somnifera Modulating Antitumor Immunity in Targeting Prostate Cancer by Seema Dubey, Manohar Singh, Ariel Nelson, Dev Karan

“…The role of WFA is appreciated to polarize tumor-suppressive Th1-type immune response inducing natural killer cell activity and may provide an opportunity to manipulate the tumor microenvironment at an early stage to inhibit tumor progression. This article signifies the cumulative information about the role of WFA in modulating antitumor immunity and its potential in targeting prostate cancer.…”
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Varicella Zoster Meningitis, Optic Neuritis Preceding the Development of Posterior Outer Retinal Necrosis, and Central Retinal Artery Occlusion in a HIV Patient by Manasa Gunturu, Shiva Kumar Gosi, Swetha Kanduri, Vishnu Garla

“…Funduscopic examination showed patchy areas of necrosis in the periphery which were rapidly progressive, diagnostic of posterior outer retinal necrosis (PORN). …”
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Trachoma and Ocular Chlamydial Infection in the Era of Genomics by Tamsyn Derrick, Chrissy h. Roberts, Anna R. Last, Sarah E. Burr, Martin J. Holland

“…The mechanisms driving the chronic immunopathology in the conjunctiva, which largely progresses in the absence of detectable Ct infection in adults, are likely to be multifactorial. …”
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A Case of Non-Small Cell Lung Cancer with Possible “Disease Flare” on Nivolumab Treatment by Shotaro Chubachi, Hiroyuki Yasuda, Hidehiro Irie, Koichi Fukunaga, Katsuhiko Naoki, Kenzo Soejima, Tomoko Betsuyaku

“…Six weeks later, after 3 cycles of nivolumab treatment, rapid lung cancer progression was observed with an increase in the size of the primary lesion, multiple novel nodules on both lungs, and multiple novel brain metastases. …”
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Weight-Loss Cognitive-Behavioural Treatment and Essential Amino Acid Supplementation in a Patient with Spinal Muscular Atrophy and Obesity by Marwan El Ghoch, Paola Vittoria Bazzani, Simona Calugi, Riccardo Dalle Grave

“…Spinal muscular atrophy is a genetic neuromuscular disease characterised by muscle atrophy, hypotonia, weakness, and progressive paralysis. Usually, these patients display increased fat mass deposition and reductions in fat-free mass and resting energy expenditure—an unfavourable condition that facilitates the development of obesity. …”
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Acute Respiratory Distress Syndrome Caused by Influenza B Virus Infection in a Patient with Diffuse Large B-Cell Lymphoma by Silvio A. Ñamendys-Silva, María O. González-Herrera, Julia Texcocano-Becerra, Angel Herrera-Gómez

“…This paper emphasizes the need to suspect influenza B virus infection in critically ill immunocompromised patients with progressive deterioration of cardiopulmonary function despite treatment with antibiotics. …”
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Feasibility, Safety, and Compliance in a Randomized Controlled Trial of Physical Therapy for Parkinson's Disease by Jennifer L. McGinley, Clarissa Martin, Frances E. Huxham, Hylton B. Menz, Mary Danoudis, Anna T. Murphy, Jennifer J. Watts, Robert Iansek, Meg E. Morris

“…Ambulant participants with Parkinson's disease (PD) (n=210) were randomized into three groups: (1) progressive strength training (PST); (2) movement strategy training (MST); or (3) control (“life skills”). …”
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Effect of Soil Burial on Tensile Properties of Polypropylene/Plasticized Cassava Starch Blends by Henry C. Obasi, Isaac O. Igwe, Innocent C. Madufor

“…However, the tensile properties for both PP/PCS and PP/PCS/PP-g-Ma decrease with increases in starch loading and also as the burial period progressed.…”
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Stretchable and body conformable electronics for emerging wearable therapies by Benzhao Huang, Qian Wang, Wei Li, Desheng Kong

“…This review comprehensively overviews recent progress in stretchable and body‐conformable electronics for wearable therapeutic applications. …”
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Mechanisms and therapeutic potential of the hedgehog signaling pathway in cancer by Ge Cong, Xingyu Zhu, Xin Ru Chen, Hao Chen, Wei Chong

“…Extensive research has delineated that the aberrant activity of the hedgehog signaling pathway, whether autocrine or paracrine, is implicated in the initiation and progression of various neoplasms, including medulloblastoma (MB), basal cell carcinoma (BCC) and so on. …”
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Pituitary Adenoma and Hyperprolactinemia Accompanied by Idiopathic Granulomatous Mastitis by Sebahattin Destek, Vahit Onur Gul, Serkan Ahioglu, Kursat Rahmi Serin

“…In order to monitor any progression during the three months of treatment, hormone levels were routinely examined. …”
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Imaging cell spheroid clusters: An MRI protocol for non-invasive standardized characterization by Rebecca Wißmann, Petros Martirosian, Marina Danalache, Gerd Grözinger, Fritz Schick, Stefanie Elser

“…Over the past decade, significant progress has been made in the utilization of three-dimensional cell cultures in the form of spheroids as a bridge between in vitro and in vivo models. …”
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Esophageal Intramural Pseudodiverticulosis: A Rare Endoscopic Finding by Luciana Lopes de Oliveira, Fred Olavo Aragão Andrade Carneiro, Elisa Ryoka Baba, Thiago Guimarães Vilaça, Dalton Marques Chaves, Everson Luiz de Almeida Artifon, Eduardo Guimarães Hourneaux de Moura, Paulo Sakai

“…A 76-year-old woman, presenting with a 4-year history of progressive dysphagia, was submitted to endoscopic examination. …”
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Advanced technologies in InGaN micro-LED fabrication to mitigate the sidewall effect by Zhiyuan Liu, Haicheng Cao, Xiao Tang, Tingang Liu, Yi Lu, Zixian Jiang, Na Xiao, Xiaohang Li

“…Subsequently, we systematically review recent progress in micro-LED fabrication aiming at suppressing sidewall effects. …”
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Hierarchical Structures from Inorganic Nanocrystal Self-Assembly for Photoenergy Utilization by Yun-Pei Zhu, Tie-Zhen Ren, Tian-Yi Ma, Zhong-Yong Yuan

“…In this paper, the recent research progress in this field is reviewed. The general strategies for the synthesis of hierarchical structures assembled from nanobuilding blocks are elaborated. …”
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