The Role of Purinergic Receptors in Cancer-Induced Bone Pain by Sarah Falk, Maria Uldall, Anne-Marie Heegaard

“…The recent development of specific animal models has increased the understanding of the molecular and cellular mechanisms underlying cancer-induced bone pain including the involvement of ATP and the purinergic receptors in the progression of the pain state. In nociception, ATP acts as an extracellular messenger to transmit sensory information both at the peripheral site of tissue damage and in the spinal cord. …”
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Rare forms of nonalcoholic fatty liver disease: hereditary lysosomal acid lipase deficiency by M. V. Mayevskaya, V. T. Ivashkin, M. S. Zharkova, T. P. Nekrasova, G. I. Ayusheva, R. V. Maslennikov

“…There are two forms of DLAL clinical manifestations: as fulminant lethal Wolman disease and slowly progressing cholesterol ethers storage disease (CESD). …”
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The Role of Bridging Therapy in Hepatocellular Carcinoma by Roberto Galuppo, Angie McCall, Roberto Gedaly

“…Shortage of organ donors has resulted in overall increase of waiting list time with increased risk of dropout due to tumor progression. Neoadjuvant therapies have emerged as an alternative to control tumor growth in patients while waiting. …”
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Quality and shelf-life extension of vegetables using precision control storage system by Kok Chai Ling, Chew Boon Kee, Chan Yi Chuen, Ong Mei Kying, Toh Pek Lan, Teoh Shen Khang, Goh Hock Guan

“…For the total soluble solid, the content for all treatments were significantly increased when the storage period progressed. T1 is the most recommended treatment as it had extended one week of storage period and able to retain better sweet taste and appearance compared to the other treatments.…”
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Ultrasound-assisted extraction and value of active substances in Muxu by Huilin Wang, Laiqing Deng, Gangliang Huang

“…This article reviews the latest research progress on ultrasound-assisted extraction of active substances from Muxu, including polysaccharides, polyphenols, leaf proteins, anthocyanins, total flavonoids, and total saponins, in order to provide theoretical references for the extraction of active substances from Muxu. …”
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Management of Cucurbit Downy Mildew in Florida by Mason J. Newark, Matthews L. Paret, Nicholas S. Dufault, Pamela D. Roberts, Shouan Zhang, Gary E. Vallad, Joshua H. Freeman, Eugene McAvoy

“…The classic sign of the disease is the presence of dark sporangia, a structure that holds developing spores, on the underside of infected leaves. As the disease progresses, it may lead to large necrotic areas that cause defoliation and a reduction of yield and marketable fruit. …”
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Analysis of the implications of digital voting through neutrosophic Delphi modeling by Diego Pablo Palma Rivera, Silvio Amable Machuca Vivar, Bolívar Enrique Villalta Jadan, Misael Abisai Valarezo Bracho

“…The modernization of electoral systems through digital technologies, such as electronic voting, has marked significant progress in emerging regions like Santo Domingo de los Tsáchilas, Ecuador. …”
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T Cell Costimulatory Molecules in Anti-Viral Immunity: Potential Role in Immunotherapeutic Vaccines by Tania H Watts, Edward M Bertram, Jacob Bukczynski, Tao Wen

“…By providing antigens and costimulatory molecules together, investigators may be able to increase and broaden the immune response, resulting in better immunological control or even elimination of the infection. Recent progress in understanding the function of costimulatory molecules suggests that different costimulatory molecules are involved in initial immune responses than are involved in recall responses. …”
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Could Metabolic Syndrome, Lipodystrophy, and Aging Be Mesenchymal Stem Cell Exhaustion Syndromes? by Eduardo Mansilla, Vanina Díaz Aquino, Daniel Zambón, Gustavo Horacio Marin, Karina Mártire, Gustavo Roque, Thomas Ichim, Neil H. Riordan, Amit Patel, Flavio Sturla, Gustavo Larsen, Rubén Spretz, Luis Núñez, Carlos Soratti, Ricardo Ibar, Michiel van Leeuwen, José María Tau, Hugo Drago, Alberto Maceira

“…All these clinical situations could be the consequence of a progressive and persistent stem cell exhaustion syndrome (SCES). …”
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Utilizing Language Technology in the Documentation of Endangered Uralic Languages by Ciprian Gerstenberger, Niko Partanen, Michael Rießler, Joshua Wilbur

“… The paper describes work-in-progress by the Pite Saami, Kola Saami and Izhva Komi language documentation projects, all of which record new spoken language data, digitize available recordings and annotate these multimedia data in order to provide comprehensive language corpora as databases for future research on and for endangered – and under-described – Uralic speech communities. …”
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Telomeres, telomerase, and cancer: mechanisms, biomarkers, and therapeutics by Songting Shou, Ayidana Maolan, Di Zhang, Xiaochen Jiang, Fudong Liu, Yi Li, Xiyuan Zhang, En Geer, Zhenqing Pu, Baojin Hua, Qiujun Guo, Xing Zhang, Bo Pang

“…Abstract Telomeres and telomerase play crucial roles in the initiation and progression of cancer. As biomarkers, they aid in distinguishing benign from malignant tissues. …”
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Innovative Drug Modalities for the Treatment of Advanced Prostate Cancer by Maurizio Capuozzo, Mariachiara Santorsola, Monica Ianniello, Francesco Ferrara, Andrea Zovi, Nadia Petrillo, Rosa Castiello, Maria Rosaria Fantuz, Alessandro Ottaiano, Giovanni Savarese

“…This underscores the need to explore innovative treatment strategies for effectively managing prostate cancer progression. Ongoing research endeavors persist in unraveling the complexity of prostate cancer and fostering the development of biologic and innovative approaches, including immunotherapies and targeted therapies. …”
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Application of BIM and 3D Laser Scanning for Quantity Management in Construction Projects by Thu Anh Nguyen, Phong Thanh Nguyen, Sy Tien Do

“…Construction companies consider the measurement of work progress, which often wastes time and has a low resolution, to be one of the most challenging problems faced by project management. …”
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Directed Energy Deposition via Artificial Intelligence-Enabled Approaches by Utkarsh Chadha, Senthil Kumaran Selvaraj, Aakrit Sharma Lamsal, Yashwanth Maddini, Abhishek Krishna Ravinuthala, Bhawana Choudhary, Anirudh Mishra, Deepesh Padala, Shashank M, Vedang Lahoti, Addisalem Adefris, Dhanalakshmi S

“…This review extensively follows all the research work and the contemporary signs of progress in the directed energy deposition (DED) process. …”
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Development of Bullous Disease during Treatment of Pulmonary Marginal Zone B-Cell Lymphoma by S. Ansari, H. Dubaybo, E. Levi, B. A. Dubaybo

“…During the ensuing 4 years, and while on chemotherapy for the MALT lymphoma, sequential CT and pulmonary function tests revealed the development of progressive bullous disease resulting in the replacement of large portions of the lung parenchyma with bilateral bullae. …”
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A review of optical gas sensing technology for dissolved gas analysis in transformer oil by Jialiang Dai, Jialiang Dai, Bing Luo, Xiaowen Shen, Xiaowen Shen, Wenfei Han, Wenfei Han, Ruyue Cui, Ruyue Cui, Jintao Wu, Jintao Wu, Haofeng Zhang, Wei Xiao, Zheng Zhong, Lei Dong, Lei Dong, Hongpeng Wu, Hongpeng Wu

“…This paper reviews the commonly used sensing technologies for analyzing dissolved gases in transformer oil, including Raman spectroscopy (RS), fourier transform infrared spectroscopy (FTIR), tunable diode laser absorption spectroscopy (TDLAS) and photoacoustic spectroscopy (PAS). The progress of research on these four gas sensing technologies is reviewed, with a detailed analysis of their respective principles and characteristics. …”
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Focal Therapy for Prostate Cancer: Recent Advances and Insights by Francesco Lasorsa, Arianna Biasatti, Angelo Orsini, Gabriele Bignante, Gabriana M. Farah, Savio Domenico Pandolfo, Luca Lambertini, Deepika Reddy, Rocco Damiano, Pasquale Ditonno, Giuseppe Lucarelli, Riccardo Autorino, Srinivas Vourganti

“…Focal therapy has emerged as a balanced middle ground aiming to reduce overtreatment and the risk of progression, as well as patients’ distress and anxiety. …”
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Acute Hydrocephalus due to Secondary Leptomeningeal Dissemination of an Anaplastic Oligodendroglioma by Andreas M. Stark, Heinz-Herrmann Hugo, H. Maximilian Mehdorn, Friederike Knerlich-Lukoschus

“…MRI now ruled out local tumor progression but revealed meningeal contrast enhancement along the medulla, the myelon, and the cauda equina. …”
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Combining Convolutional Neural Network (CNN) and Grad-CAM for Parkinson’s Disease Prediction and Visual Explanation by Reyhaneh Dehghan, Marjan Naderan, Seyed Enayatallah Alavi

“…Early detection of Parkinson's disease is an important factor in slowing the progression of the disease. In this study, a Convolutional Neural Network (CNN) namely ConvNet, is used to discriminate Parkinson's patients based on Single Photon Emission Computed Tomography (SPECT) images acquired from the PPMI database. …”
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miR-16-1 Promotes the Aberrant α-Synuclein Accumulation in Parkinson Disease via Targeting Heat Shock Protein 70 by Zhelin Zhang, Yan Cheng

“…There is striking evidence that heat shock protein 70 (Hsp70) negatively regulates α-synuclein aggregation, which plays a significant role in the formation and progression of Parkinson disease (PD). However, how the Hsp70 in neurons fails to prevent or even reverse α-synuclein aggregation and toxicity in PD still remains to be determined. …”
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