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4541
Altered Gene Expression, Mitochondrial Damage and Oxidative Stress: Converging Routes in Motor Neuron Degeneration
Published 2012-01-01“…Motor neuron diseases (MNDs) are a rather heterogeneous group of diseases, with either sporadic or genetic origin or both, all characterized by the progressive degeneration of motor neurons. At the cellular level, MNDs share features such as protein misfolding and aggregation, mitochondrial damage and energy deficit, and excitotoxicity and calcium mishandling. …”
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4542
The Natural History and Treatment Options for Unruptured Intracranial Aneurysms
Published 2012-01-01“…Our paper summarizes the current body of literature in regards to the natural history of UIAs, the evolution of the lesion if it progresses uninterrupted, as well as the safety and efficacy of both treatment options. …”
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4543
Endometrial Carcinoma Presenting as Vasculitic Sensorimotor Polyneuropathy
Published 2011-01-01“…The phenomenon of a paraneoplastic syndrome can point to an underlying malignancy and can be used as marker of progression or regression of the tumor. Due to the rarity of PNP, there is no standard treatment. …”
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4544
Cinnamaldehyde for the Prevention and Control of Foodborne Pathogens and Their Biofilms: a Review of Research and Applications
Published 2025-01-01“…This paper summarizes recent progress in research on cinnamaldehyde’s antibacterial and anti-biofilm effects on common foodborne pathogens. …”
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4545
Peritoneal Adipocytes and Their Role in Inflammation during Peritoneal Dialysis
Published 2010-01-01“…An understanding of the inflammatory roles played by adipose tissue during PD and the healing mechanism of injured mesothelium will help to devise new therapeutic approach to slow the progression of peritoneal damage during peritoneal dialysis. …”
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4546
A survey on the visual perception of humanoid robot
Published 2025-03-01“…A key factor driving this transformation is the advancement of visual perception systems, which are crucial for making humanoid robots more intelligent and autonomous. Despite the progress, the full potential of vision-based technologies in humanoid robots has yet to be fully realized. …”
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4547
Ten Years of Earth and Space Science: Introduction to the Special Collection
Published 2025-01-01“…Such approach is consistent with the mission of most AGU journals, but the distinctive element for ESS is its focus on the concept of the useful impact of publication, progressively replacing that on conventional publication metrics. …”
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4548
Sensitivity and uncertainty analyses for a SARS model with time-varying inputs and outputs
Published 2006-04-01“…One feature of our analysis is the incorporation of time-dependentfunctions into the model to reflect the progressive refinement of these SARS controlmeasures over time. …”
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4549
Quality-by-design in pharmaceutical development: From current perspectives to practical applications
Published 2021-12-01“…The concept of quality-by-design (QbD) has been the focus of the current progress of pharmaceutical sciences. It is based on, but not limited, to risk assessment, design of experiments and other computational methods and process analytical technology. …”
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4550
Natural bioactive compounds form herbal medicine in Alzheimer’s disease: from the perspective of GSK-3β
Published 2025-02-01“…Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. …”
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4551
Terahertz Waveguides: A Bibliometric Analysis of the Past 20 Years
Published 2025-01-01“…This paper is a bibliometric analysis of the past twenty years’ research progress toward the terahertz waveguides and their propagation. …”
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4552
Cytokine and Growth Factor Activation In Vivo and In Vitro after Spinal Cord Injury
Published 2016-01-01“…The balance between the proinflammatory and anti-inflammatory effects of these molecules plays a critical role in the progression and outcome of the lesion. The excessive inflammatory Th1 and Th17 phenotypes observed after SCI tilt the scale towards a proinflammatory environment, which exacerbates the deleterious mechanisms present after the injury. …”
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4553
Compliant immune response of silk-based biomaterials broadens application in wound treatment
Published 2025-02-01“…More importantly, we describe the latest research progress in enhancing the immunotherapeutic and anti-inflammatory effects of composite materials prepared from silk from a mechanistic perspective. …”
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4554
False Gastric Diverticulum Arising from the Pylorus Associated with Gastric Outlet Obstruction
Published 2019-01-01“…A 59-year-old female presented with progressively worsening symptoms of gastric outlet obstruction associated with dyspepsia and vague abdominal pain for 5 years. …”
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4555
Chronic Kidney Disease in Disadvantaged Populations
Published 2012-01-01“…In addition, disadvantaged populations exhibit a broader spectrum of CKD risk factors and may be genetically predisposed to an earlier onset and a more rapid progression of chronic kidney disease. A basic understanding of the vulnerabilities of the disadvantaged populations will facilitate the adaptation and adoption of the kidney disease treatment and prevention guidelines for these vulnerable populations. …”
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4556
The Dendritic Cell-Regulatory T Lymphocyte Crosstalk Contributes to Tumor-Induced Tolerance
Published 2011-01-01“…In turn, Treg that expand during tumor progression contribute to the immune tolerance of cancer by impeding DCs' ability to orchestrate immune responses and by directly inhibiting antitumoral T lymphocytes. …”
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4557
The Interplay of Renin-Angiotensin System and Toll-Like Receptor 4 in the Inflammation of Diabetic Nephropathy
Published 2020-01-01“…Understanding the interplay of RAS and TLR4 in inducing the progression of DN may provide new insights to develop effective treatments.…”
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4558
Recent advances in functional assays of WRKY transcription factors in plant immunity against pathogens
Published 2025-01-01“…This article reviews the recent research progresses on WRKY TFs in regulating plant immunity, which includes both positive and negative regulation. …”
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4559
Semidefinite Optimization Providing Guaranteed Bounds on Linear Functionals of Solutions of Linear Integral Equations with Smooth Kernels
Published 2014-01-01“…Based on recent progress on moment problems, semidefinite optimization approach is proposed for estimating upper and lower bounds on linear functionals defined on solutions of linear integral equations with smooth kernels. …”
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4560
Microbiome and Colorectal Cancer in Humans: A Review of Recent Studies
Published 2025-01-01“…It has been challenging to elucidate the mechanisms by which gut microbiota contributes to carcinogenesis and cancer progression due to complex interactions with the host, including its metabolites and immune and inflammatory responses. …”
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