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4201
Chemokines and Cytokines as Salivary Biomarkers for the Early Diagnosis of Oral Cancer
Published 2013-01-01“…Thus it has been hypothesized that patients with oral cancer and oral potentially malignant lesions will have elevated levels of specific chemokines in oral fluids and that this may be used as a marker of both the early detection of malignant disease and progression to malignancy. The concept that salivary biomarkers can be easily measured and indicate disease states has profound consequences for clinical practice and may open up new strategies for the diagnosis, prognosis, and potential therapy of oral squamous cell carcinoma (OSCC). …”
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4202
A Review on JC Virus Infection in Kidney Transplant Recipients
Published 2013-01-01“…In case of immunodeficient hosts, JCV can lytically infect the oligodendrocytes, causing a fatal demyelinating disease, known as progressive multifocal leukoencephalopathy (PML). Although the reactivation of another human PyV, BK virus (BKV), is relatively common and its association with the polyomavirus associated nephropathy (PyVAN) following renal transplantation is proven, JCV replication and its impact on graft function and survival are less well studied. …”
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4203
Rationale for Antioxidant Supplementation in Sarcopenia
Published 2012-01-01“…Sarcopenia is an age-related clinical condition characterized by the progressive loss of motor units and wasting of muscle fibers resulting in decreased muscle function. …”
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4204
Huge Primary Parasitic Leiomyoma in a Postmenopausal Lady: A Rare Presentation
Published 2019-01-01“…The case presented is a 58-year-old grand-multiparous, menopausal lady with progressive abdominal swelling of three-year duration. …”
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4205
Use of Diagnostic Laparoscopy for Identification of Bilateral Noncommunicating Hydroceles in an Infant with Right-Sided Abdominoscrotal Mass and Left-Sided Scrotal Mass
Published 2017-01-01“…We present the case of a 4-month-old infant who presented with progressively enlarging bilateral scrotal swelling and a tense, ballotable right-sided abdominal mass with extension into the scrotum. …”
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4206
Severe Malaria in an Adult Patient from Low-Endemic Area in Flores Island, East Nusa Tenggara
Published 2023-01-01“…Plasmodium falciparum causes the most severe form of the disease and may progress to life-threatening manifestations. This case describes a 26-year-old man who suffered cerebral malaria with multiple organ dysfunction and successfully recovered despite poor initial prognosis. …”
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4207
The Use of Bacteria in Cancer Treatment: A Review from the Perspective of Cellular Microbiology
Published 2022-01-01“…Cellular microbiology, which is the interaction between harmful microbes and infected cells, is important in the determination of the bacterial infection processes and in the progression of data of different cellular mechanisms. …”
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4208
Biotechnological tools boost the functional diversity of DNA-based data storage systems
Published 2025-01-01“…We summarize the recent progress of how biotechnological tools, based on sequence specificity, encapsulation, and high-dimensional structures of DNA molecules, facilitate the implementation of various functions. …”
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4209
Ubiquitination Enzymes in Cancer, Cancer Immune Evasion, and Potential Therapeutic Opportunities
Published 2025-01-01“…We also discussed the recent update on small-molecule inhibitors and PROTACs and their progress in preclinical and clinical trials.…”
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4210
Infection-Induced Vulnerability of Perinatal Brain Injury
Published 2012-01-01“…A growing body of evidence demonstrates that susceptibility and progression of both acute and chronic central nervous system disease in the newborn is closely associated with an innate immune response that can manifest from either direct infection and/or infection-triggered damage. …”
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4211
A Neonate with CLOVES Syndrome
Published 2014-01-01“…Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi (CLOVE) syndrome is a recently delineated disorder that comprises vascular malformations (typically truncal), dysregulated adipose tissue, scoliosis, enlarged bony structures (typically of the legs) without progression, or distorting bony overgrowth. The name CLOVE was subsequently extended to CLOVES to emphasize the association with scoliosis/skeletal and spinal anomalies and seizures/central nervous system malformations. …”
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4212
Adaptive Immune Responses in Primary Cutaneous Sarcoidosis
Published 2011-01-01“…The development and progression of specific cutaneous sarcoidosis involves a complex interaction between cells of the adaptive immune systems, notably T-lymphocytes and dendritic cells. …”
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4213
Heterotopic Triplet Pregnancy after In Vitro Fertilization with Favorable Outcome of the Intrauterine Twin Pregnancy Subsequent to Surgical Treatment of the Tubal Pregnancy
Published 2014-01-01“…The intrauterine pregnancy progressed to the delivery by cesarean section of two healthy twins at 36+2 gestational age. …”
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4214
Development of Hematopoietic and Endothelial Cells from Human Embryonic Stem Cells: Lessons from the Studies using Mouse as a Model
Published 2007-01-01“…The current progress using the human embryonic stem cell (hESC) model system has provided much insight into the early origins of the hematopoietic and endothelial lineages, particularly the elusive hemangioblast. …”
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4215
PML-IRIS during Fingolimod Diagnosed after Natalizumab Discontinuation
Published 2014-01-01“…Natalizumab treatment is frequently discontinued and replaced by alternative medication in multiple sclerosis (MS) patients having a high risk of progressive multifocal leukoencephalopathy (PML). Case Presentation. …”
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4216
Urothelial Bladder Cancer with Cavitary Lung Metastases
Published 2011-01-01“…Transitional cell carcinoma (TCC) of the bladder tends to remain superficial; however, in 5% to 20% of cases, it progresses to muscle invasion and, more rarely, can metastasize. …”
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4217
From Infection to Tumor: Exploring the Therapeutic Potential of Ciprofloxacin Derivatives as Anticancer Agents
Published 2025-01-01“…This review explores progress in developing ciprofloxacin derivatives with anticancer properties, emphasizing key structural changes that improve their therapeutic effectiveness by modifying the basic group at position 7, the carboxylic acid group at position 3, or both. …”
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4218
Mandibular Brown Tumor of Secondary Hyperparathyroidism Requiring Extensive Resection: A Forgotten Entity in the Developed World?
Published 2015-01-01“…This is likely because early diagnosis and prompt treatment of this disease process prevent the progression and development of BTHPT. Conversely, BTHPT is more common in underdeveloped countries where fewer patients have access to health care and hyperparathyroidism (HPT) goes untreated. …”
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4219
Advances in small extracellular vesicles: roles in the tumor microenvironment and epithelial ovarian cancer diagnosis and treatment
Published 2025-02-01“…The tumor microenvironment (TME), a critical regulator of tumor progression, includes various components, among which small extracellular vesicles (sEVs) serve as important molecular carriers, having gained attention as significant contributors to cancer biology. …”
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4220
Stability of the RC Column under Horizontal Impacts
Published 2023-04-01“…Results of researches can be used for an estimation of resistance to the progressive collapse of reinforced concrete structures at their variants design and optimization.…”
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