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4161
Giant Ovarian Cyst: a Case Report
Published 2011-11-01“…He came to the General Teaching Hospital "Enrique Cabrera" referring volume increase progressive on the abdomen for a year and a half of evolution without another symptom companion in its beginning, but in recent months caused her lack of air before the efforts, urinated with more frequent than usual and with a lack of appetite. …”
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4162
Case report: Significant lesion reduction and neural structural changes following ibogaine treatments for multiple sclerosis
Published 2025-02-01“…Traditional therapies often fail to halt disease progression or reverse neurological deficits. Ibogaine, a psychoactive alkaloid, has been proposed as a potential neuroregenerative agent due to its multifaceted pharmacological profile. …”
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4163
Guillain-Barré Syndrome after H1N1 Shot in Pregnancy: Maternal and Fetal Care in the Third Trimester—Case Report
Published 2012-01-01“…Guillain-Barré syndrome is a rare neurological disease of progressive installation, usually following a previous acute infectious state, has a rare incidence, especially in pregnancy, and can induce major complications and high mortality risk. …”
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4164
Combination of Anti-programmed Cell Death Protein 1 and Antiangiogenesis Displaying a Response Disparity between Pulmonary and Nonpulmonary Metastases
Published 2023-10-01“…Both cases demonstrated a significant response in lung metastases; however, the nonpulmonary metastases progressed. These findings suggest that lung metastasis might have a distinct tumor immune microenvironment, and further studies to investigate the efficacy of PD-1/PD-L1-based combination therapy in patients with lung-limited metastases are warranted.…”
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4165
The Dynamic Spread of the Forward CDS with General Random Loss
Published 2014-01-01“…Let G={Gt;t≥0} be the progressive enlargement of F by (τ~,L); that is, G is the smallest filtration including F such that τ~ is a G-stopping time and L is Gτ~-measurable. …”
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4166
Reflexões sobre as incidências tributárias no Brasil e suas relações com o desenvolvimento socioeconômico nacional
Published 2018-01-01“…The placements resulting from the effort of this trial demonstrate that the STN cannot appropriate any of the ideals of the optimal taxation, neutrality, simplicity, progressivity, and fairness model. Finally, some suggestions of the literature for a tax reform in Brazil were discussed and the choice of a system with a high tax burden was highlighted, in the face of the search for a welfare state.…”
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4167
Long-Baseline Neutrino Oscillation Experiments
Published 2013-01-01“…A review of accelerator long-baseline neutrino oscillation experiments is provided, including all experiments performed to date and the projected sensitivity of those currently in progress. Accelerator experiments have played a crucial role in the confirmation of the neutrino oscillation phenomenon and in precision measurements of the parameters. …”
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4168
Enhancing the effectiveness of immunotherapy in rheumatoid arthritis by delaying immunosenescence triggered by fibroblast-like synoviocytes
Published 2025-01-01“…Abstract Rheumatoid arthritis (RA) is a prevalent autoimmune disorder primarily targeting the diarthrodial joints. During the progression of RA, fibroblast-like synoviocytes (FLSs) exhibit tumor-like behavior, including increased proliferation, inflammation mediation, and aggressive phenotypes, leading to bone erosion. …”
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4169
Unilateral Urogenital Disontogeny in a Dog
Published 2021-01-01“…An 8-year-old, mixed-breed, male dog, was referred because of progressive difficulties on defecation. A complete diagnostic work-up (hematological analysis, radiology, ultrasound, and computed tomography), followed by surgery and histopathology, allowed us to diagnose the condition as unilateral urogenital disontogeny. …”
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4170
Modeling evolution and persistence of neurological viral diseases in wild populations
Published 2008-09-01“…Viral infections are one of the leading source of mortality worldwide.The great majority of them circulate and persist in wild reservoirs and periodically spill over into humans or domestic animals.In the wild reservoirs, the progression of disease is frequently quite different from that in spillover hosts.We propose a mathematical treatment of the dynamics of viral infections in wild mammals using models with alternative outcomes.We develop and analyze compartmental epizootic models assuming permanent or temporary immunity of the individuals surviving infections and apply them to rabies in bats.We identify parameter relations that support the existing patterns in the viral ecology and estimate those parameters that are unattainable through direct measurement.We also investigate how the duration of the acquired immunity affects the disease and population dynamics.…”
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4171
Modern Endoscopic Imaging in Diagnosis and Surveillance of Inflammatory Bowel Disease Patients
Published 2018-01-01“…Advances in imaging have progressively added new tools into the armamentarium of endoscopists with the goal of more accurate, sensitive, and accessible visual diagnoses for the benefit of patients with gastrointestinal diseases. …”
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4172
Targeting Chondrocyte Hypertrophy as Strategies for the Treatment of Osteoarthritis
Published 2025-01-01“…During normal bone development, chondrocyte hypertrophy is a natural physiological process. However, in the progression of OA, chondrocyte hypertrophy becomes one of its key pathological features. …”
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4173
Heart Failure in Elderly Patients: Medical Management, Therapies and Biomarkers
Published 2024-12-01“…The incidence of HF progressively increases with age, reaching >10% in those aged 70 years or over. …”
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4174
Neuroinflammation in Parkinson's Disease and Related Disorders: A Lesson from Genetically Manipulated Mouse Models of α-Synucleinopathies
Published 2012-01-01“…Thus, the results in αS transgenic mice and related model mice are consistent with the idea that neuroinflammation in PD is a double-edged sword that is protective in the early stage of neurodegeneration but becomes detrimental with disease progression.…”
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4175
Hemorrhagic Colloid Cyst Presenting with Acute Hydrocephaly
Published 2017-01-01“…They mostly remain asymptomatic and sometimes grow progressively and cause diverse symptoms associated with increased intracranial pressure such as headache, diplopia, and sixth cranial nerve palsy. …”
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4176
Recent advances in iontophoresis-assisted microneedle devices for transdermal biosensing and drug delivery
Published 2025-04-01“…Integrating advanced manufacturing techniques and nanotechnology with cutting-edge materials has driven significant progress in global healthcare. Microneedles, recognized for their minimally invasive approach to transdermal sensing and drug delivery, achieve enhanced functionality when combined with iontophoresis. …”
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4177
Designing a Multi-Objective Closed-loop Supply Chain Mathematical Model with Supplier Selection Approach and considering Discount
Published 2023-03-01“…Moreover, the return of defective products to the production cycle and the general and progressive simultaneous discount policy have been considered through an integer linear mathematical model. …”
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4178
Current Status of the Open Abdomen Treatment for Intra-Abdominal Infection
Published 2013-01-01“…This review focuses on the specific use of the open abdomen in such populations and detailedly introduces current concerns and advanced progress about this therapy.…”
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4179
Systemic Levamisole-Induced Vasculitis in a Cocaine User without Cutaneous Findings: A Consideration in Diagnosis
Published 2015-01-01“…We report a case of a crack-cocaine user without cutaneous abnormalities who developed ANCA-associated glomerulonephritis that progressed to renal failure. This case demonstrates the difficulties in solidifying the diagnosis of levamisole-induced vasculitis in the absence of cutaneous findings and the need to pursue more testing to establish causality in ANCA-associated vasculitis that has potential for severe end-organ damage in patients who continue to use cocaine.…”
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4180
Cytokines as Therapeutic Targets for the Gastrointestinal Manifestations of Scleroderma
Published 2004-01-01“…Systemic sclerosis (SSc), or scleroderma, is a connective tissue disorder characterized by progressive fibrosis of the skin and internal organs. …”
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