Mechanisms of Neuroprotection by Protein Disulphide Isomerase in Amyotrophic Lateral Sclerosis by Adam K. Walker, Julie D. Atkin

“…Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterised by the progressive loss of motor neurons, leading to paralysis and death within several years of onset. …”
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A Binary Cuckoo Search Big Data Algorithm Applied to Large-Scale Crew Scheduling Problems by José García, Francisco Altimiras, Alvaro Peña, Gino Astorga, Oscar Peredo

“…The progress of metaheuristic techniques, big data, and the Internet of things generates opportunities to performance improvements in complex industrial systems. …”
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Anterior Uveitis as an Initial Manifestation of Polymyalgia Rheumatica by Hiromasa Tsuda, Kozue Tanaka, Shuji Kishida

“…Although the iridocyclitis disappeared within two weeks under topical steroid, she complained of acute progressing bilateral shoulder pain and morning stiffness of upper extremities. …”
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Improving Performance and Safety of Lithium Metal Batteries Through Surface Pretreatment Strategies by Gyuri Youk, Jeongmin Kim, Oh B. Chae

“…In addition, we reviewed the recent progress in pretreatment strategies using materials such as polymers, carbon materials, and inorganic compounds to suppress dendritic growth.…”
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Characteristics and Risk Factors for Spontaneous Closure of Idiopathic Full-Thickness Macular Hole by Xida Liang, Wu Liu

“…However, the full-thickness macular hole may close spontaneously, with a good visual acuity progress. Since recent studies are small-sample studies and case reports, the characteristics for spontaneous closure of idiopathic full-thickness macular holes are not fully understood. …”
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Discussion of irritable bowel syndrome issue and functional constipations in reports of the 21st United European Gastroenterological Week (Berlin, 2013) by A. A. Sheptulin, M. A. Vizye-Khripunova

“…Differential diagnostics of IBS with other diseases (celiac sprue, chronic inflammatory bowel diseases, et al.), that may progress under a mask of the functional intestinal disorders is required. …”
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Triggers for Atrial Fibrillation: The Role of Anxiety by Paolo Severino, Marco Valerio Mariani, Annalisa Maraone, Agostino Piro, Andrea Ceccacci, Lorenzo Tarsitani, Viviana Maestrini, Massimo Mancone, Carlo Lavalle, Massimo Pasquini, Francesco Fedele

“…Systemic arterial hypertension, diabetes, obesity, heart failure, and valvular heart diseases are major risk factors for the onset and progression of AF. Various studies have emphasized the augmented anxiety rate among AF patients due to the poor quality of life; however, little information is known about the possibility of triggering atrial fibrillation by anxiety. …”
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The Fate of Allogeneic Pancreatic Islets following Intraportal Transplantation: Challenges and Solutions by Xinyu Li, Qiang Meng, Lei Zhang

“…However, there are many obstacles contributing to the early mass loss of the islets and progressive islet loss in the late stages of clinical islet transplantation, including hypoxia injury, instant blood-mediated inflammatory reactions, inflammatory cytokines, immune rejection, metabolic exhaustion, and immunosuppression-related toxicity that is detrimental to the islet allograft. …”
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Epidermal Stem Cells in Wound Healing and Regeneration by Ronghua Yang, Jingru Wang, Xiaodong Chen, Yan Shi, Julin Xie

“…Skin stem cells distributed in the basal layer of the epidermis and hair follicles are important cell sources for skin development, metabolism, and injury repair. At present, great progress has been made in the study of epidermal stem cells at the cellular and molecular levels. …”
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Martha’s Dialogue with Jesus (John 11,21-27) in Light of the Psalms of Lament by Richard Francis D’Souza OCD

“…While the dialogue explains in advance the significance of the sign of raising Lazarus from the dead, it also highlights the progressive faith journey of Martha from the initial lament to the highest confession of faith in Jesus as the Messiah and the Son of God. …”
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Recent Advances in Chirally-Coupled Core Fibers by Mingheng Yuan, Mingheng Yuan, Yuan Sui, Yuan Sui, Zhenao Bai, Zhongwei Fan, Zhongwei Fan

“…Based on a brief description of the theory about CCC fiber, this article focuses on the research progress and application prospect of CCC fiber.…”
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Cardiovascular Disease in Ageing: An Overview on Thoracic Aortic Aneurysm as an Emerging Inflammatory Disease by Calogera Pisano, Carmela Rita Balistreri, Alessandro Ricasoli, Giovanni Ruvolo

“…Recent evidences propose the strong role of a chronic immune/inflammatory process in aneurysm evocation and progression. The coexistence of inflammatory cells with markers of apoptotic vascular cell death in the media of ascending aorta with aneurysms and type A dissections raises the possibility that activated T cells and macrophages may contribute to the elimination of smooth muscle cells and degradation of the matrix. …”
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Shönlein-Henoch Purpura in the Course of Chronic Primary Inmmune Thrombocytopenia. Presentation of a Case by Lucía Díaz Morejón, Belkis Lázara Rodríguez Jorge, Dumeivy García Sánchez

“…Lab tests, with the exception of platelet count, were within the normal limits. The progress was satisfactory in a three week period.…”
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Sjogren’s Syndrome and TAM Receptors: A Possible Contribution to Disease Onset by Richard Witas, Ammon B. Peck, Julian L. Ambrus, Cuong Q. Nguyen

“…Sjogren’s syndrome (SS) is a chronic, progressive autoimmune disease featuring both organ-specific and systemic manifestations, the most frequent being dry mouth and dry eyes resulting from lymphocytic infiltration into the salivary and lacrimal glands. …”
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Pharmacokinetics of Hyperthermic Intrathoracic Chemotherapy following Pleurectomy and Decortication by Paul H. Sugarbaker, O. Anthony Stuart, Christopher Eger

“…In patients with pseudomyxoma peritonei or peritoneal mesothelioma, direct extension of disease through the hemidiaphragm may result in an isolated progression of tumor within the pleural space. We monitored the intrapleural and plasma levels of mitomycin C and doxorubicin by HPLC assay in order to determine the pharmacokinetic behavior of this intracavitary use of chemotherapy. …”
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Advanced Esophageal Neoplasm with Subcutaneous Metastasis by Rivadávio A. M. de Oliveira, Tassiara da Silva, Mariana Miyasaki Piovesana, Carlos Eduardo Stecca, George A. Lopes, Vitor Teixeira Liutti

“…Later in time, we documented a disease progression, with worsening of subcutaneous implants, lymph node, bone, and pulmonary metastases in addition to malignant hypercalcemia. …”
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Stapled peptides: targeting protein-protein interactions in drug development by Qian Zhang, Ziyang Wang, Xiaohan Mei, Quan Chen, Chunqiu Zhang

“…This review outlined the continuous progress of stapled peptides mainly concerning the design principle, structural stability, bioactivity, cell permeability, and potential applications in therapeutics, which is aimed at providing a broad reference for the design and exploration of stapled peptides with enhanced biological and pharmacokinetic properties as the next-generation therapeutic peptide drugs targeting various diseases.…”
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Enhancing Mass Lesion of the Sphenoid: Atypical Presentation of Ongoing Pneumatization by Deepak Vallabhaneni, Anthony Mohamed, Zain Badar, Rajiv Mangla

“…We present a case of a 6-year-old boy with progressive headaches and neurologic symptoms suggestive of intracranial pathology. …”
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Alternative Splicing: Emerging Roles in Anti-Aging Strategies by Lingyue Gao, Rong Jia

“…In this review, we will summarize the latest research progress on alternative splicing in aging and cellular senescence, discuss the roles and regulatory mechanisms of alternative splicing during aging, and then excavate existing and potential approaches to anti-aging by controlling alternative splicing. …”
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Fibrodysplasia Ossificans Progressiva and Pregnancy: A Case Series and Review of the Literature by Alexandra D. Forrest, Danielle M. Vuncannon, Jane E. Ellis, Zvi Grunwald, Frederick S. Kaplan

“…To evaluate maternal and fetal outcomes in pregnant patients with fibrodysplasia ossificans progressiva (FOP; OMIM#135100), an ultrarare genetic disorder characterized by progressive heterotopic ossification of soft tissues and cumulative disability. …”
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