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3901
Association of Influenza Virus Proteins with Membrane Rafts
Published 2011-01-01“…Virus assembly is orchestrated by the matrix protein M1, binding to all viral components and the membrane. Budding progresses by protein- and lipid-mediated membrane bending and particle scission probably mediated by M2. …”
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3902
The role of NF-κB in diabetic cardiomyopathy
Published 2024-12-01“…Several transcription factors intricately participate in the initiation and progression of associated processes. Among these, nuclear factor kappa B (NF-κB), a pleiotropic transcription factor, assumes a crucial role in regulating oxidative stress, inflammatory response, endothelial dysfunction, myocardial fibrosis and hypertrophy, and cardiomyocyte apoptosis in DCM. …”
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3903
Role of the Gastrointestinal Tract Microbiome in the Pathophysiology of Diabetes Mellitus
Published 2017-01-01“…In recent years, the disease progression is particularly linked with functional and taxonomic alterations in the gastrointestinal tract microbiome. …”
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3904
Evaluating the advancements in protein language models for encoding strategies in protein function prediction: a comprehensive review
Published 2025-01-01“…Protein function prediction is crucial in several key areas such as bioinformatics and drug design. With the rapid progress of deep learning technology, applying protein language models has become a research focus. …”
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3905
Topological indices and their correlation with structural properties of carbon nanotube Y-junctions
Published 2025-03-01“…The obtained results clearly show that all these topological indices increase progressively across the different configurations of the Y-junctions, which evidences a direct relationship among the structural complexity and stability with their electronic properties.…”
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3906
Examination of the Behavior of Gravity Quay Wall against Liquefaction under the Effect of Wall Width and Soil Improvement
Published 2014-01-01“…The FLAC 2D software was used for analyzing and modeling progressed models of soil and loading under difference conditions. …”
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3907
Mesenchymal stromal cell exosomes for drug delivery of prostate cancer treatments: a review
Published 2025-01-01“…This review provides a comprehensive introduction to the advantages of these systems, current research trends and progress, as well as an analysis of current challenges and future research directions. …”
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3908
Th17 Cells in Immunity and Autoimmunity
Published 2013-01-01“…In this review we have provided a comprehensive overview of Th17 pathogenicity and function, including novel evidence for a protective role of Th17 cells in conjunction with the microbiota gut flora in T1D onset and progression.…”
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3909
Super-enhancers in tumors: unraveling recent advances in their role in Oncogenesis and the emergence of targeted therapies
Published 2025-01-01“…In tumor samples, super enhancers have been identified as crucial players in the development and progression of tumor cells, opening up new avenues for cancer research and treatment. …”
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3910
REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB)
Published 2018-01-01“…Dementia with Lewy bodies (DLB) is the third most common cause of dementia, and the typical clinical presentation is rapidly progressive cognitive impairment. RBD is one of the core features of DLB and may occur either in advance or simultaneously with the onset of DLB. …”
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3911
Cannabinoids and the endocannabinoid system in liver diseases
Published 2024-12-01“…Stimulation of the CB1 receptor may also lead to progression of liver steatosis and carcinogenesis. In end-stage liver disease, the endocannabinoid system plays an important role in the pathogenesis of encephalopathy and vascular effects, such as portal hypertension, splanchnic vasodilatation and cirrhotic cardiomyopathy. …”
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3912
Gender Politics in Nigeria: A Socio-Political Analysis of Women’s Perspectives on Feminism, Feminist Politics, and Democracy
Published 2025-02-01“…Wedged between modernity and patriarchy, they reject Western notions of sexual liberalism and conceptualize democracy as necessary but incapable of ensuring economic progress – the end for which it exists. The arguments in the present article matter because they contribute to feminist/political scholarship in Nigeria. …”
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3913
Basal Cell Carcinoma Masked in Rhinophyma
Published 2013-01-01“…Rhinophyma, the advanced stage of rosacea, is a lesion characterized by progressive hypertrophy and hyperplasia of sebaceous glandular tissue, connective tissue, and blood vessels. …”
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3914
Bromodomain-Containing Protein 4: A Dynamic Regulator of Breast Cancer Metastasis through Modulation of the Extracellular Matrix
Published 2012-01-01“…Recently, we have shown that the bromodomain-containing protein 4 or bromodomain 4 (Brd4) functions as an inherited susceptibility gene for breast cancer progression and metastasis. In this paper, we will discuss that host genetic background on which a tumor arises can significantly alter the biology of the subsequent metastatic disease, and we will focus on the role of Brd4 in regulating metastasis susceptibility.…”
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3915
Establishment of an effective photobioreactor for growing microalgae: A review
Published 2024-12-01“…This review discusses and analyzes the features of photobioreactor systems, their drawbacks, and the progress achieved in the field of microalgae production.…”
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3916
Different Angiogenic Potential in Low and High Grade Sporadic Clear Cell Renal Cell Carcinoma Is Not Related to Alterations in the von Hippel–Lindau Gene
Published 2009-01-01“…Differences in angiogenic activity within the group of ccRCCs were reported and strong genotype-phenotype correlations were found in patients with VHL disease, raising a question about the importance of VHL inactivation status in angiogenic behaviour and tumour progression.…”
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3917
Role of Transient Receptor Potential Canonical Channel 6 (TRPC6) in Diabetic Kidney Disease by Regulating Podocyte Actin Cytoskeleton Rearrangement
Published 2020-01-01“…Many studies have recently shown that transient receptor potential canonical channel 6 (TRPC6) in podocyte plays a critical role in the development and progression of proteinuric kidney disease by regulating its actin cytoskeleton rearrangement. …”
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3918
Urinary Markers of Tubular Injury in HIV-Infected Patients
Published 2016-01-01“…Renal disease is a common complication of HIV-infected patients, associated with increased risk of cardiovascular events, progression to AIDS, AIDS-defining illness, and mortality. …”
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3919
Lymphoma Presenting as Acute-Onset Dysphagia
Published 2015-01-01“…Six months later, the patient developed rapidly progressive hearing loss and vestibular dysfunction. …”
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3920
Geometry, Space, Configuration: a Meeting with Anna Sgrosso
Published 2019-06-01“…In particular, Anna Sgrosso’s proposal to use traditional representation systems (Monge, axonometry, perspective) in an unconventional manner led to an innovative interpretation of architecture –realized or in progress–, in which it is possible to identify structure and geometric genesis of the spaces. …”
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