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3841
The illnesses of Herod the Great
Published 2005-06-01“…His last decade was characterised by vicious strife within his family and progressive ill health. We review the nature of his illnesses and suggest that he had meningoencephalitis in 59 BC, and that he died primarily of uraemia and hypertensive heart failure, but accept diabetes mellitus as a possible underlying etiological factor. …”
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3842
The long goodbye: the relationship between lleftist parties and the Italian General Confederation of Labour (CGIL) after the end of the Italian Communist Party (PCI) (1992-2017)
Published 2020-07-01“…In the case of Italy, the Democratic Party, set up in 2007, embodies the weak-minded party version, progressively dismantling the relationship with the trade union movement and, in particular, with the CGIL. …”
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3843
Immunosuppressive Role of Myeloid-Derived Suppressor Cells and Therapeutic Targeting in Lung Cancer
Published 2018-01-01“…In view of the emerging importance of MDSCs in lung cancer, the treatment of targeting MDSCs will be useful to the control of the development and progression of lung cancer. However, the occurrence, metastasis, and survival of cancer is the result of multiple factors and multiple mechanisms, so combined treatments using different strategies will become the major therapy method for lung cancer in the future.…”
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3844
Le couple interactif texte / phrase dans l'histoire de la langue française
Published 2010-12-01“…We describe here the different types of theme progression used in the textual productions in Middle French. …”
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3845
Telecommunication Networks in Germany — Expanding with a Public Company
Published 2020-08-01“…Hence, the expansion of fibre optic lines is progressing too slowly. Government subsidy programmes create additional problems. …”
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3846
Pain Mechanism in Rheumatoid Arthritis: From Cytokines to Central Sensitization
Published 2020-01-01“…Although in recent years, through the implementation of targeted treatment and the introduction of disease-modifying antirheumatic drugs (DMARDs), the treatment of RA patients has made a significant progress, a large proportion of patients still feel pain. …”
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3847
Deep Brain Stimulation for Pantothenate Kinase-Associated Neurodegeneration
Published 2015-01-01“…Pantothenate kinase-associated neurodegeneration (PKAN) is usually associated with dystonia, which is typically severe and progressive over time. Pallidal stimulation (GPi DBS) has been carried out in selected cases of PKAN with drug-resistant dystonia with variable results. …”
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3848
Severe Gastrointestinal Hemorrhage due to Monkeypox Virus-Associated Proctocolitis
Published 2023-01-01“…In our case, monkeypox-induced proctocolitis progressed to severe rectal bleeding requiring one unit of packed red blood cells transfusion despite one week of tecovirimat (TPOXX) therapy. …”
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3849
Dysmorphic Short Stature: Radiological Diagnosis of Trichorhinophalangeal Syndrome
Published 2018-01-01“…A 14-year-old boy presented with short stature and distinctive facial features, and following the first clinical and biological evaluation, no precise diagnosis was reached. Progressive bilateral development of noninflammatory and painless deformity of his second finger required a radiological exam that highlighted the key elements (cone-shaped epiphyses) for final diagnosis. …”
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3850
Recent advanced applications of metasurfaces in multi-dimensions
Published 2023-02-01“…Here, we review the recent advances of metasurfaces in multi-dimensions, including light wavelength, polarization, orbital angular momentum(OAM), and angular response. Progress in these fields has brought new applications in areas such as imaging, display, communication, and information encryption, etc. …”
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3851
On the scaling of digital twins by aggregation
Published 2025-01-01“…Several examples are presented to illustrate core use cases, highlighting a progression to represent both natural and engineered systems. …”
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3852
The European Union Strategy for the Adriatic- Ionian Region: An Alternative to the European Integration in the Western Balkans?
Published 2020-12-01“…Despite the European Union (EU)-sponsored economic and political reforms, the Western Balkans has made little to no progress in several fields, including post-conflict reconciliation, post-socialist economic transformation, and democracy. …”
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3853
Massively Parallel Sequencing of a Chinese Family with DFNA9 Identified a Novel Missense Mutation in the LCCL Domain of COCH
Published 2016-01-01“…DFNA9 is a late-onset, progressive, autosomal dominantly inherited sensorineural hearing loss with vestibular dysfunction, which is caused by mutations in the COCH (coagulation factor C homology) gene. …”
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3854
Recurrent Focal Segmental Glomerulosclerosis: A Discrete Clinical Entity
Published 2012-01-01“…Focal segmental glomerulosclerosis refers to a set of particular histopathologic lesions in which steroid-resistant podocyte injury leads to patchy adhesions between the glomerular tuft and Bowman's capsule, followed by progressive glomerulosclerosis and proteinuric renal failure. …”
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3855
Outcome Prediction in Infectious Disease
Published 2024-10-01“…This review aims to critically evaluate the development and application of outcome prediction modalities in sepsis and other infectious diseases, highlighting the progress made and identifying areas for further research.…”
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3856
Molecular pathogenesis of Cryptosporidium and advancements in therapeutic interventions
Published 2025-01-01“…Additionally, we also review the research progress of chemotherapeutic targets against cryptosporidia-specific enzymes and anti-Cryptosporidium drugs (including Chinese and Western medicinal drugs), aiming at the development of more effective treatments for cryptosporidiosis.…”
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3857
Contemporary Trends in Pulsed Field Ablation for Cardiac Arrhythmias
Published 2024-12-01“…The last decade has yielded significant scientific progress and quickened interest in PFA as an energy modality leading to the emergence of the clinical use of PFA technologies for the treatment of atrial fibrillation. …”
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3858
Unusual Presentation of a Rare Disease: A Case Report of Fungal Necrotizing Otitis Media and Mastoiditis
Published 2025-01-01“…A 54‐year‐old female was presented who suffered from diabetes mellitus and end‐stage renal disease presenting with severe otalgia, initially thought to be necrotizing otitis externa. She rapidly progressed to total necrosis of the tympanic membrane. …”
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3859
Cell-Specific Aptamers as Emerging Therapeutics
Published 2011-01-01“…This paper summarizes progress in cell-SELEX techniques and highlights recent developments, particularly in the field of medically relevant aptamers with a focus on therapeutic and drug-delivery applications.…”
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3860
Innovative Strategies in Oncology: Bacterial Membrane Vesicle-Based Drug Delivery Systems for Cancer Diagnosis and Therapy
Published 2025-01-01“…This article reviews the latest progress in OMV engineering for tumour treatment and discusses the challenges associated with the use of OMV-based antitumour therapy in clinical practice.…”
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