Unmet needs of biochemical biomarkers for human prion diseases by Peter Hermann, Inga Zerr

“…The major challenges to overcome are non-invasive sampling and the exploration of new biomarkers that may predict the onset or reflect disease progression. This will become extremely important in the near future, when new therapeutics are clinically evaluated and eventually become available for treatment. …”
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Statins for Renal Patients: A Fiddler on the Roof? by Anabela Malho Guedes, Pedro Leão Neves

“…The authors review the possible effects of statins on the progression of renal disease and cardiovascular events in chronic kidney disease patients.…”
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Service public local des déchets ménagers. A la recherche d'indicateurs de performance. by Gérard Bertolini

“…This evaluation requires the definition of criteria and the selection of indicators in order to measure the  progress and to allow comparisons with other municipal waste services too. …”
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The Problem of the Written Sign Evolution К проблеме эволюции письменного знака До проблеми еволюції писемного знака... by I. V. Khmel'

“…In the article there is given the analysis of written sign progress and the supposition about the future development are given.…”
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Auditory Hallucinations in a Deaf Patient: A Case Report by Natalia Pedersen, René Ernst Nielsen

“…This case report describes the progression of symptoms in a young deaf female. Her initial psychotic symptoms occur at the age of 16, but she did not come into contact with a psychiatric treatment facility before the age of 27, where she felt symptoms were distressing. …”
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A Pulmonary Zebra: Adult Primary Pulmonary Synovial Sarcoma by Sheffield Sandra, Nwachukwu Chidi, Ashby Tracy

“…We present a case of PPSS in a 41-year-old woman, who complained of progressive dyspnea and left-sided chest pain.…”
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PROBLEMS OF ADAPTATION OF RUSSIAN ACCOUNTING AND CONTROL AND ANALYTICAL PRACTICES TO THE CHALLENGES OF THE DIGITAL ECONOMY by A. Bodyako

“…The article deals with the cause and effect basis of the problem of digital technologies the spread - one of the characteristic features of the future due to the progress in the microelectronics, information technology and telecommunications. …”
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A Rare Case of Tolosa-Hunt-Like Syndrome in a Poorly Controlled Diabetes Mellitus by Glenmore Lasam, Sakshi Kapur

“…We report a case of a 50-year-old female with diabetes mellitus who presented with progressive second, third, fifth, sixth, and eighth cranial nerve palsy. …”
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Update and Outlook for 2005 of Florida's BMP Program for Vegetable Crops by Celeste A. Gilbert, Eric H. Simonne

“…This publication is meant to answer some of these concerns and provide an update on the status of the BMP manual for vegetable crops, with an emphasis on the rule making progress and acceptable strategies for nutrient management. …”
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SOCIOLOGICAL MONITORING 2016-2017 OF INTERETHNIC RELATIONS IN THE REPUBLIC OF BURYATIA by E. Petrova

“…The factors that can lead to destabilization of the situation: a decrease in the standard of living of the population, the ethnic conditioning of the chances for social progress, the destructive influence of the mass media and the Internet, the weakening of the system of international upbringing have identified. …”
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Romain Debref, Le processus d’innovation environnementale face à ses contradictions : le cas du secteur des revêtements de sol résilients by Romain Debref

“…This thesis questions the relevancy of the process of environmental innovation in the sector of the resilient flooring in Europe facing to the challenge of sustainability. Even if technical progress might be observed as starting point, we assume this process and its concepts are also taken over by industrial groups to withstand environmental controversies. …”
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Mouse colorectal cancer organoids: Lessons from syngeneic and orthotopic transplantation systems by Yu Muta, Yuki Nakanishi

“…This article discusses the development and applications of these organoid systems, emphasizing their capacity to faithfully recapitulate in vivo tumor progression, metastasis, and the immune landscape.…”
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Understanding the oscillations of an epidemic due to vaccine hesitancy by Anthony Morciglio, R. K. P. Zia, James M. Hyman, Yi Jiang

“…Vaccine hesitancy threatens to reverse the progress in tackling vaccine-preventable diseases. …”
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Investigation of Friedel-Crafts Alkylation in the Presence of Supported Sulfonic Acid on Silica Gel by A. R. Kiasat, M. Karimi-Cheshmeali, R. Soleymani, H. Rajabzadeh

“…The solid acid supported on silica gel and then as an effective catalyst in Friedel-Crafts alkylation of alcohols and aromatic compounds was used. The reaction progress was controlled using thin layer chromatography and the reaction products were analyzed using IR spectroscopy devise. …”
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Phase II study with sorafenib plus radiotherapy for advanced HCC with portal and/or hepatic vein tumor thrombosis by Yirui Zhai, Liming Wang, Hong Zhao, Fan Wu, Lingxia Xin, Feng Ye, Wei Sun, Yan Song, Lijuan Niu, Huiying Zeng, Jingbo Wang, Yuan Tang, Yongwen Song, Yueping Liu, Hui Fang, Ningning Lu, Hao Jing, Shunan Qi, Wenwen Zhang, Shulian Wang, Ye-Xiong Li, Jianxiong Wu, Bo Chen

“…Participants underwent 40–66 Gy radiotherapy for the hepatic primary tumor and vein tumor thrombosis, with concurrent oral sorafenib (400 mg twice daily) until disease progression or unacceptable adverse events. The primary endpoint was median overall survival (mOS) and the secondary endpoints included overall response rate (ORR) per Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1 and Modified Response Evaluation Criteria in Solid Tumors (mRECIST), median progression-free survival (mPFS), time to tumor progression (TTP), tumor thrombosis control, and grade ≥3 adverse events. …”
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The health promoting sports coach: theoretical background and practical guidance by Benjamin Tézier, Kévin Barros, Susanna Geidne, Farid Bardid, Spartaco Grieco, Stacey Johnson, Sami Kokko, Barry Lambe, Arthur Lefebvre, Aoife Lane, Linda Ooms, Jan Seghers, Vassilis Sevdalis, Stephen Whiting, Anne Vuillemin, Aurélie Van-Hoye

“…Four steps were carried out: (1) defining the health-promoting sports coach and key action principles, (2) co-constructing progression stages using the settings-based approach, (3) identifying key actions for promoting health in different moments of coaching (i.e., before, during, and after training and competition, and outside of coaching), and (4) developing long-term intervention components. …”
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Atezolizumab, bevacizumab, pemetrexed and platinum for EGFR‐mutant NSCLC patients after EGFR TKI failure: A phase II study with immune cell profile analysis by Shang‐Gin Wu, Chao‐Chi Ho, James Chih‐Hsin Yang, Shu‐Han Yu, Yen‐Feng Lin, Shu‐Chin Lin, Bin‐Chi Liao, Ching‐Yao Yang, Yen‐Ting Lin, Chong‐Jen Yu, Ya‐Ting Chuang, Wei‐Yu Liao, Kah Yi Yap, Weng Si Kou, Jin‐Yuan Shih

“…Higher peritumour NK cell and lower peripheral helper T cell were associated with favourable ORR and longer PFS, respectively. After disease progression, the proportion of S100A9+ MDSC increased, but Treg cells decreased.…”
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β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis by Yijia Zhang, Xinya Zhu, Liyuan Chen, Tianyu Gao, Guang Chen, Jin Zhu, Guoyu Wang, Daiying Zuo

“…Furthermore, the functional impact of TAM-derived OSM on PDAC progression was evaluated through in vitro co-culture systems and an in vivo Panc02 lung metastasis model. …”
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Synthetic CB1 Cannabinoids Promote Tunneling Nanotube Communication, Cellular Migration, and Epithelial–Mesenchymal Transition in Pancreatic PANC-1 and Colorectal SW-620 Cancer Cel... by David A. Bunsick, Leili Baghaie, Yunfan Li, Abdulrahman M. Yaish, Emilyn B. Aucoin, Elizabeth Skapinker, Rashelle Aldbai, Myron R. Szewczuk

“…By initiating their communications for invasion, cancer cells can reprogram their cellular activities to initiate their proliferation and migration and uniquely counteract metabolic stress during their progression. During this reprogramming process, cancer cells’ metabolism and other cellular activities are integrated and mutually regulated by tunneling nanotube communications to alter their specific metabolic functional drivers of tumor growth and progression. …”
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