Primary Gliosarcoma of the Cerebellum in a Young Pregnant Woman: Management Challenges and Immunohistochemical Features by Marco Meloni, Salvatore Serra, Giulia Bellisano, Nikolaos Syrmos, Sanjeeva Jeyaretna, Mario Ganau

“…Surgical excision was followed by early recurrence and eventually disease progression because the patient refused adjuvant treatment to save her fetus. …”
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Vitamin Bs as Potent Anticancer Agents through MMP-2/9 Regulation by Ha Vy Thi Vo, Namdoo Kim, Hyuck Jin Lee

“…Their ability to modulate metalloenzymes involved in crucial cellular pathways implicated in cancer progression presents a compelling avenue for therapeutic intervention. …”
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PROTEOMIC PROFILING OF BLOOD-BASED BIOMARKERS IN THE EARLY DETECTION OF ALZHEIMERS DISEASE by Syeda Uroosa Hashmi, Fahad Farooq Lasi

“…Now AD is considered a chronic disease which progresses slowly with the consequences of various complex pathologies. …”
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Evolution of West Pomerania Towards a Green Region by Izabela Bludnik, Paulina Dąbrosz-Drewnowska, Hanna Pondel

“…In addition, the increase in environmental awareness, technological progress and the requirements of competitiveness of the market economy have led to increasing investment in economic transformation based on green ventures. …”
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Epi-Off versus Epi-On Corneal Collagen Cross-Linking in Keratoconus Patients: A Comparative Study through 2-Year Follow-Up by F. Cifariello, M. Minicucci, F. Di Renzo, D. Di Taranto, G. Coclite, S. Zaccaria, S. De Turris, C. Costagliola

“…To evaluate two different techniques of cross-linking: standard epithelium-off (CXL epi-off) versus transepithelial (CXL epi-on) cross-linking in patient with progressive keratoconus. Methods. Forty eyes from 32 patients with progressive keratoconus were prospectively enrolled from June 2014 to June 2015 in this nonblinded, randomized comparative study. …”
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Vitamin D3/VDR alleviates double-stranded RNA virus -induced biliary epithelial cell damage by inhibiting autophagy by Na Liu, Pu Zhao, Ping Cao, JunPeng Hui, YongKang Pan, Jiwen Cheng

“…To investigate the role of VDRs in the pathogenesis and progression of BA using in vitro and in vivo models. …”
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M1 and M2 Macrophage Polarization Correlates with Activity and Chronicity Indices in Lupus Nephritis by Chutima Chavanisakun, Rassamon Keawvichit, Nontawat Benjakul

“…In addition, macrophage populations correlated with disease progression, but the significance of this association in disease progression remains uncertain.…”
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Comparative Results of “Epi-Off” Conventional versus “Epi-Off” Accelerated Cross-Linking Procedure at 5-year Follow-Up by Cristina Ariadna Nicula, Dorin Nicula, Anca Maria Rednik, Adriana Elena Bulboacă

“…The aim of our study was to compare the long-term efficacy and safety of “epi-off” conventional and “epi-off” accelerated corneal cross-linking (CXL) in patients with progressive keratoconus. Methods. “Epithelial-off” (“Epi-off”) CXL using the conventional technique (3 mW/cm2, 30 minutes) was performed in 93 eyes of 93 patients (S-CXL group) and “epi-off” accelerated method (9 mW/cm2, 10 minutes) in 76 eyes of 76 patients with progressive KCN (A-CXL group). …”
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Identification of Anoikis-Related Genes in Chronic Kidney Disease Based on Bioinformatics Analysis Combined with Experimental Validation by Liu H, Mei M, Zhong H, Lin S, Luo J, Huang S, Zhou J

“…The principal pathways enriched were involved in cell cycle progression Toxoplasmosis, Cell adhesion molecules, Influenza A, Pathogenic Escherichia coli infection, Small cell lung cancer, Amoebiasis, TNF signaling pathway, and Leukocyte transendothelial migration. …”
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Real-world data of dacomitinib as first-line treatment for patients with EGFR-mutant non-small-cell lung cancer by Ji Eun Shin, Hyun Ae Jung, Sehhoon Park, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Myung-Ju Ahn, Byoung Yong Shim

“…Out of the 60 patients who experienced disease progression, 31 underwent tissue re-biopsy and 25 underwent liquid biopsy. …”
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The role of the Global Observatory in addressing Gender Based Violence in Sport+ by Hayley Truskewycz, Lombe Mwambwa

“…Primarily, the GO is tasked with mobilising actors to coordinate the development of shared measurement indicators and methods to track progress on gender equality and gender-based violence in PEPAS. …”
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CLEC11A-Driven Molecular Mechanisms in Intervertebral Disc Degeneration: A Comprehensive Multi-Omics Study by Jiang N, Wang Q, Hu Z, Tian X

“…Subsequent single-cell analysis suggested that CLEC11A, TREM1, and HMGN1 may play pivotal roles in IVDD progression by modulating chondrocyte function and inflammatory responses. …”
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Longitudinal MRI evaluation of the efficacy of non-enhanced lung cancer brain metastases by Xian Zhang, Jun Yang, Hong Hu, Yong Wang, Zhenfeng Zhang, Jinhao lv, Junping Li

“…In contrast, the median progression-free follow-up time for enhanced BM was 35.5 months, yielding a disease control rate of 100%. …”
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Inhibition of programmed cell death by melanoma cell subpopulations reveals mechanisms of melanoma metastasis and potential therapeutic targets by Yuepeng An, Fu Zhao, Hongling Jia, Siyu Meng, Ziwei Zhang, Shuxiao Li, Jiusi Zhao

“…Melanoma was distinguished by its rapid progression, high metastatic potential, and significant resistance to conventional therapies. …”
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Clinical outcomes of early remdesivir administration in hospitalized patients at high risk for severe COVID-19 during the Omicron wave by Yeon Ju La, Won Sup Oh, Changhyup Kim, Myoung-nam Lim, Yong Duk Jeon

“…Conclusions In our study, early remdesivir administration was not associated with preventing progression to severe disease when used as previously indicated during the Omicron wave. …”
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GPR137-RAB8A activation promotes ovarian cancer development via the Hedgehog pathway by Chao Tang, Lin Li, Chongying Zhu, Qiang Xu, Zihao An, Shouying Xu, Chao Lin

“…Abstract Background Ovarian cancer (OC) progression is one of the commonest cause of female cancer death. …”
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Mesenchymal stromal cells-derived extracellular vesicles in cartilage regeneration: potential and limitations by María Piñeiro-Ramil, Iván Gómez-Seoane, Ana Isabel Rodríguez-Cendal, Isaac Fuentes-Boquete, Silvia Díaz-Prado

“…Abstract Background Articular cartilage injuries can lead to pain, stiffness, and reduced mobility, and may eventually progress to osteoarthritis (OA). Despite substantial research efforts, effective therapies capable of regenerating cartilage are still lacking. …”
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Understanding the long‐term impact of the COVID‐19 pandemic on non‐muscle‐invasive bladder cancer outcomes: 12‐Month follow‐up data from the international, prospective COVIDSurg Ca... by Cameron E. Alexander, Arjun Nathan, Alexander Light, Chuanyu Gao, Vinson Chan, Sinan Khadhouri, Kevin Gallagher, Kevin G. Byrnes, Michael Walters, Terry Hughes, Rita Perry, Kelvin Okoth, Laura Magill, Thomas Pinkney, Joseph B. John, John S. McGrath, Alexandra Colquhoun, Yuhao Zhang, James Blackmur, Eric Etchill, Stanley Tang, Damián García Escudero, Grant D. Stewart, Veeru Kasivisvanathan, COVIDSurg Collaborative

“…Overall disease recurrence and progression rates were 29.3% and 9.7% at 12 months, respectively. …”
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Early risk assessment in paediatric and adult household contacts of confirmed tuberculosis cases by novel diagnostic tests (ERASE-TB): protocol for a prospective, non-interventiona... by Ursula Panzner, Katharina Kranzer, Tsitsi Bandason, Kuda Mutasa, Sandra Rukobo, Charles Sandy, Bariki Mtafya, Andrea Rachow, Norbert Heinrich, Michael Hoelscher, Judith Bruchfeld, Olena Ivanova, Nyanda Elias Ntinginya, Doreen Pamba, Laura Olbrich, Issa Sabi, Simeon Mwanyonga, Elmar Saathoff, Willyhelmina Olomi, Junior Mutsvangwa, Hazel M Dockrell, Edson Tawanda Marambire, Denise Banze, Alfred Mfinanga, Theodora D Mbunda, Khosa Celso, Gunilla Kallenius, Claire J Calderwood, Christof Geldmacher, Kathrin Held, Tejaswi Appalarowthu, Friedrich Rieß, Anna Shepherd, Christopher Sundling, Mishelle Mugava, Martha Chipinduro, Lwitiho Sudi, Antelmo Haule, Emmanuel Sichone, Paschal Qwaray, Harrieth Mwambola, Lilian Minja, Peter Edwin, Dogo Ngalison, Stella Luswema, Celina Nhamuave, António Machiana, Carla Madeira, Emelva Manhiça, Nádia Sitoe, Jorge Ribeiro

“…Better diagnostics, together with tools to predict disease progression, are critical for achieving WHO End-TB targets. …”
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Effects of celastrol on the heart and liver galaninergic system expression in a mouse model of Western-type diet-induced obesity and metabolic dysfunction-associated steatotic live... by Nikolina Canová, Jana Šípková, Mahak Arora, Zuzana Pavlíková, Zuzana Pavlíková, Tomáš Kučera, Ondřej Šeda, Tijana Šopin, Tomáš Vacík, Ondřej Slanař

“…Celastrol was administered along with a specific diet for the last 4 weeks to evaluate its impact on the progression of these conditions. Moreover, the inhibitor of sterol regulatory element-binding protein 1/2 (SREBP1/2), fatostatin, was also tested to compare its influence on the galaninergic system with celastrol.ResultsThe study demonstrates that celastrol treatment was safe and led to a reduction in food and energy intake, body fat and liver weights, and MASLD-to-MASH progression and improved glucose tolerance, serum biochemistry markers, and hepatic lipid peroxidation in mice. …”
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