Epigenetic Regulation of Stromal and Immune Cells and Therapeutic Targets in the Tumor Microenvironment by Kang Liu, Yue Li, Minmin Shen, Wei Xu, Shanshan Wu, Xinxin Yang, Bo Zhang, Nengming Lin

“…The tumor microenvironment (TME) plays a pivotal role in neoplastic initiation and progression. Epigenetic machinery, governing the expression of core oncogenes and tumor suppressor genes in transformed cells, significantly contributes to tumor development at both primary and distant sites. …”
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Remote Cerebellar Hemorrhage after Removal of a Supratentorial Glioma without Perioperative CSF Loss: A Case Report by Takuma Hara, Masahide Matsuda, Shinya Watanabe, Kei Nakai, Tetsuya Yamamoto, Akira Matsumura

“…He presented with severe headache, nausea, and vomiting for a few days, then he developed neurological deterioration including progressive disturbance of consciousness and left hemiparesis. …”
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Antibody-mediated degradation of 4R-tau restores mitochondrial membrane polarization in human induced pluripotent stem cell-derived neurons with the MAPT 10+16 mutation by Dale O. Starkie, Charles Arber, Terry Baker, Daniel J. Lightwood, Selina Wray

“…An imbalance causing excess 4 R tau is associated with diseases such as progressive supranuclear palsy and frontotemporal dementia. …”
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Pathogenic and therapeutic roles of extracellular vesicles in sepsis by Benshuai You, Yang Yang, Jing Wei, Chenglin Zhou, Surong Dong

“…In this review, we discuss the dual role of EVs in the progression and treatment of sepsis, exploring their intricate involvement in both inflammation and tissue repair processes. …”
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Update on the Management of Parkinson’s Disease for General Neurologists by Zvezdan Pirtošek, Ovidiu Bajenaru, Norbert Kovács, Ivan Milanov, Maja Relja, Matej Skorvanek

“…The last 10–15 years have seen great progress in the identification, evaluation, and management of PD, particularly in the advanced stages. …”
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Emotional perception of COVID-19 in Mexico: Comparative study between phase 1, phase 2 and the media by Isaias Vicente Lugo-González, Yuma Yoaly Pérez-Bautista, Ana Leticia Becerra-Gálvez, Margarita Fernández-Vega, Leonardo Reynoso-Erazo

“…Conclusions: The pandemic will have a progressive emotional impact as its phases progress and the importance of informing oneself in adequate means to prevent emotional consequences.…”
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Dihydroartemisinin inhibits EphA2/PI3K/Akt pathway-mediated malignant behaviors and vasculogenic mimicry in glioma stem cells by Huangde Fu, Shengtian Wu, Hechun Shen, Kai Luo, Zhongxiang Huang, Nankun Lu, Yaolin Li, Qian Lan, Yishun Xian

“…Gliomas, the most prevalent primary brain tumors, exhibit a poor five-year survival rate despite advances in various treatments, necessitating further studies to understand tumor progression and develop new therapies, particularly targeting EphA2, which is implicated in vasculogenic mimicry and glioma progression. …”
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The Dual Role of HLA-G in Cancer by Nathalie Rouas-Freiss, Philippe Moreau, Joel LeMaoult, Edgardo D. Carosella

“…For the past decade, HLA-G has been described as a tumor-escape mechanism favoring cancer progression, and blocking strategies have been proposed to counteract it. …”
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Expressions of CXCL12/CXCR4 in Oral Premalignant and Malignant Lesions by Juan Xia, Na Chen, Yun Hong, Xiaobing Chen, Xiaoan Tao, Bin Cheng, Yulei Huang

“…Our results indicated that CXCL12/CXCR4 axis may play roles from early steps of oral malignant transformation and contribute to the progress of oral carcinogenesis.…”
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Complete Radiologic Response of Metastatic Pancreatic Ductal Adenocarcinoma to Microwave Ablation Combined with Second-Line Palliative Chemotherapy by Hakon Blomstrand, Karin Adolfsson, Per Sandström, Bergthor Björnsson

“…The results were discouraging, with disease progression (liver and lung metastases) detected at the first evaluation; the progression-free survival was just two months (64 days). …”
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Exacerbation of Pulmonary Fibrosis Following Single Lung Transplantation by Dawei Yang, Jennifer M Wilson, Chunxue Bai, John Yee, Pearce G Wilcox, Nasreen Khalil, Robert D Levy

“…Acute exacerbations of interstitial lung disease present as clinical deteriorations, with progressive hypoxemia and parenchymal consolidation not related to infection, heart failure or thromboembolic disease. …”
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RNF128 deficiency in macrophages promotes colonic inflammation by suppressing the autophagic degradation of S100A8 by Xianwen Ran, Yue Li, Yahui Ren, Weilong Chang, Rui Deng, Huifen Wang, Weiwei Zhu, Yize Zhang, Yudie Cai, Jia Hu, Di Wang, Zhibo Liu

“…RNF128 deficiency leads to elevated levels of effector cytokines in vitro and accelerates the progression of IBD in mouse models. Bone marrow transplantation experiments revealed that RNF128 deficiency in bone marrow cells contributes to the worsening of DSS-induced colitis. …”
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Clinical Practice Guidelines of the Russian Scientific Liver Society, Russian Gastroenterological Association, Russian Association of Endocrinologists, Russian Association of Geron... by V. T. Ivashkin, M. V. Maevskaya, M. S. Zharkova, Yu. V. Kotovskaya, O. N. Tkacheva, E. A. Troshina, M. V. Shestakova, I. V. Maev, V. V. Breder, N. I. Gheivandova, V. L. Doshchitsin, E. N. Dudinskaya, E. V. Ershova, Kh. B. Kodzoeva, K. A. Komshilova, N. V. Korochanskaya, A. Yu. Mayorov, E. E. Mishina, M. Yu. Nadinskaya, I. G. Nikitin, N. V. Pogosova, A. I. Tarzimanova, M. Sh. Shamkhalova

“…Complications of nonalcoholic fatty liver disease include aggravation of cardiometabolic risks, development of hepatocellular cancer, progression of liver fibrosis to cirrhotic stage.Conclusion. …”
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The disparities and development trajectories of nations in achieving the sustainable development goals by Fengmei Ma, Heming Wang, Asaf Tzachor, César A. Hidalgo, Heinz Schandl, Yue Zhang, Jingling Zhang, Wei-Qiang Chen, Yanzhi Zhao, Yong-Guan Zhu, Bojie Fu

“…Abstract The Sustainable Development Goals (SDGs) provide a comprehensive framework for societal progress and planetary health. However, it remains unclear whether universal patterns exist in how nations pursue these goals and whether key development areas are being overlooked. …”
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Exploring Novel Non-Operative Treatments for Osteoarthritis: An Examination of Innovative Therapies by Piotr Robert Bakuła, Kamila Jałocha, Joanna Zygadło

“…Despite significant progress, challenges such as translational hurdles, cost barriers, and long-term efficacy require further investigation. …”
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Does Diabetes Mellitus Alter the Onset and Clinical Course of Vascular Dementia? by Santosh B. Murthy, Ali Jawaid, Salah U. Qureshi, Yogeshwar Kalkonde, Andrew M. Wilson, Michael L. Johnson, Mark E. Kunik, Paul E. Schulz

“…Multiple risk factors are associated with VaD, but the individual contribution of each to disease onset and progression is unclear. We examined the relationship between diabetes mellitus type 2 (DM) and the clinical variables of VaD.…”
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Editorial: BRICS in an Evolving World Order by M. Yu. Apanovich, Fulufhelo Netswera

“…The authors emphasize various facets of ongoing and evolving cooperation, delineating how BRICS nations engage with climate change, development assistance and collaboration, global governance reform, and the progressive advancement of the New Development Bank (NDB).…”
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Les régulations interactives et l’engagement des élèves : des soutiens à l’apprentissage by Catherine Tobola Couchepin

“…The multifocal analysis shows significant progress for all students. It highlights the language and the meanings shared in the teacher-student relationship.…”
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Implementing the Kids’ Athletics Program in the System of Increasing the Level of Physical Performance of Youth by Ján Jakubík, Jaroslav Broďáni

“…The difference in the progress of both samples was also determined.  Results. …”
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Nephrotic and Non-Nephrotic Focal Segmental Glomerulosclerosis: Clinical Characteristics, Etiology, and Columbia Classification by Gabriel Figueiredo, Luis Yu, Lectícia Barbosa Jorge, Viktoria Woronik, Cristiane Bitencourt Dias

“…Non-nephrotic patients with unfavorable progression were selected for ultrastructural analysis with electron microscopy. …”
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