Research progress of auricular acupoint stickingin the treatment of insomnia in the elderly (耳穴贴压治疗老年失眠患者的研究进展) by CHEN Li (陈丽), XIE Wei (谢薇), REN Xiuya (任秀亚), ZHAO Lingling (赵玲玲), XIANG Yiming (向毅明), ZHOU Yihan (周艺涵), LUO Liyuan (罗丽媛), LIU Xing (刘兴), SHAO Shuai (邵帅)

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Endogenous peptide CBDP1 inhibits clear cell renal cell carcinoma progression by targeting USP5/YTHDF2/TRPM5 axis by Yang Zhang, Wei Zhu, Ruijie Tao, Weijian Li, Chunming Jiang, Xiang Yan

“…Results: Our findings reveal that Cathepsin B Derived Peptide 1 (CBDP1) can inhibit the progression of ccRCC both in vitro and in vivo. Through mechanistic investigations, it was revealed that CBDP1 facilitates the interaction between YTHDF2 and the deubiquitinase USP5, thereby impeding the ubiquitination and degradation of YTHDF2. …”
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Progression of Luminal Breast Tumors Is Promoted by Ménage à Trois between the Inflammatory Cytokine TNFα and the Hormonal and Growth-Supporting Arms of the Tumor Microenvironment by Polina Weitzenfeld, Nurit Meron, Tal Leibovich-Rivkin, Tsipi Meshel, Adit Ben-Baruch

“…Breast cancer progression is strongly linked to inflammatory processes, aggravating disease course. …”
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Progressively complex neurorehabilitation: from a severe coma to a vegetative state, minimal consciousness ... and the Phoenix bird survives and is reborn from its ashes by Andreea-Iulia Vlădulescu-Trandafir, Aurelian Anghelescu, Ana-Andreea Cristea, Gelu Onose

“…The kinesiotherapy was progressively adapted to the neurologic and general condition. …”
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Research progress of virtual reality technology in the field of stroke rehabilitation (虚拟现实技术在脑卒中康复领域的研究进展) by BIAN Wenjie (边文杰)

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Significance of Glioma Stem-Like Cells in the Tumor Periphery That Express High Levels of CD44 in Tumor Invasion, Early Progression, and Poor Prognosis in Glioblastoma by Masahiro Nishikawa, Akihiro Inoue, Takanori Ohnishi, Shohei Kohno, Shiro Ohue, Shirabe Matsumoto, Satoshi Suehiro, Daisuke Yamashita, Saya Ozaki, Hideaki Watanabe, Hajime Yano, Hisaaki Takahashi, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda

“…These results imply the significance of GSCs with high levels of CD44 expression in the tumor periphery compared to the core, not only in tumor invasion but also rapid tumor progression and short survival in patients with GBM.…”
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Plasma matrix metalloproteinases and tissue inhibitors of metalloproteinases explored in relation to the severity and progression of diabetic retinopathy in patients with type 1 diabetes: baseline and prospective analyses by Sven Hector, Hans Olav Thulesius, Mona Landin-Olsson, Magnus Hillman, Eva Olga Melin, Maria Thunander

“…Only HbA1c was associated with the progression of DR in 267 patients with T1D.…”
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Research progress on influencing factors and interventions of post-stroke anxiety (脑卒中后焦虑影响因素及干预措施研究进展) by HOU Jing (侯静)

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CTSG is a prognostic marker involved in immune infiltration and inhibits tumor progression though the MAPK signaling pathway in non-small cell lung cancer by Qian Dai, Xufeng Yao, Yanke Zhang, Qian Chai, Xueyi Feng, Hongbin Zhu, Lei Zhao

“…Abstract Purpose This study aims to investigate the biological roles and molecular mechanisms of Cathepsin G (CTSG) in the progression of non-small cell lung cancer (NSCLC). Methods Western blotting and immunohistochemistry analyses of clinical samples were performed to determine the expression levels of CTSG in patients with NSCLC. …”
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Research Progress and Prospect of Extreme Water Increase by Storm Surge in Estuaries — A Case Study of Guangdong-Hong Kong-Macao Greater Bay Area by LIU Yuexuan, LI Huijing, LI Lanbin, LIU Xiaojian

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Identifying Key Biomarkers Related to Immune Response in the Progression of Diabetic Kidney Disease: Mendelian Randomization Combined With Comprehensive Transcriptomics and Single-Cell Sequencing Analysis by Hu M, Deng Y, Bai Y, Zhang J, Shen X, Shen L, Zhou L

“…Subsequently, the specific mechanisms of key regulatory genes involved in disease progression were analyzed through transcriptome and single-cell analysis. …”
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Chronic kidney disease progression in patients with previous type 2 diabetes and/or hypertension: a population-based cohort study from primary care in Spain by David Vizcaya, Betlem Salvador-González, Oriol Cunillera-Puértolas, Sílvia Cobo-Guerrero, José Romano-Sánchez, Daniel Bundó-Luque, Ariadna Arbiol-Roca

“…The strongest risk factors for CKD progression were low eGFR and albuminuria, even at mild-moderate levels.Conclusions Hypertension could be associated with an equal/greater risk of CKD progression as T2D. …”
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The Protection of the Right to Life at the Intersection between Reproductive Rights and Scientific Progress in the Jurisprudence of the Inter-American Court of Human Rights and the European Court of Human Rights by Simona Fanni

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Granulocyte-Macrophage Colony-Stimulating Factor-Activated Neutrophils Express B7-H4 That Correlates with Gastric Cancer Progression and Poor Patient Survival by Zhi-guo Shan, Zong-bao Yan, Liu-sheng Peng, Ping Cheng, Yong-sheng Teng, Fang-yuan Mao, Kun Fan, Yuan Zhuang, Yong-liang Zhao

“…In our study, neutrophils in tumor tissues were significantly higher than those in nontumor tissues and were positively associated with tumor progression but negatively correlated with GC patient survival. …”
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CD155 promotes the progression of colorectal cancer by restraining CD8+ T cells via the PI3K/AKT/NF-κB pathway by Rongpu Liang, Liting Liu, Dongbing Ding, Yiquan Li, Jiannan Ren, Bo Wei

“…Conclusion This study revealed that CD155 can promote the progression of colorectal cancer by regulating the PI3K / AKT-NF-κB pathway to promote the depletion of CD8+ T cells and reduce their migration to the tumor microenvironment. …”
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Research progress on the integrative nursing for patients with chronic bronchitis in China (中西医结合护理在慢性支气管炎患者中的研究进展) by SUN Ce (孙策)

“…This paper compares the differences between the TCM and Western medicine in the nursing of patients with chronic bronchitis, and exhibits the advantages of integrative nursing in controlling the progress of chronic bronchitis and focuses on the clinical application progress of integrative nursing in chronic bronchitis. …”
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Research progress of Traditional Chinese Medicine nursing for chest stuffiness and pain syndrome (胸痹心痛病中医护理的研究进展) by LI Jinghuan (李靖嬛), YUE Lina (岳丽娜)

“…This paper analyzed the current situation of TCM nursing application, summarizes the existing problems, analyzes the future research progress, and provided reference for the improvement of TCM nursing quality. …”
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Research progress of assessment tool and prevention of incontinence-associated dermatitis (失禁相关性皮炎评估工具和预防的研究进展) by MIAO Wenjing (苗文静), GUO Fengjuan (郭凤娟), CHEN Liuwen (陈柳文)

“…Based on the reviewing the relevant studies, this paper summarized the research progress of assessment tool and prevention of incontinence-associated dermatitis, in order to provide reference for clinical nurse to improve the accuracy in diagnosis and early intervention on IAD. …”
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miRNA-221: A Potential Biomarker of Progressive Liver Injury in Chronic Liver Disease (CLD) due to Hepatitis B Virus (HBV) and Nonalcoholic Fatty Liver Disease (NAFLD) by Parthana Rani Sutradhar, Nahida Sultana, Afzalun Nessa

“…Conclusion: miRNA-221 may be used as a potential plasma biomarker for early prediction of fibrosis progression in CLD patients.…”
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Analysis of Risk Factors for Postoperative Progressive Segment Degeneration at the Decompression and Non-decompression Segments after Minimally Invasive Lumbar Decompression Surgery: A 5-year Follow-up Study by Hasibullah Habibi, Hiromitsu Toyoda, Hidetomi Terai, Kentaro Yamada, Minori Kato, Akinobu Suzuki, Shinji Takahashi, Koji Tamai, Masayoshi Iwamae, Yuta Sawada, Yuto Kobayashi, Yuki Okamura, Hiroaki Nakamura

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