Progression patterns in patients with advanced hepatocellular carcinoma treated with local therapy, targeted drugs, and PD-1/PD-L1 inhibitors by Yanan Zhao, Di Wu, Quanjun Yao, Hang Yuan, Hongtao Hu, Hailiang Li

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Asymptomatic Intestinal Malrotation Progressing to Midgut Volvulus in a Decompensated Alcoholic Cirrhotic Adult: A Rare Scenario Requiring Special Considerations by Vatche Melkonian, Pablo Quadri, Chintalapati R. Varma, Mustafa Nazzal, Henry B. Randall, Minh-Tri J. P. Nguyen

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Research progress of peer education for stroke patients (同伴教育模式在脑卒中患者中的应用研究进展) by WU Yuanxia (吴远霞), WEI Yan (魏艳)

“…This review summarizes the domestic and foreign research progress on the application of peer education to stroke patients, in order to provide reference for clinical intervention of stroke patients. …”
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An overlap-weighted analysis on the association of constipation symptoms with disease progression and survival in amyotrophic lateral sclerosis: a nested case-control study by Tongyang Niu, Peize Wang, Xiaomeng Zhou, Tingting Liu, Qi Liu, Rui Li, Haitao Yang, Hui Dong, Yaling Liu

“…Patients with ALS constipation exhibited faster disease progression ( p  < 0.001), with a positive correlation between constipation severity and progression rate ( r  = 0.356, p  < 0.001). …”
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CREB3L1 facilitates pancreatic tumor progression and reprograms intratumoral tumor-associated macrophages to shape an immunotherapy-resistance microenvironment by Yu Wang, Haiyan Xu, Li Cai, Yang Sun, Liwei Wang, Ming Yue, Xiaofei Zhang, Yanling Wang, Shumin Li, Shengbai Xue, Jingyu Ma, Tiebo Mao, Weiyu Ge, Daiyuan Shentu, Wenxin Lu, Yongchao Wang, Jiong Hu, Jiujie Cui

“…Functionally, we confirmed CREB3L1 contributing to PDAC malignant progression including growth and metastasis by multiple in in vitro and in vivo models. …”
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Research progress on climate change adaptation strategies to control invasive crop pest in sub-Saharan Africa: a bibliometric and systematic review by Eméline Sêssi Pélagie Assèdé, Eméline Sêssi Pélagie Assèdé, Calvince Ouko Othoo, Calvince Ouko Othoo, Ahmadou Ly, Gobena Bayisa, Temesgen Gashaw Tarkegn, Temesgen Gashaw Tarkegn, Mègnissè Zohoun, Anje-Jokebed N’goran

“…This bibliometric and systematic review assesses research progress and climate change adaptation strategies to control invasive crop pests in sub-Saharan Africa. …”
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Numbness on the Medical Take: An Atypical Presentation of Guillain‐Barre Syndrome With Unilateral Paraesthesia and Rapid Progression to Bulbar Palsy: A Case Report by J. Stanley, Q. Zhou

“…ABSTRACT Guillain‐Barré syndrome (GBS) is characterized classically by progressive and symmetrical motor weakness and areflexia. …”
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The Prevalence and Progression of Microvascular Complications and the Interaction With Ethnicity and Socioeconomic Status in People With Type 2 Diabetes: A Systematic Review and Meta-Analysis by Thamer Alobaid, Janaka Karalliedde, Matthew DL O’Connell, Luigi Gnudi, Katie Sheehan, Ka Keat Lim, Salma Ayis

“…Conclusion: Ethnicity and SES may be associated with differential risk of development and progression of DN and DR. The available evidence was limited by the number of studies and small samples for certain ethnic/socioeconomic groups.…”
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Machine learning analysis of pathological images to predict 1-year progression-free survival of immunotherapy in patients with small-cell lung cancer by Hirotaka Matsumoto, Hiroaki Akamatsu, Nobuyuki Yamamoto, Yuki Sato, Daichi Fujimoto, Yoshihiko Taniguchi, Motohiro Tamiya, Yasuhiro Koh, Junya Fukuoka, Hisashi Tanaka, Naoki Furuya, Ryota Shibaki, Tsukasa Nozawa, Akira Sano, Yuka Kitamura, Takashi Kijima, Toshihide Yokoyama, Satoru Miura, Akito Hata, Jun Sugisaka

“…We trained a model to predict 1-year progression-free survival (PFS) using pathological images (H&amp;E, programmed cell death-ligand 1 (PD-L1), and double immunohistochemical assay (cluster of differentiation 8 (CD8) and forkhead box P3 (FoxP3)) and patient information. …”
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Research progress of standardization management of nosocomial infection control in the operating room (手术室医院感染规范管理研究进展) by XU Xu (徐旭), REN Guqun (任顾群), SU Yuqiang (苏玉强), WANG Yuena (王岳娜), XU Yuanle (许远乐)

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Upregulation of GSTP1 mediated by chimeric TFE3 promotes TFE3-tRCC progression by targeting JNK signaling pathway by Weixu Chen, Mengtong Wu, Lin Du, Changhua Fang, Hao Wang, Wendi Wang, Chengwei Zhang, Hongqian Guo, Gutian Zhang

“…Furthermore, GSTP1 was found to drive TFE3-tRCC progression via modulation of the JNK signaling pathway. …”
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Association between non-insulin-based insulin resistance indicators and frailty progression: a national cohort study and mendelian randomization analysis by Hui Tian, Yong-meng Li, Cheng-qiang Wang, Guo-qiang Chen, Ying Lian

“…Conclusions The non-insulin-based IR indicators, including TyG index, METS-IR and eGDR, were independently associated with the frailty progression and physical function decline. Monitoring and managing abnormal glucose metabolism should be recommended as a part of comprehensive strategies to prevent or delay the progression of frailty.…”
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LAMB1 downregulation suppresses glioma progression by inhibiting aerobic glycolysis through regulation of the NF-κB/HK2 axis by Zhenxiang Zhao, Haiying Liu, Yingzi Liu, Junpeng Wen, Jiangwei Yuan

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Activation of FGD5-AS1 Promotes Progression of Cervical Cancer through Regulating BST2 to Inhibit Macrophage M1 Polarization by Guokun Liu, Xuan Du, Li Xiao, Qing Zeng, QianLing Liu

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A handheld milk conductivity sensing device (Mylee) for measuring secretory activation progress in lactating women: a device validation study by Sharon Haramati, Anastasia Firsow, Daniela Abigail Navarro, Ravid Shechter

“…Here we evaluate the validity of a novel milk-sensing device (Mylee) for measuring the progress of milk maturation and secretory activation status. …”
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Bilateral Iliosacral and Transsacral Screws Are Biomechanically Favorable and Reduce the Risk for Fracture Progression in Fragility Fractures of the Pelvis—A Finite Element Analysis by Moritz F. Lodde, Matthias Klimek, Elmar Herbst, Christian Peez, Oliver Riesenbeck, Michael J. Raschke, Steffen Roßlenbroich

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Silencing hepatic PCSK9 via novel chimeric AAV8 mitigates the progression of atherosclerosis by inhibiting inflammation in ApoE−/− mice by Xiaocui Chen, Minghui Sun, Xiang Ma, Yitong Ma, Bangdang Chen

“…These findings indicate that targeted silencing of hepatic PCSK9 significantly reduces lipid levels and effectively mitigates atherosclerosis progression by inhibiting inflammatory responses via the AAV8.P-PCSK9 shRNA vector, thereby providing critical support for its clinical translation.…”
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Assessing Physician and Patient Agreement on Whether Patient Outcomes Captured in Clinical Progress Notes Reflect Treatment Success: Cross-Sectional Study by Sarah B Floyd, Jordyn C Sutton, Marvin Okon, Mary McCarthy, Liza Fisher, Benjamin Judkins, Zachary Cole Reynolds, Ann Blair Kennedy

“… BackgroundIt remains unclear if there is agreement between physicians and patients on the definition of treatment success following orthopedic treatment. Clinical progress notes are generated during each health care encounter and include information on current disease symptoms, rehabilitation progress, and treatment outcomes. …”
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Insights from serial cardiovascular magnetic resonance imaging show early progress in diastolic dysfunction relates to impaired right ventricular deformation by Sören J. Backhaus, Alexander Schulz, Torben Lange, Simon F. Rösel, Lennart S. Schmidt-Schweda, Shelby Kutty, Johannes T. Kowallick, Julia Treiber, Andreas Rolf, Samuel Sossalla, Gerd Hasenuß, Andreas Schuster

“…We hypothesized that serial real-time cardiovascular magnetic resonance (CMR) imaging at rest and during exercise-stress may detect early progress in pathophysiological alterations in HFpEF. …”
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Research progress in Traditional Chinese Medicine nursing of chronic atrophic gastritis (慢性萎缩性胃炎中医护理研究进展) by LIU Fenghua (刘凤华), ZHANG Xianyao (张先姚)

“…Chronic atrophic gastritis (CAG) is a common digestive system disease and a type of chronic gastritis disease progression. The study found that its incidence rate and detection rate increased significantly with age. …”
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