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17021
CDC20 and CCNB1 Overexpression as Prognostic Markers in Bladder Cancer
Published 2024-12-01“…Further studies with larger cohorts are needed to validate these findings and better understand the molecular mechanisms driving BC progression.…”
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17022
MiR-125b-5p ameliorates ox-LDL-induced vascular endothelial cell dysfunction by negatively regulating TNFSF4/TLR4/NF-κB signaling
Published 2025-01-01“…Abstract Background Oxidized low-density lipoprotein (ox-LDL)-induced endothelial cell dysfunction plays a crucial role in the progression of atherosclerosis (AS). Although miR-125b-5p is known to be involved in cardiovascular and cerebrovascular disorders, its function in ox-LDL-induced endothelial injury is still not well understood. …”
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17023
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17024
Establishment and characterization of a new mouse gastric carcinoma cell line, MCC
Published 2025-01-01“…Conclusions The MCC cell line serves as an indispensable model for gastric cancer research, offering a robust platform for investigating tumor development and progression. Its exceptional tumorigenic capacity and strong concordance with clinical proteomic profiles underscore its significance in translational research, facilitating the discovery of novel therapeutic targets and elucidation of molecular pathways critical for developing effective treatment strategies.…”
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17025
Long-Term Safety and Effectiveness of Dimethyl Fumarate in Patients with Multiple Sclerosis Treated in Routine Medical Practice: Final Analysis of the ESTEEM Study
Published 2024-12-01“…The estimated proportion of patients free from confirmed disability progression sustained over 48 weeks was 87.0% at month 60. …”
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17026
A leap forward: exploring the advantages of single-step genome evaluation in Italian Mediterranean buffalo
Published 2023-11-01“…Genomic information in the Italian Mediterranean Buffalo (IMB) is now available and its inclusion in the genetic evaluation system could increase both accuracy and genetic progress of the traits of interest of the breed. The aim of this study was to test the feasibility of ssGBLUP and to present the first results of the implementation of a genomic evaluation for production and type traits in the IMB. …”
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17027
Clinical and neurological specifics of the vertebrogenic lumbosacral radiculopathy course in the patients with RS1143627 polymorphism of the <i>IL-1β</i> gene
Published 2024-12-01“…Genetic polymorphism of the cytokine IL-1β contributes to the progression of VLSRP due to its increased production in certain genetic variants. …”
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17028
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17029
The serum level of sclerostin decreases in radiographic axial spondyloarthritis patients with fatty lesions
Published 2025-01-01“…Serum sclerostin might be useful as a biomarker to predict the progression of the chronic inflammation in SIJs in r-axSpA.…”
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17030
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17031
Current concepts of chronic gastritis and gastropathies: new international consensus RE.GA.IN
Published 2024-12-01“…Clinical strategies for the detection and eradication of H.pylori infection were developed, the previously unsuspected clinical and pathological significance of gastric microbiota was established, and extraordinary progress was made in the technology of esophagogastroduodenoscopy. …”
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17032
Item-level measurement properties of the pediatric awareness and sensory motor assessment in children with medical complexity
Published 2025-01-01“…Additional efforts will support health professionals to utilize the PASMA for baseline assessments, guiding personalized interventions, and tracking progress.ConclusionClinical use of the PASMA could provide new opportunities to detect subtle abilities, preferences, and changes in CMC, to promote meaningful participation and improve quality of life.…”
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17033
Soluble CD14 Enhances the Response of Periodontal Ligament Stem Cells to Toll-Like Receptor 2 Agonists
Published 2019-01-01“…Changes in the local sCD14 level may be considered as a crucial factor influencing the susceptibility of hPDLSCs to different pathogens and thus may contribute to the progression of periodontitis.…”
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17034
Parametric optimization of flow in a solar chimney power plant under variable semi elliptical constraints
Published 2025-01-01“…In higher flow parameter magnitude models, HSCPP-1 outperformed FSCPP-1 with a 4% enhancement in maximum velocity and up to 2% in temperature magnitude, emphasizing the positive influence of curvature heights (0.01–0.03 m) progressing towards minimal positive percentage enhancements.…”
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17035
Anti-Inflammatory and Anti-Migratory Effects of Morin on Non-Small-Cell Lung Cancer Metastasis via Inhibition of NLRP3/MAPK Signaling Pathway
Published 2025-01-01“…Collectively, these findings suggest that morin’s inactivation of the NLRP3 inflammasome pathway could offer a novel therapeutic strategy for counteracting pro-tumorigenic inflammation and metastatic progression in NSCLC.…”
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17036
Totally endoscopic mitral valve repair with novel technique of left atrial exposure: five years experience from a single center
Published 2025-01-01“…Abstract Background .Endoscopic mitral valve repair has progressively been adopted as the standard approach for treating isolated mitral regurgitation across numerous renowned cardiac surgery centers worldwide. …”
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17037
Prediction of pulmonary function decline in fibrous interstitial lung abnormalities based on quantitative chest CT parameters
Published 2025-01-01“…Fibrous ILA have a higher risk of progression and death. Clinically, computed tomography (CT) examination is a frequently used and convenient method compared with pulmonary function tests. …”
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17038
Integrated analysis of cell cycle and p53 signaling pathways related genes in breast, colorectal, lung, and pancreatic cancers: implications for prognosis and drug sensitivity for...
Published 2024-12-01“…Among various types, lung cancer is the most prevalent with high morbidity, while breast, colorectal, and pancreatic cancers also show high mortality rates. Cancer progression often involves disruption in cell cycle regulation and signaling pathways, with mutations in genes like TP53, EGFR, and K-RAS playing significant roles. …”
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17039
Investigation of <i>ITGB3</i> Heterogeneity to Overcome Trastuzumab Resistance in HER2-Positive Breast Cancer
Published 2024-12-01“…HER2-positive breast cancer has an aggressive tumour progression among breast cancers characterized by the overexpression of HER2. …”
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17040
Hiperoxaluria secundaria: causas y consecuencias de la enfermedad renal crónica
Published 2025-01-01“…At present, we do not have specific treatments for secondary hyperoxaluria, so early diagnosis and measures aimed at preventing the progression of kidney failure are currently the main therapeutic tools.…”
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