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Estimation of tuberculosis incidence at subnational level using three methods to monitor progress towards ending TB in India, 2015–2020
Published 2022-07-01“…Objectives We verified subnational (state/union territory (UT)/district) claims of achievements in reducing tuberculosis (TB) incidence in 2020 compared with 2015, in India.Design A community-based survey, analysis of programme data and anti-TB drug sales and utilisation data.Setting National TB Elimination Program and private TB treatment settings in 73 districts that had filed a claim to the Central TB Division of India for progress towards TB-free status.Participants Each district was divided into survey units (SU) and one village/ward was randomly selected from each SU. …”
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CD20 Negative Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type with Rapidly Progressing Skin Lesions
Published 2023-09-01“…The lesions were not painful or pruritic but progressed rapidly over the 3 months. Fever, night sweats, weight loss, and other systemic symptoms were absent. …”
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Factors protecting against progression of myopia in school students exposed to societal change in Vietnam: a 3-year cohort study
Published 2025-01-01“…In contrast, a study using computers was significantly associated with greater myopic progression in SE (β=−0.184; 95% CI: −0.699 to –0.112) and AL elongation (β=0.208; 95% CI: 0.062, 0.263).Conclusion This longitudinal assessment revealed both myopia incidence and progression and identified myopia-risk and myopia-protective behavioural factors in a Vietnamese cohort of secondary school students. …”
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Synergistic effect of defocus incorporated multiple segment glasses and repeated low level red light therapy against myopia progression
Published 2025-02-01“…Abstract Defocus incorporated multiple segment (DIMS) lenses and repeated low-level red-light (RLRL) are used to retard myopia progression. However, it is currently unknown if there is a synergistic effect of the two interventions. …”
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The RNA M5C methyltransferase NSUN2 promotes progression of hepatocellular carcinoma by enhancing PKM2-mediated glycolysis
Published 2025-02-01“…In addition, rescue assays revealed that NSUN2 promotes HCC glycolysis and progression by upregulating PKM2. In conclusion, this study revealed that NSUN2-mediated m5C modification promotes glycolysis and the progression of hepatocellular carcinoma by stabilizing PKM2 mRNA, and provides a potential prognostic factor and therapeutic target for HCC patients.…”
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p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways.
Published 2004-08-01“…Here, we used a multistage model of squamous cell carcinoma development to investigate the functional interactions between Ras, p19(Arf), and p53 during tumor progression in the mouse. Skin tumors were induced in wild-type, p19(Arf)-deficient, and p53-deficient mice using the DMBA/TPA two-step protocol. …”
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NOP2/Sun RNA Methyltransferase 4 Regulates the Mammalian Target of Rapamycin Signaling Pathway to Promote Hepatocellular Carcinoma Progression
Published 2025-01-01“…The influence that NSUN4 exerted on HCC malignant progression could be reduced by the inhibitor of the mTOR pathway. …”
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Low earth orbit satellite communication supporting direct connection with mobile phones: key technologies, recent progress and future directions
Published 2023-02-01“…In order to realize anytime and anywhere communication, low earth orbit (LEO) satellite communication becomes a key component in 6G.Through the adaptive enhancement of terrestrial mobile communication protocol, LEO satellites can provide direct connection services for mobile phones.The related key technologies and the recent progress of various commercial programs were introduced, and future issues were also identified together with potential technical solutions.…”
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Lymphocyte-C-reactive protein ratio upon admission to predict disease progression and ICU admission in adult patients with diabetic ketoacidosis
Published 2025-01-01Subjects: Get full text
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The Role of Pulmonary Metastasectomy in Breast Cancer with Limited Progression Following CDK4/6 Inhibitor Therapy: A Case Report
Published 2024-12-01Subjects: Get full text
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Integrative pan-cancer analysis and experiment validation identified GLS as a biomarker in tumor progression, prognosis, immune microenvironment, and immunotherapy
Published 2025-01-01“…In conclusion, GLS is an underlying biomarker for oncological progression, prognosis, TME, antitumor drug sensitivity, and immunotherapy response. …”
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Downregulation of hnRNPA1 inhibits hepatocellular carcinoma cell progression by modulating alternative splicing of ZNF207 exon 9
Published 2025-01-01“…We identified that hnRNPA1 bound to ZNF207 and regulated its exon 9 skipping, influencing ZNF207 splicing and the PI3K/Akt/mTOR pathway, key regulators of cell growth and survival.ConclusionOur findings demonstrate that hnRNPA1 promotes HCC progression by regulating ZNF207 splicing and the PI3K/Akt/mTOR pathway. hnRNPA1-ZNF207 interaction represents a potential therapeutic target for HCC, providing insights into the molecular mechanisms underlying HCC progression.…”
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Identification of Alzheimer’s Disease Progression Stages Using Topological Measures of Resting-State Functional Connectivity Networks: A Comparative Study
Published 2022-01-01“…However, in terms of clustering coefficient, 52 brain parcels sensitive to AD progression were identified in rs-FC networks built with GIG-ICA, much more than PC (6 parcels) and DTW (3 parcels). …”
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