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Plasma miRNAs in polycystic ovary syndrome drive endometrial cancer progression: insights into molecular pathways and therapeutic targets
Published 2025-02-01“…Our findings suggest that aberrant miRNA expression, particularly miR-330 and miR-424, may play crucial roles in UCEC progression. The identified miRNAs and candidate drugs may serve as potential therapeutic targets for UCEC, but further research is required to validate and explore their clinical applications.…”
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Injury mortality in South Africa: a 2009 and 2017 comparison to track progress to meeting sustainable development goal targets
Published 2024-12-01“…In the absence of reliable routine data, survey data allow to accurately assess the country’s SDG progress through commitment to evidence-based policymaking.…”
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CRAT downregulation promotes ovarian cancer progression by facilitating mitochondrial metabolism through decreasing the acetylation of PGC-1α
Published 2025-01-01“…In summary, CRAT functions as a critical tumor suppressor in OC progression by enhancing PGC-1α-mediated mitochondrial biogenesis and metabolism, suggesting CRAT as a potential therapeutic target in treatment of OC.…”
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Association between the Number of Childbirths and the Progress of Atherosclerosis among Women with Diabetes: A Cohort Study Based on Chinese Population
Published 2019-01-01“…The aim of this study is to explore the association between the number of childbirths and the progress of atherosclerosis among Chinese women with hypertension or diabetes. …”
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Progress towards 90-90-90 and 95-95-95 strategy implementations and HIV positivity trends in the City of Johannesburg
Published 2023-12-01“…This study has established positive progress made by the CoJ towards HIV testing, ART initiation, viral load suppression and HIV positivity rate. …”
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The impact of foreign direct investment on green technology progress in China on two-carbon background: taking trade openness into consideration
Published 2025-01-01Subjects: “…green technology progress…”
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Molecular Characterization of the Onset and Progression of Colitis in Inoculated Interleukin-10 Gene-Deficient Mice: A Role for PPARα
Published 2010-01-01“…The aims were to (1) characterize colitis onset and progression using a histopathological, transcriptomic, and proteomic approach and (2) investigate links between PPARα and IL10 using gene network analysis. …”
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Heat shock transcription factor 1 facilitates liver cancer progression by driving super‐enhancer‐mediated transcription of MYCN
Published 2024-09-01“…However, the specific roles of HSFs in hepatocellular carcinoma (HCC) have yet to be fully elucidated.Aims:To explore the involvement of the HSF family, particularly HSF1, in the progression and prognosis of HCC. Materials & Methods We conducted a thorough analysis of HSF expression and copy number variations across various cancer datasets. …”
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RETRACTED ARTICLE: hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer
Published 2013-11-01“…We identified a novel signaling pathway that sustains angiogenesis and progression in colorectal cancer (CRC). This pathway is triggered by β1 integrin-mediated adhesion and leads to VEGF-A secretion. …”
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Risk factors affecting progression and course of primary open-angle glaucoma in patients with different disease stages (multicenter study)
Published 2022-05-01“…Risk factors affecting progression and course of primary open-angle glaucoma in patients with different disease stages (multicenter study). …”
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Sintilimab for treating progressive multifocal leukoencephalopathy caused by human polyomavirus 2 virus infection following allogeneic hematopoietic cell transplantation: a case report
Published 2025-12-01Subjects: “…Progressive multifocal leukoencephalopathy…”
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Analysis of the effects of group progressive resistance training on inflammatory markers, cardiovascular fitness parameters, and respiratory function in elderly patients with chronic obstructive pulmonary disease
Published 2025-01-01“…Background: To investigate the effects of implementing group progressive resistance training on Maximal Oxygen consumption (VO2max), Maximum Ventilation per minute (VEmax), Maximal Oxygen pulse (O2pulsemax), Maximum Heart Rate (HRmax), and Modified Medical Research Council dyspnea scale (mMRC) in elderly patients with chronic obstructive pulmonary disease. …”
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Surgical management of single-level thoracolumbar vertebral body segmentation and formation failure causing progressive thoracolumbar myelopathy in three adult large-breed dogs
Published 2025-01-01“…The medium-term outcome was determined based on the neurological examination and follow-up imaging studies conducted up to 12 months post-operation.ResultsThree large-breed dogs were identified, presenting with progressive, non-painful T3–L3 spinal cord segment disease. …”
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Association between meniscal extrusion and disease severity in knee osteoarthritis: a retrospective case-control study
Published 2024-12-01Subjects: Get full text
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